Nucala is used with other medicines to control and prevent symptoms such as shortness of breath, wheezing, etc., caused by asthma. In addition, the prescription drug Nucala is also used in the treatment of certain diseases of the immune system such as eosinophilic syndrome, eosinophilic granulomatosis.

When the body is exposed to an allergen, eosinophils will appear in the esophagus, gastrointestinal tract, and small intestine. Eosinophilic esophagitis is an eosinophilic infiltration of the esophagus that causes clinical symptoms. This pathology is characterized by concentric circles appearing in the esophagus on endoscopic observation, the disease can cause symptoms of dysphagia, choking and complications of esophageal stricture and perforation.

Eosinophils are one of the components of white blood cells produced in the bone marrow and are one of the cells that play a role in promoting inflammation, especially allergic inflammatory reactions. Therefore, large quantities of eosin can accumulate in tissues such as the esophagus, stomach, small intestine and sometimes in the blood when such individuals are exposed to the allergen.

Eosinophils are one of the components of white blood cells produced in the bone marrow and are one of the cells that play a role in promoting inflammation, especially allergic inflammatory reactions. Accordingly, experimental treatment of PPI after diagnostic endoscopy is required before EoE is diagnosed, which is an ideal condition to be able to distinguish EoE from PPI - REE at baseline before this PPI testing.

Eosinophilic esophagitis (EoE) is an immune-mediated clinical condition presenting with symptoms of esophageal dysfunction and esophageal eosinophilia. Because of the presence of eosinophilia and response to PPI therapy, GERD and PPI-REE have become the most common alternative diagnoses for EoE.

Proton pump inhibitor-responsive eosinophilia should be suspected if esophageal symptoms and eosinophil histological findings demonstrate a symptomatic and histological response to proton pump inhibitors.

Eosinophils are one of the components of white blood cells produced in the bone marrow and are one of the cells that play a role in promoting inflammation, especially allergic inflammatory reactions. Accordingly, experimental treatment of PPI after diagnostic endoscopy is required before EoE is diagnosed, which is an ideal condition to be able to distinguish EoE from PPI - REE at baseline before this PPI testing.

Eosinophilic esophagitis (abbreviated as EoE) is an emerging chronic esophageal disease, first described in 1993, with increasing incidence and prevalence in Western countries. Accordingly, esophageal eosinophilia when exposed to high concentrations of esophageal acid when monitoring esophageal pH or in response to proton pump inhibitor therapy (PPI) is reflux esophagitis (GERD). ), while pH monitoring is normal or unresponsive to PPIs is eosinophilic esophagitis (EoE).

There are many causes of eosinophilia. Blood tests can measure eosinophil levels. Peripheral eosinophilia can be divided into three types: primary, secondary, and idiopathic.

Penicillin allergy is an overreaction of the immune system to the antibiotic penicillin and other related drugs. It is the most common type of drug allergy and can cause a range of symptoms from rashes to anaphylactic shock, which can be life-threatening.

Eosinophilic esophagitis is not very common so it is rarely noticed by patients. Moreover, the symptoms of the disease are similar to many other common diseases, so the disease is often detected late, causing serious effects on the patient's health. Below are some methods for early and effective diagnosis.