Uses of Panto Denk 20

This is an automatically translated article.

1. What are the uses of Panto Denk 20?

Ingredients Panto Denk 20 is Pantoprazol 20mg. This is a Benzimidazole derivative, which inhibits gastric acid secretion (thanks to a specific reaction with the proton pump of the parietal cells). The inhibitory potential of the drug depends on the dose and mechanism. In most patients, Panto Denk 20 produces a mild relief of symptoms after about 2 weeks of treatment.
Indication of Panto Denk 20 in the following cases:
Treatment of mild reflux and related symptoms including: heartburn, heartburn, loss of voice,...; Long-term treatment, prevention of recurrence of reflux esophagitis; Prophylaxis of NSAID-induced peptic ulcer disease (nonsteroidal anti-inflammatory drug) in patients at risk of disease due to continued NSAID therapy.

2. Instructions for using Panto Denk 20

Usage: The drug is taken orally. Panto Denk 20 tablets should be swallowed whole with some water, do not chew or crush the tablet.
Dosage:
For adults and children 12 years of age and older: Reflux disease and related symptoms: Use Panto Denk 20 at a dose of 1 tablet/time/day. Symptoms improve within 2-4 weeks of treatment. For esophagitis, take 1 tablet once a day. Symptoms improved within 4 weeks of treatment. If the desired effect is not achieved, use another 4 weeks. When symptoms are mild, take 1 tablet/day; Long-term treatment, prevention of recurrence of reflux esophagitis: The maintenance dose of Panto Denk 20 is 1 tablet/day. The dose may be increased to 2 tablets/day in case of relapse. After a course of treatment with a dose of 2 tablets / day, the dose can be reduced to 1 tablet / day. For long-term treatment, if the treatment is more than 1 year, the doctor's permission is required; Adults: Prevention of peptic ulcers caused by NSAIDs: Take Panto Denk 20 doses 1 tablet/day; Patients with liver failure: The dose of Panto Denk 20 should not exceed 1 tablet/day; Patients with renal impairment and the elderly: No dose adjustment is required; Children under 12 years old: Do not use Panto Denk 20. Note: Dosage of Panto Denk 20 is for reference only. The doctor will base on the patient's condition and disease progression to make the most appropriate indication.
Overdose: When using Panto Denk 20 drug overdose, the patient is gastric lavage, activated charcoal and symptomatic treatment. At the same time, it is necessary to monitor the activity of the heart, blood pressure; If vomiting persists, monitor fluid and electrolyte status.
Missed dose: When a dose of Panto Denk 20 is forgotten, the patient should take it as soon as he remembers. If it is too close to the next dose, skip the missed dose and take the next dose as scheduled.

3. Side effects of Panto Denk 20

When using Panto Denk 20, patients may experience some unwanted side effects such as:
Common: Fatigue, headache, dizziness, skin rash, urticaria, dry mouth, nausea, vomiting, abdominal pain, diarrhea, constipation, muscle pain, joint pain,...; Uncommon: Asthenia, dizziness, insomnia, dizziness, itchy skin, increased liver enzymes,... When experiencing side effects from using Panto Denk 20, the patient should stop taking the drug and notify the doctor immediately. doctor or go to the nearest medical facility for early examination and treatment.

4. Notes when using Panto Denk 20

Contraindications to using Panto Denk 20 for the following cases:
Hypersensitivity to the active ingredients, peanuts, soy or excipients of the drug; Do not use concomitantly with atazanavir. Precautions when using Panto Denk 20:
Patients with liver failure need to check liver enzymes during treatment with Panto Denk 20, especially during long-term treatment. In case of increased liver enzymes, treatment with this drug should be discontinued; Use of Panto Denk 20 for the prevention of NSAID-induced peptic ulcers should be limited to patients on ongoing NSAID therapy and to patients at high risk for gastrointestinal complications. It is necessary to assess the risk on the body factors such as advanced age (over 65 years), history of peptic ulcer, bleeding in the gastrointestinal tract,...; Using Panto Denk 20 may cause malabsorption of vitamin B12. This should be considered, especially in patients on long-term therapy with risk factors for vitamin B12 malabsorption or impaired vitamin B12 stores; The possibility of malignancy should be excluded based on the warning signs of suspicion or the presence of gastric ulcer because the use of drugs may mask symptoms, delay the diagnosis; If symptoms persist with appropriate treatment, other health problems should be considered. Regular monitoring is required in patients treated with Panto Denk 20 for more than 1 year. Should be examined in patients who do not respond to treatment after 4 weeks; For patients taking the drug, there is a risk of hypomagnesemia. Your doctor should check magnesium levels before starting treatment and periodically while taking the drug; Taking Panto Denk 20 at high doses and for a long time (more than 1 year) may increase the risk of hip, spine, and wrist fractures (mostly in the elderly or with many risk factors). Therefore, patients at risk of osteoporosis need to be taken care of carefully, need to take vitamin D and calcium in appropriate doses; The drug contains maltitol, so patients with hereditary problems of fructose intolerance will not be able to use it; Some side effects such as blurred vision, dizziness when taking Panto Denk 20 may affect the ability to drive and use machines; Consult your doctor before taking Panto Denk 20 in pregnant and nursing women.

5. Panto Denk 20 . drug interactions

Some drug interactions of Panto Denk 20 include:
Drugs that reduce the absorption of drugs with pH-dependent bioavailability: Ketoconazole, itraconazole, atazanavir; The drug acts on the liver enzyme system. However, clinical trials have shown no significant interactions between Panto Denk 20 and drugs metabolized by the same isoenzyme; There is a potential for an increase in INR and prothrombin time with concomitant administration of Panto Denk 20 and warfarin. There is a risk of abnormal bleeding and death, so it is necessary to monitor the above indicators when taking 2 drugs; Sucralfate may slow absorption and decrease bioavailability of Panto Denk 20. Therefore, Panto Denk 20 should be taken at least 30 minutes before using Sucralfate. The use of Panto Denk 20 drug should strictly follow all the instructions of the doctor to ensure effective treatment and minimize the risk of dangerous complications.
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