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Gardenal 100mg is a psychotropic drug indicated in the case of patients with convulsions, epilepsy, tetanus seizures, Strychnin poisoning, sleep disorders. Follow the article to better understand the effects of Gardenal 100mg.
1. What is Gardenal 100mg?
Gardenal 100mg is produced by Pharmaceutical Factory 120 - VIETNAM
Dosage form:
Gradenal tablets are packaged in pill boxes. One bottle contains 100 tablets with the main ingredient is Phenobarbital corresponding to the content of 100mg / tablet and excipients just enough 1 tablet.
Ingredients Phenobarbital: This is a derivative of barbituric acid with sedative, sedating and anticonvulsant effects.
With the mechanism of action of phenobarbital, for the central nervous system and sedative, the drug has the effect of reducing anxiety and stress.
By inhibiting cortical over-discharge and increasing the threshold of neuronal response to stimulation, they have anticonvulsant effects, macro-epileptic seizures, and partial seizures.
For other organs, the drug has a palliative effect on activity at therapeutic doses and inhibits respiration, circulation, vasodilation, muscle relaxation and hypotension at high doses. The drug also has the effect of relaxing smooth muscle and reducing metabolism, excretion and body temperature.
2. Effect of medicine gardenal 100mg
Anticonvulsants: Indications for use of Gardenal 100mg drug in the treatment of major epileptic seizures, partial seizures and convulsions. It is also used in the prevention of febrile convulsions in children.
Due to the phenobarbital component that induces bilirubin-conjugated enzyme in the liver, helping to reduce free bilirubin, Gardenal 100mg is indicated for use in cases of neonatal jaundice, congenital unconjugated hyperbilirubinemia, and non-haemolytic anemia. and chronic cholestasis in the liver.
With the sedative effect causing sleep, Gardenal 100mg is also used in cases of anxiety, irritability and insomnia (however, if used for a long time, it leads to withdrawal syndrome).
3. Instructions for use, correct dosage
Gardenal 100mg tablets should be taken orally.
Dosage of the drug and the time of taking the drug may change for each age, acquired disease. Use as directed by your doctor.
Anticonvulsant treatment:
Adults: 2 - 3 mg/kg/day Children: 3 - 4 mg/kg/day Soothe seizures:
Take 0.05 to 0.12 g/day Treatment Insomnia:
Take 1 tablet a day, take it in the evening before going to bed. Do not use the drug for more than 2 weeks because long-term use can cause addiction and lead to withdrawal syndrome. Use drugs to prevent hyperbilirubinemia:
Adults are used at a dose of 30-60 mg and taken 3 times a day Infants use a dose of 5 - 10 mg/kg/day and are taken in the first few days of life. Children up to 12 years old, the dose is 1 - 4 mg/kg and 3 times a day.
4. Contraindications to using Gardenal 100mg
Allergy or hypersensitivity to phenobarbital and any other ingredients of the drug. Because the drug has the effect of inhibiting respiration, circulation, vasodilatation, muscle relaxation and lowering blood pressure at high doses, it is contraindicated in patients with severe respiratory failure, dyspnea or obstruction. Because the drug has a side effect of causing porphyria, it should not be used in patients with porphyria. It is necessary to inform the doctor about the medical condition that has been or is present in order to prescribe a reasonable alternative medicine.
5. Gardenal 100mg . side effects
The drug has a CNS depressant effect, so it can cause unwanted effects such as drowsiness, somnolence, dizziness, confusion, ataxia, coordination, so it should be used with caution. people who are doing jobs that require alertness.
Uncommon: Long-term use: Macrocytic anemia due to folic acid deficiency, arthralgia, osteomalacia, rickets in children, mental disorders, allergic rash.
6. Dealing with missed dose or overdose
Missed dose:
If you forget to take a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Do not take double the prescribed dose.
Overdose:
Overdose of Gardenal 100mg can lead to acute poisoning: respiratory failure, cardiovascular collapse and coma.
It is necessary to notify the doctor immediately of unwanted effects when taking the drug.
7. Other Notes
Treatment of patients with epilepsy, do not stop the drug suddenly because it can cause a status epilepticus. Do not drink alcohol and soft drinks with alcohol while taking the drug. In young children, it is necessary to use vitamin D2 to prevent rickets. For pregnant women: Phenobarbital components cross the placenta will increase the risk of birth defects by 2 to 3 times compared to normal. Children can develop withdrawal syndrome when the mother uses phenobarbital during the first 3 months of pregnancy. When the mother uses phenobarbital during labor, it is necessary to pay attention to monitor the baby's breathing and give first aid if the drug is poisoned. It is necessary to weigh the advantages and disadvantages of the drug to decide whether to use it or not. For women who are breast-feeding: Phenobarbital is excreted in breast milk and the elimination of the drug is slower in the baby than in the mother, so it may cause longer drug accumulation and sedative effects for the baby. , so it is necessary to monitor the drug concentration in the child's blood to avoid poisoning. Above are the uses and doses of Gardenal 100mg. Patients need to carefully read the instructions for use, consult a doctor / pharmacist before using to ensure safety and maximize the effectiveness of treatment.
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