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Secnidazol 500mg is one of the drugs used to treat a number of gastrointestinal diseases. To better understand what is Glotadol 650? What are the uses of Secnidazole? What points do you need to pay attention to, and pay attention to when using? The following article will help you better understand the drug Secnidazole 500mg.
1. What is Secnidazol 500mg?
Secnidazole is a derivative of 5-nitroimidazole. The drug has parasitic activity: Entamoeba histolytica, Giardia intestinalis, Trichomonas vaginalis and anaerobic bacteria activity.
Drug form and strength
Film-coated tablets: 500 mg;
Ingredients: Secnidazole
2. What are the uses of Secnidazol 500mg?
Secnidazole is used to treat a certain type of vaginal infection (bacterial vaginosis). Secnidazol is an antibiotic that works by stopping the growth of bacteria. Secnidazol is indicated for the treatment of the following diseases:
Liver amoeba; Acute intestinal amoeba; Intestinal amoebiasis with no symptoms; Vaginitis due to bacterial infection; Vaginitis caused by bacteria Trichomonas; Giardiasis . This antibiotic only treats bacterial infections, not viral infections (such as the common cold, flu). Arbitrarily using any antibiotic when it is not needed can make the body resistant to future infections.
3. How to use Secnidazol 500mg effectively
Adults
Urethritis and vaginitis caused by Trichomonas vaginalis and bacterial vaginosis: Dose 2 g, take a single dose at the beginning of a meal. Simultaneous treatment of sexually active persons with the same dose as above. Symptomatic acute amoebic dysentery (histolytica form): 2 g dose, taken as a single dose at the beginning of a meal. Amoebic dysentery (amoebic dysentery) (minuta and cystic forms): Dose of 2g per day orally at the beginning of meals, taken for 3 days Liver amoeba: Dose of 1.5 g/day and taken as 1 time or divided orally several times at the beginning of meals, for 5 days. In the festering stage of hepatic amoebiasis, it is necessary to carry out treatment with Secnidazole in combination with purulent drainage Children (if any)
Intestinal amoebic dysentery:
Acute symptomatic amoebic dysentery (histolytica form) ): Single dose is about 30 mg/kg/day orally taken as 1 time, only for 1 day
Liver amoeba: Dose of 30mg/kg/day is taken as 1 time or divided into several times at the beginning of meals , in 5 days. In the festering stage of liver amebiasis, it is necessary to perform treatment with Secnidazole in combination with purulent drainage
Giardia disease: The dose is 30mg/kg/day and taken as a single dose, only used for 1 day. .
How to use
For nuggets, sprinkle the whole medicine in 1 pack on liquid food, easy to swallow such as yogurt, soft cakes, apple sauce and mix well. Note that do not drink with water and other liquids. Eat the whole mixture within 30 minutes and avoid chewing or crushing the nuggets. After eating, you can drink about 1 glass of water to make it easier to swallow.
What are the side effects of Secnidazole?
Common
Gastrointestinal disorders with symptoms such as: nausea, epigastric pain, taste changes (metallic taste in the mouth), glossitis, stomatitis.
Urticaria. Vaginal Candida infection with symptoms such as vaginal itching, redness, unusual yellow or milky discharge.
Uncommon
Moderate leukopenia, reversible upon discontinuation of the drug.
Rare
Hypersensitivity reactions: Fever, erythema, urticaria, angioedema. Dizziness, loss of coordination, ataxia, paresthesia, polyneuropathy - motor, seizures. Agranulocytosis, dark urine. Remember that your doctor has prescribed this medicine because he or she has judged that the benefit to you is greater than the risk of side effects. Many people who use this drug have no serious side effects. Occasionally, you may experience vaginal discomfort/itching/discharge or worsening. These symptoms may be due to a new vaginal infection (such as a yeast/fungal infection). Contact your doctor if you notice a change in vaginal discharge or new vaginal symptoms. Very serious allergic reactions to this medicine are very rare. However, get emergency medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, shortness of breath. Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about side effects, please consult your doctor or pharmacist.
4. Adverse interactions of Secnidazol 500mg
Should not be combined with
Disulfiram : Causing paranoia, confusion. Alcohol: Causes hot reactions, flushing, vomiting, heart palpitations. Caution should be exercised when co-administering with oral anticoagulants due to increased effects of oral anticoagulants and increased risk of bleeding due to decreased hepatic catabolism. It is necessary to regularly check prothrombin and monitor the INR (International normalized ratio). Dosage adjustment of oral anticoagulants during treatment with Secnidazole and for 8 days after discontinuation of Secnidazole.
5. Overdose, missed dose and how to handle it
Overdose and toxicity:
When taking high doses of Secnidazole (up to 15g) will lead to drug poisoning. Symptoms will include nausea, vomiting, and ataxia. Neurotoxic effects including convulsions and peripheral neuritis within 5 to 7 days after overdose have been reported.
Treatment:
There is no specific antidote. Symptomatic and supportive treatment. Drugs can also be effectively removed from the body by hemodialysis.
Missed dose and treatment:
When you forget to take a dose, take it when you remember. However, when it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Do not take twice the prescribed dose.
6. Precautions when using Secnidazole
Before using Secnidazole, tell your doctor or pharmacist if you are allergic to it; other antibiotics (such as tinidazole) or if you have any other allergies. This product may also contain inactive ingredients, leading to allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication tell your doctor or pharmacist your medical history. Secnidazole may also make live bacterial vaccines (such as typhoid vaccine) not work as well. Do not have any immunizations/vaccinations while using this medicine unless your doctor agrees. Before surgery, tell your doctor or dentist about all the products you use (including prescription drugs, over-the-counter medicines, and herbal products). During pregnancy, this medicine should also be used only when clearly needed. Discuss with your doctor the risks and benefits. It is not known whether this medicine passes into breast milk. Because the medicine can harm an unborn baby, you should not breast-feed while using this medicine and for 4 days after you stop it. Consult your doctor immediately before breast-feeding. Storage
Store in a dry place and at a temperature not exceeding 25 degrees Celsius and protect from light.
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