Invel contains 2 main ingredients, Miconazol nitrate and Metronidazole, which are effective in treating vaginal candidiasis and vaginitis caused by many reasons.
1. What is Invel?
Invel is a vaginal suppository, prepared in tablet form. Each Invel tablet contains the following ingredients:
- Metronidazole 500mg.
- Miconazole nitrate 100mg.
- Excipients are just enough for 1 Invel tablet.
2. Effects of Invel
Effects of the main ingredients in the Invel formula:
- Antibacterial and antifungal effects, treating Trichomonas.
- Metronidazole: Has a broad spectrum, effective on most anaerobic bacteria and protozoa. However, this active ingredient does not affect fungi, viruses, and aerobic bacteria.
- Miconazol: Has antibacterial and antifungal effects.
With the above effects, Invel is indicated in the following cases:
- Invel is indicated for the treatment of vaginal candidiasis;
- Vaginitis is caused by Trichomonas, bacteria, or mixed infections.
3. How to use and dosage of Invel
How to use Invel:
- Insert Invel deep into the vagina while lying down. Can be inserted in the morning or evening before going to bed.
- Invel is for vaginal use only, do not swallow.
Instructions for Invel:
- Do not use Invel for children.
- Insert 1 Invel tablet in the evening for 14 days or 1 tablet/time, twice a day in the morning and evening for 7 days.
- In cases of vaginitis resistant to other treatments, the disease recurs, it is recommended to insert Invel twice a day.
How to manage the missed dose of Invel:
- Missed dose: Take a replacement dose of Invel as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not take 2 Invel tablets at the same time to make up for a missed dose.
4. Contraindications to using Invel
Do not use Invel in the following cases:
- Allergy to the ingredients of Invel.
- Pregnant women in the first 3 months.
- Porphyrin metabolism disorder.
- Severe liver dysfunction.
- Epilepsy.
5. Undesirable effects of Invel
Invel may cause the following side effects:
- Headache and fatigue.
- Itching, burning, or hypersensitivity reactions such as rash.
- Lower white blood cells;
- Loss of coordination or neurological changes.
- Convulsions;
- Diarrhea, constipation, loss of appetite.
- Vomiting and nausea;
- Abdominal pain;
- Changes in taste;
- Dry mouth, metallic taste.
Vaginal burning or itching may occur when using Invel for the first time. If any unusual signs occur, contact a doctor immediately or go to the nearest medical facility for timely treatment.
6. Drug interactions
Interactions may occur when using Invel at the same time as the following drugs:
- Alcohol and Disulfiram: Using Invel together causes effects on the nervous system.
- Invel increases the effectiveness of anticoagulants when used at the same time.
- Phenytoin, Phenobarbital.
- Invel increases Lithium toxicity.
- Cimetidine, Astemizole and Terfenadine.
To ensure safety, inform doctor about any medications, dietary supplements, or medical history to consider possible interactions.
7. Notes when using Invel and how to store it
- Pregnant women should not use Invel in the first 3 months of pregnancy, consult adoctor before use. Metronidazole is excreted in breast milk, so do not use Invel while breastfeeding or do not breastfeed 24 - 48 hours after the mother takes the drug.
- Invel does not affect the ability to drive and operate machinery.
- Read the instructions for Invel carefully before use.
- Do not drink alcohol while taking Invel, at least 24-48 hours after taking the drug.
- If the patient is infected with Trichomonas, the sexual partner must also be treated.
Preserving Invel:
- Store Invel in a cool, dry place, away from direct sunlight.
- Keep Invel out of reach of children.
The above is information on the uses, dosage, and precautions when using Invel. To ensure your health and maximize the effectiveness of treatment, you need to use Invel according to doctor's instructions.
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