Surbex Z is indicated for use in cases of zinc deficiency, as well as deficiencies in B vitamins and vitamin C. The medication is administered orally during treatment. However, in some specific cases, it may cause side effects such as rashes, anaphylactic shock, or a burning sensation.
1. Pharmacodynamics of Surbex Z
Zinc deficiency can cause impaired growth in the body. This may be due to a lack of essential micronutrients from excessive dieting, aging, alcohol dependence with cirrhosis, malabsorption disorders, or cystic fibrosis. Additionally, individuals receiving intravenous nutritional solutions may not be adequately supplied with minerals or vitamins as per recommended daily requirements.
Pharmacodynamics of Surbex Z:
- The B-complex vitamins in Surbex Z are absorbed via an active transport mechanism, rapidly excreted, and do not accumulate in the body.
- Calcium pantothenate is rapidly absorbed from the gastrointestinal tract and distributed to cells throughout the body.
Vitamin C is rapidly absorbed from the intestines.
Preclinical Safety Data for Surbex Z Compounds:
- Vitamin C generally does not cause toxicity unless taken in unusually high doses of 4 to 12 grams. At high doses, urine may become acidified, and some chronic urinary tract infections may lead to the formation of urate and cystine crystals.
- Vitamin E has a good body response. High doses may cause gastrointestinal disturbances or fatigue.
- Calcium pantothenate has not shown any toxicity issues under normal conditions. However, a dose of 10g/kg orally in rats or 0.91g/kg by injection may cause acute toxicity. In a study with 15 people receiving 100mg of pantothenate intravenously (as calcium or sodium salt), no significant changes were noted in blood pressure, pulse, temperature, or respiratory rate.
- Vitamin B1 administered intravenously at doses of 125mg/kg may cause toxicity in rats and 350mg/kg in dogs. However, when administered orally, the toxic dose may be up to 40 times higher than that for intravenous administration.
- Vitamin B2 is generally non-toxic. No toxicity was observed in rats with doses up to 10g/kg or in dogs at 2g/kg.
- Vitamin B6, at high doses of 3 to 4g/kg, may cause seizures or death in animals. However, lower doses typically do not exhibit obvious toxic effects.
- Vitamin B12 does not cause toxicity at doses of 1.6g/kg when injected intravenously in rats. Clinically, vitamin B12 injections are generally painless and do not cause local reactions. High-dose subcutaneous or intravenous administration does not show significant adverse effects.
2. Dosage and Administration of Surbex Z
Surbex Z is used to support the treatment of B-vitamin, C-vitamin, and zinc deficiencies. Surbex Z can be taken orally but requires a doctor's prescription. For adults, the recommended dosage is 1 tablet per day. The safety and appropriate dosage for children have not been established, so medical advice is necessary.
Before using Surbex Z, it is important to read the instructions carefully. Any questions or concerns should be discussed with a doctor for further guidance.
If you accidentally overdose, you should seek emergency medical assistance immediately or go to the nearest medical facility. It is also important to bring a list of all medications, both prescribed and over-the-counter, to help the doctor assess the situation. Emergency management of Surbex Z overdose should focus on symptom management, with supportive measures as needed.
If you miss a dose, take it as soon as you remember. If the next dose is near, skip the missed dose and continue with the regular schedule.
3. Potential Side Effects of Surbex Z
Surbex Z generally serves as a supplement for micronutrient deficiencies, but some individuals may experience side effects, including:
-Allergic reactions or rash
-Anaphylactic shock
-Immune-related reactions
-Gastrointestinal issues such as heartburn, bloating, abdominal cramps, nausea, diarrhea, and loss of appetite
-Hepatic issues such as abnormal liver function tests or increased bilirubin levels
-Metabolic or endocrine issues such as bright yellow urine or oxalate metabolism disturbances
If side effects occur, discontinue use and consult a doctor. In case of an emergency, take the patient to the nearest healthcare facility for proper management.
Precautions:
-Surbex Z is contraindicated in individuals with known hypersensitivity to its components, and it should not be used in children or pregnant women due to the risk of birth defects associated with high doses of vitamin B6.
-Surbex Z may interact with levodopa (a decarboxylase inhibitor) and with substances such as niacinamide and alcohol, which could lead to alcohol poisoning or lactic acidosis.
-Surbex Z should be stored at room temperature, away from moisture and light to prevent degradation. Keep it out of reach of children and pets.
Surbex Z is indicated for the treatment of zinc, B-vitamin, and C-vitamin deficiencies. To ensure safety and effectiveness, it should only be taken as prescribed by a doctor or pharmacist.
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