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Sulpirid is a drug acting on the nervous system with the main active ingredient being Sulpiride of the benzamide group used in the treatment of depression, positive symptoms of schizophrenia. What is Sulpiride?
1. Effects of Sulpiride 50mg
What is Sulpiride 50mg? Sulpirid is a drug of the benzamide group with effects on the nervous system, the main active ingredient is Sulpirid with a content of 50mg, in addition to other excipients such as tapioca starch, lactose monohydrate, povidone K30, MCC 102, talc, aerosil , sodium starch glycolate, magnesium stearate. Sulpiride has antipsychotic and antidepressant effects through selective mechanism of dopamine D2 receptors in the forebrain. Sulpiride 50mg is used as a low-dose antidepressant and is effective for high-dose schizophrenia positive symptoms. What disease does Sulpirid 50mg treat? In addition, Sulpirid 50mg is indicated for the short-term treatment of anxiety symptoms in adults in the event of failure of other treatments including:Severe behavioral disorders in children such as anxiety, self-mutilation or mutilation Autism syndrome Acute and chronic schizophrenia Tourette syndrome In addition, certain other drug effects not listed on the approved drug label, but In some cases, the doctor may prescribe the use of Sulpiride. Therefore, before taking the medicine, the patient should consult the doctor.
2. How to use Sulpiride
Sulpirid is made in the form of round tablets and is white or ivory white, with a smooth surface produced in blisters. Dosage will be based on the condition and age of the patient.
Short-term treatment of anxiety symptoms in adults: Treatment with a dose of 50-150mg/day for up to 4 weeks, or treatment of severe behavioral disorders. Use in children over 6 years old with a daily dose of 5-10mg/kg.
Treatment of acute and chronic schizophrenia: only use the drug in children over 14 years old and adults with the following dosage:
Positive cases with symptoms of schizophrenia from 200-400mg/time and take 2 times / day, the maximum dose is 1.2 grams / day. In case of negative symptoms of schizophrenia, 200-400mg/time, taken twice a day and the maximum dose is 800mg/day. Negative and positive symptoms combined from 400-600mg/time taken 2 times a day Treatment of tourette syndrome: for children from 12-18 years old, take a dose of 100-400mg/time, take 2 times a day. For children from 6-12 years old, take 50-400mg/time, take 2 times a day. Children under 6 years old should not use Sulpiride tablets.
Treatment in patients with renal failure:
Creatinine clearance from 30-60ml/min, the treatment dose is 2/3 of the normal dose or the dose interval is 1.5 times higher than normal. For creatinine clearance between 10-30ml/min, treat with 1/2 dose of normal dose or dose interval from 2 times normal. If creatinine clearance is <10 ml/min, then the dose should be 1/3 of the normal dose or the dose interval should be 3 times normal. Patients can take the drug with or without food, before or after eating. However, to reduce stomach irritation you can take it with food and need to take the tablet whole with a full glass of water, do not chew or break the tablet.
To use the drug safely, take Sulpiride exactly as directed by your doctor, do not use more than the recommended dose, smaller or longer than prescribed. Use Sulpiride regularly to get the most benefit from it and you can stop taking it if any new symptoms appear or the condition does not improve after 7 days. Patients absolutely do not abuse the drug for too long for a long time. This does not make the patient's condition better, but also increases the risk of unwanted effects.
3. Undesirable effects when using Sulpirid 50mg
Sulpirid medicine can cause some unwanted and common side effects that can be mentioned as:
Tremors Stiffness Movement disorders Over-stimulation Extrapyramidal syndrome: crooked neck, gyrus, restless breathing wheezing Shortness of breath Slow heart rate or arrhythmias Chest pain Dizziness Palpitations Cyanosis Lower blood pressure Increased lactation in women Unusual weight gain Increased salivation Rash Drowsiness Before prescribing medication, the doctor always consider the benefits and effectiveness of the drug Sulpiride. However, during the use of Sulpiride can still occur unwanted effects. Therefore, when unusual symptoms are present, especially when a severe allergic reaction occurs with accompanying signs such as severe dizziness, difficulty breathing, rash, anxiety, cognitive impairment , respiratory failure and coma, the patient should immediately notify the doctor or nurse for immediate medical intervention.
