This is an automatically translated article.
The article was professionally consulted by Specialist Doctor I Do Van Manh - Emergency Resuscitation Doctor - Emergency Resuscitation Department - Vinmec Ha Long International HospitalBlood clotting is a protective mechanism in the body to prevent bleeding. Our body always needs a balance between two systems: clotting and preventing blood clotting. If these two systems are out of balance, the blood vessels will become blocked and bleed. So how long does normal blood clotting take?
1. What is the normal blood clotting time?
To determine the clotting time, your doctor will order you to do some blood clotting tests. Each test method may give different results on clotting time.The following are some methods of blood clotting tests:
1.1. Blood clotting time test method When blood leaves the body, blood vessels will not be exposed to non-endothelial factor, the clotting process is induced by the activation of endogenous factors. The time period when blood leaves the blood vessel until a clot is formed is called the clotting time.
When performing a clotting time test, a normal blood clotting time result is between 8-12 minutes. If the time is prolonged, it may be a manifestation of a clotting disorder, if it is reduced, it may be the presence of factors that inhibit clotting or decrease factors.
More than 15 minutes is considered prolonged clotting time.
1.2. Blood clot test method Blood clots when it leaves the vessel wall and turns solid through the formation of fibrin fibers. The visible components will be embraced by the fibrin networks and then contract to form a clot that separates from the serum.
The blood clot will be placed in a test tube with a water thermostat of 37 degrees Celsius. After 3 hours of separation from the test tube, the clot will completely shrink if normal.
In the case of platelet factor or fibrinogen abnormalities, the clot may contract incompletely or not at all.
1.3. Prothrombin test method This is a method to investigate the exogenous coagulation pathway. Prothrombin (PT) mainly shows the coagulation activity of factors involved in the exogenous coagulation pathway.
If PT is normal, clotting time is 10-14 seconds.
Nếu PT bình thường thì thời gian đông máu là từ 10 -14 giây
If Thromboplastin is normal, the clotting time will last about 30-40 seconds.
1.5. Thrombin Time Test Method This method is used to evaluate the overall coagulation pathway.
Normal clotting time is 14-16 seconds.
2. Causes leading to abnormal blood clotting time
Tình trạng máu đông chậm hơn có thể gặp ở đối tượng bệnh nhân xơ gan
Subjects taking Heparin . People with cirrhosis of the liver. Coagulation factors are deficient. Subjects using Warfarin. Presence of Lupus inhibitory factor. Faster blood clotting may be due to a deficiency of anticoagulants leading to increased fibrinogenesis, causing hypercoagulability, thrombosis.
So is blood clotting dangerous? Blood clots rapidly in the early stages, symptoms are usually very mild, but when hypercoagulability occurs, it can lead to disability, even death. Therefore, the phenomenon of rapid blood clotting is very dangerous, should not be subjective.
Testing to know the clotting time of each patient is very important. Based on the blood clotting time, the doctors will know the exact blood clotting status of each patient to give the right treatment for each subject.
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