Rebamipide is a gastric medication, used for acid suppression, reflux prevention, and gastric ulcer treatment. It is formulated in the form of 100mg film-coated tablets.
1. Indications of Rebamipide 100mg
Rebamipide 100mg contains Rebamipide as the active ingredient, a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide helps prevent damage to the gastric mucosa in ulcerative tissues, supports increased blood flow to ischemic mucosa, accelerates the healing process of the mucosa, and protects the gastric mucosa from acute damage caused by various harmful and ulcerogenic factors.
Due to these benefits, Rebamipide is commonly prescribed for the following conditions:
• Gastric ulcers;
• Treatment of gastric mucosal lesions (bleeding, erosion, redness, edema) in conditions such as acute gastritis and exacerbations of chronic gastritis;
• Oral mucositis.
2. Instructions for Use of Rebamipide 100mg
Rebamipide should be used according to the instructions and prescription of a doctor. The following are suggested dosages for adults and are for reference only:
• Treatment of gastric ulcers: Take Rebamipide 100mg three times a day.
• Treatment of gastric mucosal lesions due to acute gastritis and exacerbations of chronic gastritis: Take Rebamipide 100mg three times a day.
• Treatment of oral mucositis: Take Rebamipide 100mg three times a day.
Timing of the medication: Take the medication in the morning, evening, and before bedtime. It can be taken with or without food, as food does not affect the drug's bioavailability.
*Note: The safety of Rebamipide in children has not yet been established, so it should not be used to treat this age group without medical supervision.
3. Side Effects of Rebamipide
There have been few reports of common side effects associated with Rebamipide.
However, in rare cases, the drug may cause some side effects, including:
• Leukopenia;
• Liver dysfunction;
• Eczema, rash, itching;
• Constipation;
• Diarrhea;
• Abdominal bloating;
• Heartburn;
• Nausea;
• Taste disturbances;
• Menstrual disorders;
• Possible swelling or enlargement of the breasts (gynecomastia in men);
• Shock and anaphylactic reactions.
4. Precautions When Using Rebamipide
Before using Rebamipide for treatment, users should pay special attention to the following precautions:
• For elderly patients: Close monitoring is necessary to reduce the risk of gastrointestinal disturbances, as this group is more sensitive compared to younger individuals;
• The safety of Rebamipide in neonates, low-birth-weight infants, and children has not been established, so the drug should not be used in these groups;
• Rebamipide may pose risks to pregnant women or those planning to become pregnant. These patients should only use the medication if the doctor believes the expected benefits outweigh any potential risks;
• If an allergic reaction occurs during treatment, the medication should be discontinued immediately;
• If there is a significant increase in liver aspartate transaminase (AST) levels, or if fever and rash develop, the medication should be stopped, and appropriate treatment measures should be taken.
Rebamipide 100mg should not be used by the following individuals:
• Patients with gastric cancer should have the cancer removed before starting treatment with this medication;
• Individuals who are hypersensitive to the active ingredient Rebamipide or any component of the medication;
• Breastfeeding women should not use this medication. If treatment is necessary, breastfeeding should be discontinued before starting the medication;
• Rebamipide may cause dizziness, tremors, drowsiness, etc., so it is advised not to use it for individuals operating machinery, driving, or needing to focus intensely.
Due to its effective anti-reflux and anti-ulcer properties, Rebamipide 100mg is currently being used to treat many patients with gastric mucosal and oral mucosal lesions. The above information provides details about the drug's uses and dosage, which patients can refer to for the best treatment approach.
To ensure effective treatment and avoid unwanted side effects, patients should follow the guidance of their doctor or qualified pharmacist.
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