Chronic otitis media is a persistent infection in the lining of the middle ear, it is caused by an ongoing inflammatory reaction in the middle ear with granulation tissue formation and is often associated with unresolved bacterial infection or drug-resistant bacteria.

Mastoiditis is a disease that can occur in all subjects, treatment methods include internal medicine and surgery. Medicines to treat mastoiditis are used in cases where surgery is not yet necessary or to help limit the risk of surgery.

Mastoiditis in children is a complication of otitis media, if not treated early can lead to dangerous conditions, even death. Treatment of mastoiditis depends on the specific condition of the child and can be medical or surgical.