What disease does Itopride treat?

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Itopride medicine 50mg is indicated for the treatment of esophageal reflux conditions, indigestion, diseases and symptoms related to the intestinal tract and stomach. Let's learn about itopride drug in the article below.

1. What is Itopride?

Itopride 50mg is a prescription drug, used as prescribed by a doctor. The main ingredient in Itopride 50mg is Itopride HCl with a concentration of 50mg. This ingredient is a prokinetic benzamide derivative that has good effects on the digestive system and intestinal tract. Itopride HCl is an antagonist that acts on D2 receptor antagonists (Dopamine). As a result, it inhibits Acetylcholine degradation and Acetylcholine release.
Itopride HCl has the effect of improving peristalsis in the intestinal tract and digestive system, accelerating the emptying time of the stomach and esophagus. This active ingredient is applied in many pharmaceutical products to help improve symptoms such as upper abdominal pain, chronic gastritis, ... and other gastrointestinal diseases.

2. Indications of Itopride 50mg

Itopride is indicated in the following cases:
Treatment of gastrointestinal symptoms caused by chronic gastritis such as abdominal distension, epigastric pain, loss of appetite, heartburn, nausea and vomiting. The drug is for adults only.

3. How to take Itopride 50mg

Usage: Itopride is recommended on an empty stomach, on an empty stomach, before meals. Patients should take the drug about 1 hour before the main meal to ensure its effectiveness. When taking, should swallow the same amount of water, do not break, bite or chew the medicine because it can affect the structure and therapeutic effects of the drug. Use the medicine exactly for the prescribed time, even if the symptoms of the disease improve, do not stop using the medicine. You should consult your doctor before stopping taking the medicine. Dosage: Adults: The usual oral dose for adults is 150 mg Itopride Hydrochloride (3 tablets) per day, divided into 3 times, 1 tablet each time. This dose may be reduced depending on the age and medical condition of the patient. The maximum duration of use is 8 weeks. Children: The safety and effectiveness of Itopride in children have not been established. Patients with hepatic or renal impairment: Itopride is metabolised in the liver. Itopride and its metabolites are eliminated primarily by the kidneys. Patients with reduced liver or kidney function should be carefully monitored and monitored; In the event of adverse reactions, appropriate measures such as dose reduction or discontinuation of treatment may be required. Elderly: Because of reduced physiological function in the elderly, adverse reactions are more likely to occur. Therefore, elderly patients receiving this drug should be carefully monitored, especially in patients with renal dysfunction, comorbidities, or concomitant use of other medicinal products. If any adverse reactions occur, appropriate management measures such as dose reduction or discontinuation should be used.

4. Contraindications of Itopride 50mg

Itopride should not be used in the following cases:
Contraindicated for use in children. Hypersensitivity to any of the ingredients of the drug. Contraindicated for use in patients with increased gastrointestinal motility such as patients with gastrointestinal bleeding, mechanical intestinal obstruction or perforation.

5. Side effects of Itopride

Itopride hydrochloride is a dopamine antagonist, so it can cause extrapyramidal symptoms (usually an acute dystonic reaction); occurs commonly in children and adolescents, and at daily doses above 500 micrograms/kg.
Vibration paralysis and tardive dyskinesia occasionally occur, often due to prolonged treatment in elderly patients, especially in elderly women.
Other side effects include restlessness, drowsiness, anxiety, and diarrhea. Hypotension, hypertension, dizziness, headache, and depression may occur and there have been isolated reports of blood disorders, hypersensitivity reactions (rash, bronchospasm), and psychotic syndrome malignancy. Some other side effects such as stimulation of blood prolactin secretion can cause lactation or related disorders. Transient increases in plasma aldosterone concentrations have also been reported.

6. Precautions when using itopride

Care should be taken when using because the drug increases the activity of acetylcholine. Long-term use is not recommended unless there is an improvement in gastrointestinal symptoms. Because the medicine contains lactose, patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine. Caution for pregnant women: The safety of Itopride Hydrochloride in pregnancy has not been established. Therefore, this drug should only be used in pregnant women or women who may become pregnant when the desired benefits of therapy outweigh the possible risks. Note to Lactation: It has been reported that Itopride Hydrochloride is excreted in milk in animal studies (rats). This medicine should not be used during breastfeeding. If it is necessary to take the drug, do not breast-feed during treatment Notes on driving and operating machines: Although no effects on the ability to drive and use machines have been observed, the risk of Reduced alertness cannot be ruled out because the drug can cause tremors, headaches, dizziness, and fatigue. Patients are advised to exercise caution when engaging in hazardous activities requiring alertness, such as working at height, operating machinery, or driving a vehicle. Itopride 50mg is indicated for the treatment of conditions such as reflux oesophagitis, dyspepsia, diseases and symptoms related to the intestinal tract and stomach. To ensure effective treatment, patients need to take medicine according to prescription or consult a doctor, pharmacist for advice.

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