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Spasmaverine has the main active ingredient Alverine (in the form of alverine citrate) and other excipients with a sufficient amount of one tablet. This is a drug commonly used in pain related to gastrointestinal, urinary and genital smooth muscle spasms (dysmenorrhea, postpartum).1. What is Spasmaverine?
1.1. Pharmacodynamics of Spasmaverine
Spasmaverine, also known as Alverin, is a Papaverin antispasmodic. This drug has a direct effect on smooth muscle fibers (digestive, urinary, genitourinary) without acting on blood vessels, heart or bronchi.Due to the absence of an atropine-like effect, Spasmaverine can be used in the treatment of glaucoma or prostate enlargement.
1.2. Indications for Spasmaverine
Spasmaverine is indicated for the symptomatic treatment of pain caused by spasms of smooth muscles of the gastrointestinal tract, urinary tract and genitals (dysmenorrhea, postpartum pain).1.3. Pharmacokinetics of Spasmaverine
Spasmaverine is absorbed from the gastrointestinal tract after oral administration and is rapidly converted to active metabolites, peak serum concentrations 1 to 1.5 hours after oral administration. When further metabolized to inactive substances, they are excreted in the urine by active renal excretion.1.4. Spasmaverine drugs
Spasmaverine Drugs have two strengths:Spasmaverine 60mg Capsules; Spasmaverine 120mg capsules. 120mg capsules have the word "Forte" added right after the brand name. The usual therapeutic dose for adults and children over 12 years of age is 60 - 120mg. You can take it once, two or three times a day, depending on your doctor's prescription and the severity of the disease. Alverine is not suitable for children under 12 years of age.
2. What disease does Spasmaverine treat?
Symptomatic treatment of pain signs caused by gastrointestinal and biliary tract dysfunction. Treatment of signs of pain or spasm in the urogenital region (dysmenorrhea, labor pain, renal colic and urinary tract pain, threatened miscarriage, difficult delivery).3. Usage and dosage of Spasmaverine
3.1. How to use Spasmaverine?
Spasmaverine is taken orally.You take the capsule with water. You can take Spasmaverine before or after a meal. You should use the medicine as directed by your doctor and check the information on the label for the correct dosing instructions. In particular, do not use the drug at a lower or higher dose or for longer than the prescribed time.
3.2. Dosage of Spasmaverine
Therapeutic dose and use of Spasmaverine include:For adults (including the elderly): 1 or 2 tablets/time, use 1 to 3 times/day. For children 12 years and older, the dose is the same as for adults. The drug is not recommended for use in nursing women and children under 12 years of age. Spasmaverine medicine 60mg used for pregnant women does not cause birth defects or birth defects. However, you need to be very careful when using the drug during pregnancy. You should only use the drug when prescribed by a specialist after weighing the benefits and risks of using the drug for the mother and the fetus Note: The above treatment dose is for reference only. Refer to manufacturer's recommendations. The specific dose depends on the health status of each person and the progression of the disease. For a specific and appropriate therapeutic dose, you need to consult a specialist or medical professional.
3.3. In case of over/missing dose
In case of overdose: May cause hypotension and signs and symptoms of toxicity. Management of Spasmaverine overdose is similar to that of atropin poisoning and supportive measures to lower blood pressure. In case of an emergency, call 911 immediately or go to the nearest medical facility for timely and correct treatment. In case of missed dose: If you miss a dose of Spasmaverine, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Note that the drug should never be used with double the prescribed dose.
4. Undesirable effects of the drug Spasmaverine
You may experience nausea, headache, dizziness, itchy skin, red rash, allergic reactions (including anaphylaxis). Therefore, it is necessary to inform the doctor about the unwanted effects encountered while using Spasmaverine. Although the toxicity of Spasmaverine is relatively low after oral administration, in fact there have been cases of gastrointestinal side effects (nausea, diarrhea, constipation, loss of appetite), hepatitis, god, dozing off,... be notified. For people with glaucoma, the drug should be used with caution. Do not use Spasmaverine for a long time because it can lead to dependence on the drug. The drug should be discontinued when symptoms of gastrointestinal disturbances, jaundice or changes in liver function test results occur.5. Drug interactions
Spasmaverine may change how other medicines you are taking work or increase the effects of unwanted effects. To avoid drug interactions, it is best to make a list of all the medicines you are taking and show them to your treating doctor or pharmacist. To ensure safety when using Spasmaverine, do not arbitrarily use the drug, stop or change the dose of the drug without the permission of your doctor. Food, alcohol, or tobacco can cause interactions with certain medications. Talk to your doctor about taking your medication with food, alcohol, and tobacco.6. Some notes when treating Spasmaverine
Before using Spasmaverine, you need to carefully read the instructions for use and refer to the information below.Spasmaverine should not be used in people who:
Paralytic ileus or intestinal obstruction; Loss of colon tone; Women who are pregnant or breastfeeding; Hypersensitivity or hypersensitivity to any of the ingredients of the drug. The following cases should be used with caution when using Spasmaverine and need medical advice including:
Fever; Passing out blood ; Severe constipation; Middle age from 40 years old and above; Difficult or painful urination; There are signs of pregnancy; Loss of appetite or weight loss; Recently went abroad; Abnormal vaginal bleeding; Feeling very tired or nauseous; Looking pale or feeling very tired. Consult your doctor if new symptoms appear or become worse, or if signs and symptoms do not improve after 2 weeks of treatment.
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