This is an automatically translated article.
Article by Pharmacist Nguyen Huy Khiem - Clinical Pharmacist - Faculty of Pharmacy - Vinmec Times City International Hospital
Xatral XL is a commonly used prostate enlargement medication with the active ingredient alfuzosin . Here are some information to keep in mind when patients use Xatral XL.
1. Dosage form of the drug xatral 10mg
Xatral 10mg is available as an extended release (XL - extra long) tablet with a strength of 10mg.
This drug is designed to release the active ingredient slowly (for the purpose of prolonging the duration of action as well as limiting the unwanted effects of the drug). Therefore, the patient should swallow the tablet whole, do not chew - break or crush the tablet before taking it.
2. Indications for xatral xl 10mg
Xatral xl 10mg is indicated for the treatment of symptoms of benign prostatic hypertrophy (such as urinary retention, dysuria, nocturia, urinary incontinence, frequent urination,...). The drug is also indicated for the adjuvant treatment of acute urinary retention due to prostatic hypertrophy requiring catheterization, especially in patients > 65 years of age. In addition, the doctor can also appoint the patient to use xatral xl 10mg to support the expulsion of stones from the urinary tract in some cases of ureteral stones. This is an off-label indication, not found on the product's prescribing information. The mechanism of action of the drug is to selectively antagonize alpha-1 adrenergic receptors (which are abundant in the prostate gland, bladder neck), thereby helping to relax bladder neck smooth muscle, prostate gland, improve speed urine flow as well as symptoms of benign prostatic hypertrophy.Xatral medicine 10mg helps to improve quite quickly the symptoms related to prostate enlargement (within a few days after taking the drug); However, the effect disappears when the drug is stopped.
3. Dosage of xatral xl 10mg
Xatral XL 10mg is used orally. Doctors mainly prescribe an adult dose of 1 tablet of 10 mg/day, taken after meals.
Người bệnh nên sử dụng thuốc xatral xl 10mg theo hướng dẫn
4. Precautions when using Xatral XL
Food helps the drug to be better absorbed (~50% more than taking it on an empty stomach), so it is recommended to use the drug after meals. Noteworthy side effects when using the drug are orthostatic hypotension (drop in blood pressure, dizziness, fainting when changing positions suddenly: lying - sitting - standing). Therefore, when using Xatral XL, patients need to change their position slowly to limit these undesirable effects. Concomitant use of certain drugs such as antihypertensive drugs, nitrates for angina pectoris, etc. may make this undesirable effect more likely to appear. It is necessary to inform the doctor and medical staff that you are taking Xatral XL before participating in eye surgery so that an appropriate discontinuation plan before surgery to reduce the risk of IFIS (intraoperative floppy iris) syndrome is necessary. syndrome – bland iris syndrome). Xatral XL should not be used in patients with moderate to severe hepatic impairment (Child-Pugh class B or C), concomitantly with strong CYP3A4 inhibitors such as ketoconazole, clarithromycin, ritonavir, etc. Because xatral 10mg can cause dizziness (especially when changing positions suddenly), caution should be exercised when performing activities that require concentration such as driving or operating machinery during periods of time. use medicine. To use the drug safely, the patient needs to use the drug exactly as prescribed by the doctor. When there are abnormal signs, it is necessary to go to the medical examination and treatment facility for timely examination and medical intervention.
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