4. Some notes when using Sulpirid 50mg
Some notes when using Sulpirid include:
History of allergy to Sulpirid hypersensitivity reaction to any other allergy. Sulpiride may contain inactive ingredients and could cause an allergic reaction or other serious problems. Report any medications you are taking including prescription and nonprescription drugs, herbs and supplements, foods, dyes or preservatives. Sulpiride is contraindicated in patients with caution to use in patients over 65 years of age, especially those who have had a stroke, dementia, family history or personal history of blood clots or problems kidney problems, heart disease or a family history of cardiovascular disease or current mania or epilepsy, high blood pressure Blood glucose monitoring for patients with diabetes or at risk for diabetes when initiating sulpiride treatment. Caution should be exercised in patients with rare hereditary problems of galactose intolerance, glucose-galactose malabsorption, lactase deficiency. When using Sulpiride, it is necessary to be careful with alcohol users because the drug has the effect of increasing drowsiness and affecting driving and operating machinery. If you forget to take a dose of Sulpiride, take it as soon as possible. However, if it is close to the time of your next dose, skip the missed dose and continue taking or injecting the medicine as scheduled. Do not use more drug than the treatment regimen. Sulpiride overdose or ingestion can cause serious symptoms such as dystonia of the tongue and jaw, decreased consciousness, muscle spasms, tremors, difficulty moving or uncontrolled movements. , increased salivation, lightheadedness, dizziness, fainting,...
5. Drug interactions
Drug interactions can reduce the effect of Sulpiride, or increase the effect of unwanted effects. Tell your doctor about all other medicines you are taking including over-the-counter medicines, vitamins, prescription drugs, and herbal products. Do not start, stop or change the dose of any medicine without your doctor's consent.
Some drugs that can interact with Sulpiride include:
Evodopa Non-Parkinsonian dopamine agonists: carbegolin, quinagoline Some drugs for sleep or anxiety relief: morphine derivatives, tranquilizers neuroleptics, benzodiazepines, barbiturates, anxiolytics other than benzodiazepines such as meprobamate, hypnotics, sedative antidepressants. Medicines for high blood pressure such as clonidine, digitalis, diltiazem, verapamil. Anti-allergic drugs (antihistamines can cause drowsiness) such as chloramine, ketotifen, promethazine. The drug can cause torsades de pointes. Sucralfate is used in the treatment of lithium stomach pain. Beta-blockers in heart failure: bisoprolol, carvedilol, metoprolol, nebivolol. Drugs that lower blood potassium: Diuretics, drugs for constipation can reduce blood potassium levels Some antibiotics such as erythromycin, amphotericin B. Steroids used for anti-inflammatory such as prednisolone, dexamethasone, betamethasone.
6. How to store Sulpirid 50mg
Store Sulpirid with film-coated tablets at room temperature below 30 degrees Celsius, protected from light and away from moisture. Do not store Sulpirid in a humid place or in the freezer and keep away from heat and open flames. Different medicines will have different storage methods, so read the Sulpiride storage instructions carefully on the package, or ask your pharmacist. Keep Sulpiride out of the reach of children and family pets. When the medicine has expired or is damaged and cannot be used anymore, dispose of it and dispose of it properly. Do not arbitrarily dispose of Sulpiride into the environment such as a water pipe or toilet unless requested. Consult with your waste disposal company or pharmacist on how to safely dispose of Sulpiride to help protect the environment.
In summary, Sulpiride is used as a low-dose antidepressant and is effective for the positive symptoms of high-dose schizophrenia, autistic syndrome, acute and chronic schizophrenia, syndrome tourette syndrome,... However, Sulpiride can cause some unwanted effects and drug interactions, so tell your doctor what medications you're taking to reduce the chance of unwanted effects. desired and at the same time increase the effectiveness of the treatment process.
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