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Amoksiklav is often indicated for use in the treatment of infections caused by bacteria, such as respiratory infections, abdominal infections, bone and joint infections,...
1. What is Amoksiklav?
Amoksiklav is an antibiotic capable of killing bacteria that cause infections. The drug is prepared in the form of film-coated tablets, packed in a box of 2 blisters x 5 tablets. For Amoksiklav 625mg, there will be the following specific active ingredients:
Main active ingredients: Amoxicillin (as trihydrate salt) 500mg and clavulanic acid (clavulanate potassium salt) 125mg. Other excipients: Crospo-vidone, Colloidal silicon dioxide, Crosslinked carboxymethylcellulose sodium, Microcrystalline cellulose, Magnesium stearate, Ethylcellulose, Hydroxypropylcellulose, Titanium dioxide, Polysorbate, Talc and Triethylcitrate. In addition, the drug Amoksiklav is also prepared in a larger concentration. Specifically, the drug Amoksiklav 2x 1000mg or the drug Amoksiklav 1g (box of 10 tablets). Each tablet contains Amoxicillin as amoxicillin trihydrate 875mg and clavulanic acid as potassium clavulanate 125mg, in a ratio of 7:1.
2. Indications and contraindications to the use of Amoksiklav
2.1. Indications for use of Amoksiklav Amoksiklav medicine Amoksiklav 625mg is an antibiotic with bactericidal ability, usually indicated for use in both children and adults to treat the following infections:
Respiratory tract infections:
Respiratory tract infections , gynecology, urology, soft tissue, skin. Intra-abdominal infection or intra-abdominal superinfection after surgery. Postoperative infection or sepsis. Bone or tooth infections. Sinus or middle ear infection. Infections with Gram (-) and Gram (+), anaerobic bacteria sensitive to the drug. Goosebumps or lower oranges . Cholangitis, peritonitis, osteomyelitis , insect bites and cholecystitis. Prophylaxis of surgical infections. 2.2. Contraindications to the use of Amoksiklav Do not use Amoksiklav in the following cases:
Patients with a history of allergic reactions to clavulanic acid, Amoxicillin, Penicillin or any of the active ingredients in the drug. If you have ever had a severe allergy or hypersensitivity to any antibiotic, symptoms may include facial swelling, skin rash, or neck swelling. People with a history of liver dysfunction, jaundice when using antibiotics. People with infectious mononucleosis or lymphoma.
3. Dosage and instructions for using Amoksiklav
3.1. Dosage of Amoksiklav Amoksiklav dosage will be determined specifically based on the age and health status of the patient, including:
Adults and children from 12 years of age and older (weighing about 40kg): Oral: Oral Usual dose is one tablet 625mg twice daily for mild infections, one tablet 1000mg twice daily for severe infections. Amoksiklav is not recommended for use in children under 12 years of age due to the lack of specific safety data. Dosage for treatment of dental infections: 625mg x 2 times/day, continuously used for 5 days. The maximum daily dose of clavulanic acid (as potassium salt) is 600mg for adults and 10mg/kg body weight for children. Meanwhile, the maximum daily dose of Amoxicillin for adults is 6g and for children is 45mg/kg body weight. 3.2. Instructions for use of Amoksiklav When using Amoksiklav, patients should swallow the tablet whole with a full glass of water before starting the main meal. The drug is divided according to the dosing line on the side of the drug, making it easier for patients to use the drug.
Patients should take Amoksiklav with the same number of doses throughout the day, at least 4 hours apart and avoid taking 2 doses in the same hour. Also, avoid taking Amoksiklav for more than 2 weeks. If the infection does not seem to be improving, the patient needs to be re-examined to find out the cause.
3.3. How to deal with an overdose or missed dose of Amoksiklav *In case of an overdose of Amoksiklav:
When taking an overdose of Amoksiklav, the patient may experience an upset stomach (diarrhea, nausea or vomiting) or an upset stomach. convulsions. If the above symptoms appear after taking an overdose of Amoksiklav, the patient should notify the doctor immediately for timely treatment.
*If you miss a dose of Amoksiklav:
If you miss a dose of Amoksiklav, you need to take it as soon as you remember. However, avoid taking the next dose too soon, but wait about 4 hours before taking the next dose.
4. Some side effects of the drug Amoksiklav
During the use of Amoksiklav 625mg or 1g, patients may experience some of the following side effects:
Digestive disorders, diarrhea in both adults and children (Very common). Thrush (a yeast infection in the vagina, in the skin folds, or in the mouth). Stomatitis, pseudomembranous enteritis with severe diarrhea, vaginitis, cholestatic jaundice or hepatitis. Feeling nauseous, especially when taking high doses of the drug. Allergies, bronchospasm, Quincke's edema or anaphylaxis. Thrombocytopenia, leukemia or eosinophilia. Severe diarrhea with blood in the stools, white stools, cloudy urine, yellowing eyes, indigestion, pain, or urinating less than usual (the drug should be stopped). When experiencing any of the symptoms mentioned above, the patient needs to quickly go to the nearest clinic or medical facility for diagnosis and correction.
5. Some important notes when using Amoksiklav
Patients need to discuss carefully with their doctor before using Amoksiklav if they have the following conditions:
Having a fever. Have a history of allergies. Are being treated for kidney or liver problems, eg liver/kidney dysfunction, liver/kidney failure. Cholestatic jaundice, mononucleosis, leukemia. Have a history of a rash on the face, swelling of the larynx, or difficulty breathing after taking any medication. Have asthma. There is a false-positive result on a urine or blood test. Are using drugs containing K. Phenylketouria. Rarely transfuse water. During the use of Amoksiklav, patients also need to be careful about the following:
The doctor can conduct an exact test for the type of bacteria causing the infection to give the right prescription. Amoksiklav can worsen some of a patient's existing health conditions and even cause serious side effects, including seizures, allergies, and inflammation of the large intestine. This medicine may affect the results of blood tests (eg, liver function tests or red blood cell status tests) and urine tests. If you are pregnant, suspect that you may be pregnant, plan to become pregnant or are breast-feeding a baby, please inform your doctor for specific advice before deciding to take the drug. Amoksiklav may interact with the following medicines:
Gout medicine (Allopurinol), which may increase the risk of allergies. Probenecid (the doctor can adjust the dose of Amoksiklav). Medicines that prevent the formation of blood clots such as Warfarin. Medicines for cancer/rheumatism such as Methotrexate. Medicines that help prevent rejection of new organs such as Mycophenolate mofetil. In order to minimize the risk of drug interactions, patients should inform their doctor about any medications they are currently taking. This includes over-the-counter drugs, prescription drugs, health supplements, herbs or multivitamins. Doctors can review and assess the risk of drug interactions to make decisions to adjust the dose or replace the new drug for the patient.
In order for Amoksiklav to always achieve the best quality and avoid damage, patients should adhere to the following drug storage instructions:
Store the medicine in a cool, dry place and avoid high humidity. Store the medicine in a high place, out of sight and reach of small children. Avoid using the medicine after the expiration date printed on the label. Store medicines in their original packaging to ensure they do not become moldy or come in contact with agents that spoil the medicine. In order to achieve high treatment effectiveness and minimize the risk of side effects, patients need to strictly follow the medication instructions recommended by the doctor.
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