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Savixin drug belongs to the group of anti-parasitic, anti-viral and anti-infective drugs, with the ingredient Cephalexin. What precautions should be taken when using Savixin? Learn more about Savixin through the article below.
1. What is Savixin?
Savixin drug belongs to the group of drugs used to treat parasites, anti-infectives, antivirals and antifungals. Indicated in the treatment of bacterial infections, urinary tract, respiratory, skin and soft tissue infections.
Savixin medicine is made in the form of capsules or powder for oral suspension. Packing is a box of 5 blisters, 10 blisters x 10 capsules or a box of 10 packs x 3g.
The main ingredient in the drug is the active ingredient Cephalexin and the excipients in sufficient quantity include: Diameter, avicel, aspartame, aerosil, orange powder, strawberry powder, purified water.
2. What does Savixin do?
Savixin drug has the ingredient Cephalexin, this is a 1st generation Cephalosporin antibiotic, has bactericidal effect by inhibiting bacterial cell wall synthesis. Cephalexin has a medium spectrum of activity, active against gram-negative (-) and gram-positive (+) bacteria, and is effective against penicillin-resistant penicillinase-producing strains of Staphylococcus aureus (or ampicillin). In addition, Cephalexin is also active against most ampicillin-resistant E. coli.
Indications for Savixin:
Savixin is indicated for the treatment of infections caused by the following bacteria:
Upper respiratory tract infections: Ear - nose - throat infections such as otitis media, sinusitis, tonsillitis and tonsillitis. sore throat. Lower respiratory tract infections such as pneumonia, acute and chronic bronchitis, bronchiectasis with superinfection Skin and soft tissue infections such as pyoderma and impetigo. Urinary tract infections: Acute and chronic pyelonephritis, prostatitis. Prophylaxis of recurrent urinary tract infections. Obstetric and gynecological infections.
3. How to use Savixin
3.1. How to use Savixin: Patients use Savixin orally.
3.2. Dosage of Savixin: The recommended dosage of Savixin for each subject is as follows:
Adults and children over 12 years old: The recommended dose is 500mg x 3 times per day. Children 5 to 12 years: The recommended dose is 250mg 3 times daily. Children 1 to 5 years: The recommended dose is 125mg 3 times daily. Children under 1 year: The recommended dose is 125mg twice daily. Dosage should be considered and considered for the following cases:
For adults with severe or deep localized infections, especially less susceptible bacteria, consider increasing the dose 1 - 1.5g/time, 3 up to 4 times a day. Young children: Dosage should be calculated based on body weight. The usual recommended dose is 35-60mg/kg/day. In severe or deep localized infections, the dose may be increased to 100 mg/kg/day. In the elderly, the possibility of renal failure should be considered. 3.3. How to handle when forgetting, overdosing Savixin medicine Missed dose: If you forget a dose of Savixin, take a supplement as soon as you remember. However, if it is too far from the time you should take it, skip the missed dose and take the next dose exactly as directed by the qualified pharmacist or doctor in charge. Never use twice the dose at the same time.
Overdosage: To date, Cephalexin has not been shown to have nephrotoxicity, however, as with predominantly renally excreted antibiotics, an unnecessary accumulation may occur when renal function is reduced to less than one half normal.
When used in excess, the most common symptoms are nausea, vomiting and diarrhea, but can cause neuromuscular hypersensitivity and seizures, especially in people with renal failure.
Treatment of overdose: When an overdose of Savixin is suspected, stop taking the drug. Immediately notify the treating doctor for timely treatment. Dialysis can help remove drugs from the blood, but is usually not needed. Give activated charcoal several times in place of or in addition to gastric lavage.
3.4. Savixin is contraindicated in the following cases:
Cases where the patient is hypersensitive to the active ingredient Cephalexin, has a history of allergy to Cephalosporin antibiotics or any of its ingredients. Savixin should not be used in patients with a history of penicillin-induced anaphylaxis or other severe IgE immune globulin-mediated reactions.
4. Note when using Savixin
4.1 Precautions for use of Savixin In patients taking Cephalexin may cause false positive in Coombs test, urine glucose test. Cephalexin is generally well tolerated even in penicillin-allergic patients, although a very small number of cross-reactions have occurred. For patients with impaired renal function: Cephalexin is eliminated mainly by the kidneys, so the dose should be adjusted appropriately for these patients. For pregnant women: There are no data showing signs of fetal toxicity and teratogenicity. However, the drug should only be used for pregnant women when absolutely necessary and with the permission of a doctor. Lactation: Although concentrations of the drug in breast milk are very low, consideration should be given to discontinuing breast-feeding while the mother is taking the drug. 4.2 Side effects when using Savixin: When using Savixin, unwanted side effects may be encountered that are classified by frequency as follows:
Common:
Gastrointestinal: Diarrhea, nausea , vomit. Uncommon:
Blood: Eosinophilia. Skin: Rash, urticaria, itching. Liver: Reversible increase in liver transaminases. Rare:
Body as a whole: Dizziness, anaphylactic reactions, fatigue. Blood: Decrease in neutrophils. Digestive: Pseudomembranous colitis, digestive disorders. Skin: Stevens - Johnson syndrome, erythema multiforme, Quincke's edema, toxic epidermal necrolysis. Liver: Hepatitis, cholestatic jaundice. Urogenital - genitourinary: Reversible interstitial nephritis, genital itching, vaginitis. 4.3 Interactions and drug incompatibilities Savixin: The combined use of Cephalexin and probenecid will prolong the elimination time of Cephalexin and increase the serum concentration by 50 - 100%. Taking high doses of Cephalosporins with other drugs (such as aminoglycosides, furosemide, ethacrynic acid and piretanide) may adversely affect renal function. Therefore, Cephalexin should be used at the recommended dose.
Consult a pharmacist, doctor about taking Savixin with food, alcoholic beverages and tobacco. Avoid antagonism or synergism with the drug.
Above is all necessary information when using Savixin. Savixin is a prescription drug, so patients should not take it on their own and stop taking it without the permission of the treating doctor.
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