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One of the drugs used to treat peptic ulcers is Sucrate gel. So what effect does sucrate gel have and how should it be used in peptic ulcers?
1. What does sucrate gel do?
Sucrate gel contains sucralfate 1g. The use of sucrate gel is to treat peptic ulcers, acute and chronic gastritis, and esophageal ulcers. In addition, this drug has also shown to be effective in preventing stomach ulcers, stress ulcers or supporting the treatment of gastroesophageal reflux disease.
Ingredients in each 5ml pack of Sucralfate gel will contain 1g of Sucralfate in the form of oral suspension. In terms of packaging, each box contains 30 packs of sucrate gel.
Sucrate gel is a physical form of the active ingredient sucralfate and was first patented by Lisapharma, Italy. The specific surface area of Sucrate gel is twice as high as that of conventional sucralfate powder and according to research data, it has a very strong adhesion to the gastric mucosa. Thanks to this property, the use of Sucrate gel is very effective against ulcers. Mechanistically, sucralfate coats the ulcer surface through a complex with proteins (such as albumin and fibrinogen) present on the damaged mucosa, which forms a protective barrier and prevents attack. of acids, gastric juices and bile salts. In addition, Sucrate gel stimulates the production of prostaglandin E2 and gastric mucus.
Regarding the pharmacokinetics, after oral administration, only a very small amount of sucrate gel is absorbed through the gastrointestinal tract and excreted in the urine.
2. Dosage of Sucrate gel
The usual dose of Sucrate gel is 1 sachet x 2 times/day. Sucrate gel should be taken on an empty stomach, one hour before breakfast and before bedtime. Treatment until the ulcer is completely healed (through gastroesophageal endoscopy results), the average duration of treatment lasts from 4-8 weeks.
In maintenance therapy, the daily dose of Sucrate gel is halved (only 1 sachet/day in the evening). The medicine can be taken with a sip of water or another drink.
Note, the above dose of Sucrate gel is for reference only because the exact dose depends on many factors such as physical condition and disease progression. To get the right dose, the patient should consult a doctor or healthcare professional.
Some notes on the dosage of Sucrate gel:
When using an overdose, in case of emergency, call the nearest medical emergency or go to the nearest local health station; If you forget to take any dose, take it again as soon as possible. However, if it is almost time for the next dose of Sucrate gel, skip the missed dose and take the next dose of Sucrate gel at the usual time. Normally, double should not be used to compensate.
Liều thông thường của Sucrate gel là 1 gói x 2 lần/ngày
3. Contraindications of Sucrate gel
Sucrate gel is contraindicated for use in cases of known allergy or hypersensitivity to the ingredients in the drug; Sucrate gel contains aspartame and should not be used by people with phenylketonuria; Children under 12 years old; During treatment, do not use Sucrate gel with tetracycline antibiotics at the same time because the formation of salt complexes will reduce the effect of antibiotics; Sucrate gel can reduce the bioavailability of many other drugs, so patients should take it at least 2 hours before taking other drugs.
4. Sucrate gel side effects
When using Sucrate Gel for a long time, users may experience some unwanted effects (ADRs) with an unspecified frequency as follows:
Digestive system disorders, including constipation, dry mouth; Nervous system abnormalities, such as dizziness, lightheadedness, insomnia; Side effects on the skin, including itching, rash, or redness. In case of experiencing side effects of Sucrate gel, the patient should immediately stop using it and notify the doctor or go to the nearest medical facility for timely treatment.
During use, patients with a history of renal failure should be cautious when using Sucrate gel for a long time; For women who are pregnant, they should be cautious and only use Sucrate gel in cases where it is absolutely necessary.
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