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Stresam is a preparation containing the agent that relieves stress and anxiety, etifoxine. Stresam is used to reduce anxiety, fear, agitation, nervous tension, depression (including cardiovascular diseases and other underlying conditions).
1. What is Stresam 50mg?
Antidepressant Stresam belongs to the group of psychotropic drugs used to treat depression, epilepsy, and parkinsonism. The dosage form of the drug is in the form of hard capsules. The main ingredient of the drug is Etifoxine hydrochloride and other excipients.
2. What are the effects of Stresam?
2.1. Pharmacodynamics of Stresam antidepressants Stresam 50mg has the main active ingredient Etifoxine hydrochloride. This is an active ingredient in the benzoxazine group with selective effects on the Cl- channel of the GABA system, which acts on the autonomic nervous system through a dual mechanism. Therefore, the drug does not cause unwanted effects such as affecting the important functions of the body, but has a regulating effect on the autonomic nervous system. Etifoxine is effective against chronic physical and mental anxiety-inducing stressors: in clinical pharmacology, it has been shown to reduce various responses to stress (such as: emotional temperament, increased blood pressure, increased plasma free fatty acids, increased secretion of cortisol, etc.). Etifoxine is characterized by the maintenance and improvement of adaptability, without affecting alertness, memory, and muscle tone like benzodiazepines. Etifoxine does not cause dependence. Clinically, it is possible to prolong treatment with the antidepressant Stresam for 6-12 months without any withdrawal symptoms after discontinuation of the drug. 2.2. Pharmacokinetics of the depressant Stresam Etifoxine is absorbed mainly through the gastrointestinal mucosa. The active substance reaches its maximum concentration in the blood about 2 hours and 30 minutes after taking the drug. The mean half-life is about 6 hours. Therefore, it is necessary to treat with stress medication 3 times / day. In the liver, etifoxine is partially metabolised. An active metabolite, diethyl-etifoxine, is rapidly occurring and binds to the same receptors as etifoxine. The half-life of this metabolite averages about 24 hours. This explains why the optimal effect of Etifoxine is achieved within a few days. Etifoxine is excreted in the urine as metabolites.
3. What diseases does Stress treat?
Stress medication is used to treat the following conditions:
The psycho-physical signs of anxiety such as nervousness, loss of concentration, memory loss; Sleep disorders ; Autonomic disorders, especially cardiovascular manifestations such as (palpitations, palpitations, palpitations, hypertension...), digestive (irritable colon syndrome, stomach ulcers) gastric ulcer, duodenal ulcer...).
4. Undesirable effects of the drug Stresam
During the treatment with antidepressants Stressam may experience the following undesirable side effects:
Appears rapid transient drowsiness during the day. Very rare cases of erythema nodosum, urticaria Quincke edema. Some cases of hepatobiliary side effects, bleeding in women used in combination with oral contraceptives; Vasculitis in Stevens Johnson syndrome. The above are not all undesirable effects that may be encountered when using the stress medication, so consult your doctor if you experience any unusual signs for your health. .
5. Usage and dosage of the drug Stresam
5.1. How to use Stresam Tablets are hard capsules, you need to take them whole with a little boiled water to cool, do not peel the capsule in half.
5.2. Dosage of Stresam Depending on the medical condition and age of each person, the treating doctor will prescribe a separate dose. Dosage below is a reference dose:
Used to treat children over 15 years old and adults can take a dose of 3 tablets a day divided into 3 times or a dose of 4 tablets a day divided into 2 times. Treatment takes a few days to a few weeks, depending on the individual's medical condition. If the drug is used in children under 15 years of age, there are no clinical studies on the safety of Stresam antidepressants. 5.3. In case of overdose/forgotten dose of Stresam Stress medication does not have a specific antidote, so when an overdose occurs, you are likely to fall into a deep sleep, so you need to go to the nearest medical facility immediately. to promptly treat symptoms, minimize dangerous complications.
When you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next full dose. Do not increase the dose without consulting your doctor. treat.
6. Stresam drug interactions
You should not combine Stresam antidepressants in the following cases:
Alcoholic drinks such as beer, wine because of the risk of increasing the sedative effect of the drug. Therefore, the use of alcohol-containing beverages and drugs should be avoided while using the stress medication. Central nervous system depressants such as morphine derivatives, benzodiazepines, H1 antihistamines, tricyclic antidepressants, should be used with caution in combination with Stresam depressants. The reason is that can increase the effect on the nerve when used together. At the same time, you need to be careful when using it with drugs to treat central hypertension.
7. One point to keep in mind when using stress medication
Discontinue Stresam depressants in the event of skin reactions or allergic conditions or the onset of serious liver disorders. The drug formula contains the excipient is lactose. Therefore, the drug is not recommended for people with lactose intolerance. Caution should be exercised when co-administering with drugs that cause CNS depressants. The use of Stresam antidepressants is not recommended in pregnant and lactating women due to unknown safety and efficacy in this population. The drug can cause drowsiness because it can affect the central nervous system, so it should be used with caution in a group of subjects that require a high level of concentration when working, such as driving or using machines. Therefore, you need to pay attention to consult your treating doctor to ensure safety in work as well as drug use.
8. How to store antidepressant Stressam
Stresam antidepressants need to be stored at a temperature below 30°C, avoid direct exposure to light, do not keep the medicine in the refrigerator compartment. Keep out of reach of children and household pets. Absolutely do not use the medicine after the expiry date indicated on the packaging.
Stresam is a medication that treats symptoms of stress, anxiety, and depression. To ensure effective use and avoid unwanted side effects, you should carefully read the instructions or strictly follow the instructions of the treating doctor.
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