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Methylene blue belongs to the group of active ingredients for first aid and detoxification. The drug is highly effective in the treatment of impetigo, pyoderma, and viral skin infections such as herpes simplex. We can encounter methylene blue drugs in the form of: tablets, injections, 1% external solution or milian solution.
1. General information about drugs
Methylene Blue (Methylene Blue) was first prepared by Heinrich Caro in 1876. After that the drug was widely used and popularized, now it is in an important and essential drug group.
The drug is highly effective in disinfecting, detoxifying, making dyes, treating some common skin infections. This drug is quite benign, non-toxic, in case of accidental ingestion, it is not dangerous. The drug is absorbed from the gastrointestinal tract and excreted in the urine, the waste is also colorless.
In addition to the antiseptic effect, methylene blue also has the effect of staining tissues. The drug breaks down the virus molecule when exposed to light by irreversibly binding to the viral nucleic acid. As a result, in the treatment of local viral infections, the drug also promotes its use as treatment of herpes simplex, treatment of impetigo, pyoderma; urinary tract infection.
Methylene blue is absorbed from the gastrointestinal tract. Through urine and bile, methylene blue is eliminated and is mostly colorless. Urine only turns green or blue when exposed to air.
The drug is not used in the following cases:
Patients with methemoglobinemia People with cyanide poisoning
2. Side effects of drugs
Patients may experience some side effects of the drug such as:
Encounter some symptoms related to the gastrointestinal tract such as: nausea, dizziness, abdominal pain... When using the drug for a long time can cause anemia Some interactions can occur when using the drug with some other drugs such as: iodide, dichromate, some alkalis, other oxidizing and reducing agents Some other side effects such as: pain headache, fever, anemia, hemolysis, blue skin
3. How to use Methylene Blue?
Methylene Blue is used through 2 routes: injection and topical application. Patients should note a number of ways to use the drug as follows:
Using drugs by injection: Before using the drug through injection, it is necessary to dilute it, it can be diluted with saline with a concentration of 0.9% . Until the 0.05% concentration of Methylene Blue solution is mixed, it can be used safely when injecting.
When injecting, it is necessary to inject slowly from 1–2 mg/kg body weight. The next dose is about 1 hour after the previous dose, in case the patient needs more injections.
Use the drug when applied topically: Before using the drug, carefully read the instructions for use and ask the doctor for the necessary information. When using sugar methylene blue, apply alcohol to disinfect and clean the area of application on the skin. Dot and apply the medicine gently on that area of skin.
How to apply Methylene Blue orally: For those who use Methylene Blue tablets to take orally, use a dose of 150-300 mg/day (except in urgent cases). When taking oral Methylene Blue, it should be taken with plenty of water for easy digestion, to avoid digestive disorders and difficulty in urination.
4. Be careful when using drugs
Patients when using Methylene Blue should consult a doctor and strictly follow the instructions and prescriptions of the doctor for the best treatment process.
The drug is not used for pregnant and lactating women Do not use for people with glucose - 6 phosphate dehydrogenase deficiency because it can cause acute hemolysis. The drug is only used for a short time, not for a long time. People with kidney failure should also not take methylene blue
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