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Surbex Z is indicated for use in cases where the patient is deficient in zinc, vitamins B and C. The drug is used orally during treatment. However, in some specific cases, the drug can cause side effects such as an itchy rash, anaphylaxis or a burning sensation.
1. Pharmacodynamics of the drug Surbex Z
When there is a zinc deficiency, the body will grow slowly. The cause may be micronutrient deficiency due to excessive diet, the elderly, alcoholics with liver cirrhosis or malabsorption disorders, cystic fibrosis. In addition, there are people who use nutritional solutions through the intravenous line but are not provided with the recommended daily intake of minerals or vitamins.
Pharmacodynamics of Surbex Z:
Vitamin B-complex in Surbex Z is absorbed by active transport, is eliminated quickly and does not accumulate in the body. Calcium pantothenate is rapidly absorbed from the gastrointestinal tract and distributed to the cells of the body. Vitamin C is rapidly absorbed from the intestinal tract. Preclinical safety data for the compounds in Surbex Z:
Vitamin C is not expected to be essentially toxic unless taken in unusually high doses of 4 to 12 grams. With this high dose, it is possible that the urine will be acidified, and some chronic urinary tract infections may cause precipitation of urate and cystine stones. Vitamin E is reported to have a good response to the body. When used in high doses can cause gastrointestinal upset or fatigue. Calcium pantothenate has basically not found any toxicity problem. However, when using an oral dose of 10g/kg, it can cause acute poisoning in rats or using an injection with a dose of 0.91g/kg. According to the results of an observational study in 15 people injected intravenously with a dose of 100 mg pantothenate in the form of calcium or sodium salts, no significant changes in blood pressure, pulse, temperature or respiratory rate were observed. Vitamin B1 when administered intravenously at a dose of 125mg/kg can be toxic to rats or dogs using a dose of 350mg/kg. However, when used orally, the toxic dose can be 40 times higher than that of the parenteral route. Vitamin B2 is almost non-toxic. When tested with 10g/kg for rats and 2g/kg for dogs, no toxicity was found. Vitamin B6 when used in high doses from 3 to 4g/kg can cause convulsions or death in animals. However, when using lower doses, the effect may not be apparent. Vitamin B12 was not toxic at a dose of 1.6g/kg when administered intravenously in rats. In the clinical field, vitamin B12 injection is painless and does not cause reactions at the injection site. If vitamin B12 is injected under the skin and veins with high doses, there are no side effects.
Thuốc Surbex Z được chỉ định sử dụng trong trường hợp người bệnh thiếu vi chất kẽm
2. Dosage and how to use Surbex Z
The use of Surbex Z can be said to support the treatment of vitamin B, C and zinc deficiency. Surbex Z can be taken orally, but requires a doctor's prescription. For adults, can take 1 tablet per day. As for children, there are currently no studies to prove a safe dose, so it is necessary to consult a doctor.Moreover, before using Surbex Z, you need to read the instructions for use carefully and if you have any questions or doubts, you must notify your doctor so that you can find out the cause and take measures.
When using Surbex Z, if you overdose and an emergency occurs, you can call an ambulance or immediately go to the nearest local medical facility where you live for timely treatment. In addition, the patient also needs to write down or bring a list of drugs ever used, including prescription and non-prescription so that the doctor can find out the cause for proper treatment. The emergency management of Surbex Z overdose should focus on the symptoms of the situation, and apply supportive measures in case of need.
In case you forget to take the medicine according to the prescribed dose, you can take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the prescribed time.
Thuốc Surbex Z được sử dụng bằng đường uống khi điều trị
3. Possible side effects when using Surbex Z
In general, the effect of Surbex Z is to supplement the micronutrients that the body lacks. However, in some cases, side effects may occur when using this drug such as:
Allergic reaction or rash; Anaphylaxis; Immune system related reactions; Gastrointestinal side effects: Burning or belching, abdominal cramps, vomiting, diarrhea and loss of appetite. Side effects related to the hepatobiliary system: Abnormal liver function tests, hyperbilirubinemia; Side effects related to metabolism and endocrine with urine turn bright yellow or may cause oxalate metabolism disorders.... In case patients experience side effects of Surbex Z, it is necessary to discontinue use. use and notify your doctor. In an emergency situation, it is necessary to take the patient to the nearest medical facility for timely treatment.
A few notes when using Surbex Z:
Surbex Z is contraindicated in some cases of hypersensitivity to the drug's ingredients or children and pregnant women. Because the use of drugs with high doses of vitamin B6 can be associated with birth defects in babies. In addition, the ingredients of the drug may interact with levodopa - a decarboxylase inhibitor or medicine that interacts with the components niacinamide and alcohol, alcohol poisoning or lactic acidosis. Surbex Z should be stored at room temperature, avoiding mold or light damage. Medicines should be kept out of reach of children and pets. Surbex Z is indicated in case the patient lacks micronutrients such as zinc, vitamins B and C. To ensure safety and effectiveness, the patient needs to take the drug as prescribed by a doctor or pharmacist.
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