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Fanlazyl belongs to the group of anti-parasitic, anti-infective and anti-viral drugs. The drug contains the active ingredient metronidazole. So what does Fanlazyl do? Let's find out information about the drug Fanlazyl through the article below.1. What is Fanlazyl?
Fanlazyl belongs to the group of anti-parasitic, anti-infective and anti-viral drugs. Indicated in the treatment of trichomoniasis of the urinary tract - genitals in men and women, prevention of infections caused by anaerobic bacteria. The drug is composed of the main active ingredient Metronidazol 250mg. Excipients include: Tapioca starch, talcum powder, povidone, magnesium stearate) with sufficient content.Fanlazyl medicine is in the form of tablets. Packing specification is box of 2 blisters, 10 blisters x 10 tablets.
2. What are the effects of Fanlazyl?
2.1. Pharmacodynamics of the drug ingredient Fanlazyl Fanlazyl drug has the main ingredient Metronidazol, which is a Nitro-5 imidazole derivative. Metronidazole has a broad spectrum of activity against protozoa such as amoeba, Giardia and anaerobic bacteria.
2.2. Pharmacokinetics Absorption: Metronidazole is rapidly and completely absorbed after oral administration, at least 80% after 1 hour. Bioavailability is 100% and is not affected by food. Distribution: About 10-20% of the drug is bound to plasma proteins. Metronidazole penetrates well into tissues and body fluids, into saliva, crosses the placental barrier and passes into breast milk. Elimination: Metronidazole is metabolized in the liver to hydroxyl and acid metabolites, partly eliminated in the urine as glucuronide. The plasma half-life is about 7 hours. Approximately 14% of a dose is excreted in the feces. Fanlazyl is indicated for use in the following cases:
Treatment of infections with Trichomonas vaginalis, Entamoeba histolytica, Dientamoeba fragilis in children, Giardia lambia and Dracunculus medinensis. Treatment of trichomoniasis of the urinary tract - genitals in both men and women. Treatment of intra-abdominal infections, gynecological infections, skin and skin structure infections, central nervous system infections, sepsis and endocarditis. Surgical treatment of anaerobic bacterial infections. Prophylactic treatment of infections caused by anaerobic bacteria in colorectal surgery and gynecological surgery. Treatment of acute ulcerative necrotizing gingivitis, other dental infections caused by anaerobic bacteria. Patients with active Crohn's disease in the colon and rectum. Peptic ulcer disease caused by H. pylori bacteria.
3. How to use Fanlazyl
3.1. How to use the drug Fanlazyl For the drug Fanlazyl, patients use it orally. Take the medicine during or after a meal with some water.
3.2. Dosage of Fanlazyl The recommended dose of Fanlazyl for each specific case is as follows:
Trichomoniasis: A single dose of 2g or used for 7 days 3 times a day, 250mg each time, simultaneous treatment for both man and woman. Amoeba: Dosage for adults is 750mg/time, used 3 times a day, treatment for 5-10 days. Amoebic liver abscess: Dosage for adults is 500-700mg/time, used 3 times a day, treatment for 5-10 days. For children: Dosage is 34-40mg/kg/24 hours, divided into 3 times, taken for 5-10 days. Giardia disease: The recommended dose for adults is 250mg/time, 3 times a day, for 5-7 days. Or take once with a dose of 2g/day for 3 days. Children take 15mg/kg/day, divided into 3 times, treat for 5-10 days. Disease caused by dragon worms Dracunculus: Adults and children 25mg/kg/day, taken for 10 days, the daily dose should not exceed 750mg for children (including children over 30kg). Treatment of anaerobic bacterial infections: Oral dose of 7.5mg (base)/kg up to a maximum of 1g, every 6 hours, treatment for 7 days or longer. Antibiotic-associated colitis: Oral dose of 500mg (base form) 3-4 times daily. Peptic ulcer disease caused by H. pylori: Oral dose of 500mg (base) 3 times per day, in combination with other drugs as directed by the treating physician. Prevention of anaerobic infections after surgery: Dosage 20-30mg/kg/day, divided into 3 times. 3.3. How to handle when forgetting, overdosing Missed dose: If you miss a dose, you can usually take it 1 to 2 hours later than prescribed. However, if it is almost time for your next dose, skip the missed dose and continue as directed. Never use a double dose at the same time. Follow it properly or consult your doctor before making a decision.
Overdose: If an overdose of Fanlazyl is suspected, the patient should stop using the drug. Immediately notify the nearest doctor or medical facility when there are abnormal symptoms. Read the instructions for use carefully and consult your doctor before use.
3.4. Fanlazyl is contraindicated in the following cases:
Cases where the patient is allergic, sensitive to Metronidazol or any of its ingredients. Contraindicated in patients with a history of hypersensitivity to other Nitro - imidazole derivatives. Contraindicated for women in the first 3 months of pregnancy and when breastfeeding. Epilepsy patients. Blood clotting disorder.
4. Notes when using the drug Fanlazyl
Note and caution when using Fanlazyl
Metronidazol has an inhibitory effect on alcohol dehydrogenase and other alcohol oxidizing enzymes. The drug has mild disulfiram-type reactions such as hot flushes, headache, nausea, abdominal cramps and sweating. Metronidazole can immobilize Treponema pallidum, producing a false-positive response to the Nelson test. High doses can cause blood organ disorders and active neurological diseases. For pregnant women: There have been studies reporting the risk of teratogenicity when taking Fanlazyl in the first 3 months of pregnancy. Therefore, it should not be used during early pregnancy. For lactating women: Metronidazole is excreted in breast milk fairly rapidly. Breastfeeding should be discontinued during treatment with metronidazole. Side effects when using the drug Fanlazyl
Side effects when using the drug Fanlazyl usually depend on the dose. Long-term use of high doses increases the risk of adverse effects. When using Fanlazyl, you may encounter unwanted side effects that are sorted by frequency below:
Common: Headache, nausea, vomiting, loss of appetite, dry mouth, metallic taste very uncomfortable, diarrhea, epigastric pain, abdominal pain, constipation. Rare: Leukopenia, seizures, peripheral polyneuropathy, skin blistering, skin rash, rash, dark urine. Other: Pancreatitis, peripheral sensory neuropathy, reversible upon discontinuation of therapy. Interactions, drug incompatibilities Fanlazyl:
Metronidazol increases the effect of oral anticoagulants (Warfarin). Therefore, it should be avoided at the same time. Metronidazole has disulfiram-like effects. Note that these two drugs should not be used concurrently to avoid neurotoxic effects such as psychosis, confusion. Using Metronidazole for patients with high blood lithium levels will cause toxicity. Increases the effect of Vecuronium as a depolarizing muscle relaxant. Concomitant use with Phenobarbital will increase the metabolism of Metronidazole so the drug is eliminated faster. Consider when using Fanlazyl with alcoholic or fermented beverages, tobacco, avoiding agents that can change the drug's composition. Store the drug Fanlazyl:
Store the medicine at a temperature below 30°C, avoid direct sunlight, avoid moisture, keep in a cool and dry place. Keep out of reach of CHILDREN. Above is all the necessary information that patients need to know when using Fanlazyl. This is a prescription drug, patients need to follow the doctor's instructions to ensure the effectiveness of the drug and avoid unwanted side effects.
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