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Exforge 10mg/160mg drug is manufactured as a combined oral tablet with the main ingredients being amlodipine and valsartan. It is commonly used to treat essential hypertension and is indicated in adults whose blood pressure is not adequately controlled with amlodipine or valsartan alone.
1. Uses of the drug Exforge 10/160
Exforge 10/160 drug consists of two main ingredients amlodipine 10mg and valsartan 160mg, has the following specific uses:
Amlodipine: belongs to a group of calcium antagonists that prevent calcium ions from crossing the membrane into the myocardium and vascular smooth muscle. , thereby relaxing vascular smooth muscle, reducing peripheral vascular pressure and lowering blood pressure. Valsartan: belongs to the class of angiotensin II antagonists that help lower blood pressure. At oral therapeutic doses, the drug has antihypertensive effect within 2 hours after oral administration, peaks after 4-6 hours, and antihypertensive effect persists for 24 hours. Amlodipine and valsartan in Exforge 10/160 help lower blood pressure more strongly than when using either active ingredient alone, thereby increasing the effectiveness of treatment.
Exforge 10/160 is indicated primarily in adult patients whose blood pressure is not adequately controlled with amlodipine or valsartan as monotherapy.
2. Dosage of Exforge 10/160
Exforge 10/160 is usually used as an oral tablet, patients should swallow the tablet whole with water, do not chew or crush the tablet to avoid reducing the bioavailability of the drug. The effect of the drug does not depend on food, so taking Exforge 10/160 at the time before or after eating is okay.
The recommended dose of Exforge 10/160 is 1 tablet per day at a fixed interval to ensure maintenance of blood levels. If the patient misses a dose, only take it when it is far from the time of the next dose, absolutely do not double the indicated dose for the purpose of making up for the dose. Overdose can cause symptoms such as excessive drop in blood pressure, dizziness or excessive peripheral vasodilation causing tachycardia, even shock and death.
3. Side effects of Exforge
In some cases when using the drug Exforge 10/160, it may cause unwanted effects such as:
Edema Fatigue, weakness Nasopharyngitis Influenza Dizziness Tachycardia Drowsiness Palpitations Disorders Digestive: diarrhea, nausea, dry mouth Postural hypotension Back pain, joint pain Cough, sore throat,... Erectile dysfunction Increased sweating Diarrhea, polyuria Contraindications of Exforge 10 /160 includes:
Hypersensitivity to any component of the drug Patients with severe liver failure, cholestasis or cirrhosis Women in the first and third trimesters of pregnancy Severe renal failure or on dialysis Children under 18 age
4. Drug interactions with Exforge
When using Exforge 10/160 together with the following drugs may cause adverse reactions, specifically:
Potassium supplements, potassium-sparing drugs: excessive hyperkalemia NSAIDs have May reduce the antihypertensive efficacy Exforge 10/160 should be used with caution in pregnant and lactating women:
Because Exforge 10/160 contains valsartan, an angiotensin II antagonist, it has an adverse effect. bad for the fetus, especially in the last 3 months or the first 3 months of pregnancy. The drug has the potential to cause stillbirth, spontaneous abortion, low amniotic fluid, and other birth defects. Lactation: There have not been specific studies on the ability of the drug to be excreted in human milk, but it is still recommended not to use the drug in nursing women. Once you understand the use of Exforge 10/160, the patient should strictly follow the instructions to achieve the most effective treatment. If you have any further questions, you can consult your doctor.
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