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Roswera belongs to the group of cardiovascular drugs that are made in the form of film-coated tablets. The main ingredient of Roswera drug is rosuvastatin, which is indicated for the treatment of primary hypercholesterolemia, dyslipidemia, homozygous hypercholesterolemia... However, during treatment with Roswera, some side effects may occur. Unwanted side effects such as headache, dizziness, nausea, constipation ... Therefore, patients should learn carefully before using.
1. Mechanism of action of the drug Roswera
Roswera contains rosuvastatin - a selective and competitive inhibitor of HMG-CoA reductase - an enzyme that catalyzes the conversion of 3 hydroxy 3 methylglutaryl coenzyme A to cholesterol precursor mevalonate. The main site of action of this compound is the liver, the target organ that helps lower cholesterol in the body. In addition, this compound also increases the number of LDL receptors on the cell surface in the liver and increases the absorption and catabolism of LDL and inhibits the synthesis of VLDL in the liver quite effectively.2. Indications and contraindications for the use of Roswera
What does Roswera do? Roswera is indicated in the treatment of primary hypercholesterolemia including heterozygous familial hypercholesterolemia or mixed dyslipidemia with type IIB. In addition, Roswera can be used in the treatment of homozygous familial hypercholesterolemia.
3. Dosage and how to use Roswera
Roswera is used orally with a recommended starting dose of 5 to 10mg and used once a day. If necessary, the dose can be adjusted every 4 weeks and according to the doctor's instructions. Roswera 40mg dose is used when severe hypercholesterolemia is at high risk of cardiovascular disease and the treatment goal at 20mg is not achieved. These patients must be monitored regularly.
For patients with a history of liver disease, caution should be taken when using Roswera, because patients may have rhabdomyolysis such as renal failure, hypothyroidism, history of muscle toxicity due to HMG inhibitors. CoA. Or in cases of alcoholism, there are conditions that cause increased drug levels in the blood
Should not be used when infection or hypotension, major surgery, trauma, electrolyte disorders, endocrine, severe metabolism.
Note: The above recommended therapeutic dose is for reference only. Therefore, before using Roswera, patients need to follow the doctor's instructions.
4. Management of missed dose and overdose Roswera
If you miss a dose of Roswera, use it as soon as you remember. However, if the interval between the missed dose of Roswera and the next dose is too close, skip the missed dose. Patients should not double the dose of Roswera, because it can cause an overdose. To overcome the situation of missing doses of Roswera, patients can set alarms or ask relatives to remind them.
In case of accidentally using Roswera drug in excess of the prescribed amount and some unwanted signs appear, the relatives need to take the patient to the emergency hospital immediately.
5. Side effects when using Roswera
Roswera may cause some unwanted side effects during treatment. However, with each case, the side effects of Roswera may vary from mild to severe.
Some common side effects caused by Roswera include: nausea and vomiting, headache, muscle pain, ... These side effects can occur at the beginning of treatment or after increasing the dose of the drug. Roswera. Usually, the side effects from Roswera can be transient or subside over time.
However, in some cases Roswera can cause serious unwanted side effects with rare reactions. These reactions may appear within minutes of using Roswera or longer within a few days. When the occurrence of serious side effects such as: rash, urticaria, disorders of the musculoskeletal system, connective tissue and bones, muscle wasting, weakness, increased transaminase... the patient should stop using Roswera and go to the hospital. medical facility for immediate medical assistance.
Some notes in the process of using Roswera:
For pregnant and lactating women, caution should be exercised when using Roswera. Patients should be advised to use Roswera from their doctor, and carefully analyze the benefits and risks before using the drug. Roswera may change how it works and increase its side effects. Therefore, to avoid drug interactions, the patient should provide the doctor with a list of previously used drugs, including prescription and non-prescription drugs, herbs,... Medicines that affect alertness user's. Therefore, if the patient often has to perform the work of operating machinery or driving a car that requires high concentration, care should be taken when using Roswera. Use caution when using Roswera for subjects with liver dysfunction. Above is important information about Roswera drug, patients should carefully read the instructions for use and use according to the dose prescribed by the doctor to achieve the best effect.