Neurofibromatosis is a rare disease, most cases are benign and not life-threatening, however in some cases of malignant neurofibromatosis, the location of the fibroid tumor is in important organs, causing serious complications or life-threatening.

Brain MRI is considered the most optimal non-invasive method of evaluating the brain. It has special value in diagnosing diseases of the pituitary gland and brain stem. It helps detect and evaluate many diseases or abnormalities of the brain, especially brain tumors due to clear, detailed images, and the ability to observe the brain vessels without injecting contrast agents. Brain pathologies are extremely diverse and complex, so reading the results of brain MRI with a specialist who has a good understanding of knowledge and imaging anatomy must follow a certain order to avoid missing lesions.

Neurofibromatosis is a type of cutaneous neurofibromatosis, commonly found in neurofibromatosis or neurofibromatosis, with lesions such as nodules, lumps, and tumors on the skin. Most neurofibromas are benign but cause loss of aesthetics and affect the patient's daily life.

Neurofibromatosis type 1 (NF1) is the most common and well-understood neurodermatologic disease, with an incidence of approximately 1/3000 to 1 in 4000 individuals. NF1 is an autosomal dominant disease caused by mutations in the NF1 gene located on chromosome 17q11.2. Approximately 50% of NF1 cases are familial, and the remaining cases occur sporadically.

Neurofibromatosis type 2 (NF2) is an autosomal dominant multisystem disease that often leads to the occurrence of multiple benign neuroendocrine tumors, central nervous system tumors, eye abnormalities, and nerve-skin lesions.

Neurofibromatosis is a rare, dominant genetic disease. Most cases of neurofibromatosis are benign and often affect aesthetics. Only a few large tumors compress organs and affect the function of those organs.