Welgra 100 contains Sildenafil 100mg, its main ingredient, along with other excipients. This medication is prescribed by doctors to treat erectile dysfunction in men.
1. Uses of Welgra 100
Welgra 100 contains Sildenafil 100mg as its main ingredient, along with various excipients. It is effective in treating erectile dysfunction, which is the inability to achieve or maintain an erection sufficient for satisfying sexual activity in men.
Sildenafil in Welgra 100 selectively inhibits the enzyme PDE5, leading to an increase in cGMP levels in the corpus cavernosum. This action relaxes smooth muscles and enhances blood flow to the corpus cavernosum, resulting in improved erections.
Welgra 100 is prescribed for patients who engage in sexual stimulation to achieve the best treatment results.
2. Contradiction of Welgra 100
Individuals contraindicated for Welgra 100 include:
- Women and children under 18 years.
- Those with hypotension (blood pressure < 90/50 mmHg), and those with liver failure.
- Those taking substances that contain nitric oxide or organic nitrates simultaneously.
- Those with hereditary degenerative retinal disorders, such as retinitis pigmentosa.
- Those who have experienced a myocardial infarction or a recent stroke.
- Those who are allergic to any ingredient of the medication.
3. How to use and dosage of Welgra 100
Welgra 100 should be taken orally one hour before sexual intercourse. Men should not take this medication more than once a day.
It is important to strictly follow the dosage prescribed by physicians. The dosage may be adjusted based on each individual’s specific condition. The following dosages are for reference only.
Adults
Take 50 mg a day, regularly. The dose of Welgra 100 may be increased to a maximum of 100 mg or reduced to 25 mg depending on individual tolerance.
Patients with renal failure
For patients with renal failure, the dosage of Welgra 100 should be adjusted according to the severity of the condition:
- Mild or moderate renal failure (creatinine clearance 30 - 80ml/minute): Take the dose as recommended for adults (50 mg per day) without adjustment.
- Severe renal failure (creatinine clearance < 30ml/minute): The recommended dose is 25 mg per day.
Patients with liver failure
Take the dose of 25mg a day
Patients who are taking other medications should be aware of the following guidelines:
- Ritonavir: The maximum single dose of Welgra 100 should not exceed 25 mg within 48 hours.
- CYP3A4 inhibitors: Start with an initial dose of 25 mg of Welgra 100.
- Alpha-adrenergic blocking drugs: Patients should be stabilized before taking Welgra 100. It is advisable to consider starting with a lower dose of Welgra 100.
There is no need to adjust the above dose for the elderly. Children under 18 years of age should not use Welgra 100.
4. Handling of missed doses or overdoses of Welgra 100
Welgra 100 is typically taken on an as-needed basis, so missed doses are uncommon. However, if you do miss a dose, simply skip it. Remember to take the medication 1 hour before your next sexual intercourse, and do not take 2 doses at the same time.
If someone takes too much Welgra 100, they may experience symptoms such as hot flashes, visual changes, dizziness, headache, nasal congestion, and indigestion. They need to inform their doctor and seek medical assistance immediately for appropriate care.
5. Side effects of Welgra 100
The common side effects of Welgra 100 include headaches. Some less common symptoms are blurred vision, hot flashes, indigestion, dizziness, nasal congestion, nausea, and astigmatism.
Additional less common symptoms may vary depending on individual constitution, including:
- Drowsiness, photophobia (sensitivity to light), eye congestion, tachycardia (rapid heartbeat), nosebleeds, vomiting, rashes, eye pain, rhinitis (nasal inflammation), and dizziness.
- Palpitations, sinus congestion, dry mouth, gastroesophageal reflux, musculoskeletal pain, visual disturbances, hypotension (low blood pressure).
- Edema (swelling), dry eyes, epilepsy, abnormal sensations in the eyes, hoarseness, voice changes, itching, nasal edema, and fainting.
- Rarely, recurrent epilepsy and unexpected erections may occur.
If the above symptoms do not improve or worsen, the patient should immediately notify the treating physician for timely advice and support.
6. Drug interactions Welgra 100
Patients should be open and honest with their doctors about all medications they are taking to avoid interactions with Welgra 100 and enhance their treatment effectiveness. Particularly, use Welgra 100 cautiously with the following types of medications:
- CYP3A4 inhibitor: These drugs can reduce the clearance of Sildenafil, the active ingredient of Welgra 100.
- CYP3A4 inducers: These may lower peak concentrations and AUC of Welgra 100.
- Ritonavir, Saquinavir, and Bosentan: Unlike the above drugs, these can increase peak concentrations and AUC of Welgra 100
- Nitrites, organic nitrates, and nitric oxide: These increase the risk of hypotension.
- Alpha-blocking drugs: These can lead to symptomatic hypotension.
Grapefruit juice: It may increase the plasma concentration of Welgra 100.
7. Notes when using Welgra 100
Welgra 100 is not prescribed for women, pregnant women, and breastfeeding women.
This medication is available by prescription only. It is important to be aware of any cardiovascular condition when treating erectile dysfunction with Welgra 100. Individuals who are advised against sexual activity due to health issues or other existing diseases should not use this medication.
Patients with left ventricular outflow obstruction, multiple system atrophy syndrome, or ischemic optic neuropathy should carefully consider the use of Welgra 100. If a patient experiences a sudden loss of vision or a decrease or loss of hearing while taking Welgra 100, they should stop taking the medication immediately and seek medical attention for evaluation and treatment.
Patients who experience erections lasting longer than 4 hours and do not improve with self-treatment should seek medical attention immediately for timely invention.
It is important not to combine Welgra 100 with other PDE5 inhibitors or other medications for erectile dysfunction.
The following individuals should be careful when using Welgra 100:
- Those with blood clotting disorders or acute peptic ulcer disease.
- Individuals with anatomical deformities of the penis or conditions that are more likely to cause painful erections.
- Patients with retinitis pigmentosa or disorders related to the phosphodiesterase gene in the retina.
Here is all the essential information that users of Welgra 100 need to know for treating erectile dysfunction. With this information, patients can use the medication effectively and minimize the risk of unexpected side effects.
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