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Celestene is a steroid pain reliever medication. This is a very powerful drug compared to other drugs in the same class. The use of drugs can cause a lot of side effects if used incorrectly and abused. For you to know more about the drug, please refer to the use, use and notes when using the drug through the article below.1. What are the uses of Celestene?
Celestene medicine has the main active ingredient Betamethasone with a concentration of 4mg/ml, prepared in the form of a syringe. Betamethasone is a corticosteroid (adrenal hormone). Betamethasone has potent anti-inflammatory, anti-arthritic, and anti-allergic effects and is used in the treatment of corticosteroid-responsive disorders. It is a glucocorticoid, having high glucocorticoid activity and low mineralocorticoid activity.
Celestene 4mg is indicated in the following cases: Used in endocrine, musculoskeletal, collagen disorders, skin diseases, allergies, eyes, respiratory, blood, cancer and other diseases. other diseases that respond to corticosteroid therapy.
Hormonal disorders: primary or secondary adrenocortical insufficiency (use in combination with mineralocorticoids, if possible); congenital adrenal hyperplasia; Non-follicular thyroiditis and cancer-associated hypercalcemia. Musculoskeletal or skeletal disorders: used as a short-term adjunct in psoriatic rheumatism; rheumatoid arthritis ; ankylosing spondylitis ; acute and subacute bursitis; nonspecific acute synovitis; Gout; acute rheumatic fever and synovitis. Colloid disease: Used in the proliferative phase or in the maintenance treatment of some cases of systemic lupus erythematosus, acute rheumatic myocarditis, systemic scleroderma, and dermatomyositis. Skin diseases: Pemphigus disease; severe erythema multiforme (Stevens-Johnson syndrome); exfoliative dermatitis; mycosis fungoides; chronic dermatitis and urticaria. Allergic cases: The drug is used in cases of severe allergies or treatment failure after conventional treatments, such as seasonal or persistent allergic rhinitis, nasal polyps, bronchial asthma, contact dermatitis. contact, atopic dermatitis, drug and serum reactions. Eyes: acute and chronic inflammatory and allergic conjunctivitis, allergic conjunctivitis, keratitis, allergic corneal ulceration, iritis, ciliary iritis, choroiditis, retinitis, anterior fasciitis, inflammation Anterior choroidal vasculitis spreads posteriorly, optic neuritis, central retinitis, posterior neuritis. Respiratory: in symptomatic sarcoidosis; Loeffler syndrome not controlled by other methods; in combination with therapies in the treatment of acute and disseminated pulmonary tuberculosis; pneumothorax; pulmonary fibrosis, pneumonia... Blood: Idiopathic and secondary thrombocytopenia in adults; autoimmune hemolytic anemia; erythrocytopenia and anemia due to genetic hypoplasia; reaction to the parenteral route. Cancer : Used to temporarily treat blood cancer and lymphoma in adults, acute blood cancer in children. Edema due to several causes: Drugs with diuretic effect or to reduce proteinuria do not cause uremia in primary nephrotic syndrome or due to lupus erythematosus. Other indications: Ulcerative colitis; Bell's palsy (7 peripheral nerve palsy due to cold). In general, the use and indications of the drug are very broad. But you should choose to use it from the mouth and then inject or use it when the disease is severe and needs a quick response.
2. Contraindications of Celestene 4mg
The drug should not be used in the following cases:
People who have a sensitive reaction to Betamethasone or other corticosteroids or to any of the components of Celestene 4mg Do not use Betamethasone for mentally ill people, suffering from gastric and duodenal ulcers colon. Do not use in bacterial infections and in systemic fungal infections. Use with caution in people with diabetes because it can cause hyperglycemia.
3. How to take and dose of Celestene
Dosage varies depending on the subject and each specific disease. You can refer to the dosage of the drug as follows:
For adults: The dose can be from 4 to 20mg of betamethasone (1 to 5ml) intravenously slowly 30s to a minute. This dose may be repeated three or four times in 24 hours, depending on the doctor's request and the patient's response. Systemic route in children: Infants up to 12 months of age may be given 1mg of betamethasone as needed. Children from 1 to 5 years old: Use celestene 2mg; 6 to 12 years old taking celestene 4mg (1ml). This dose may be repeated three to four times in 24 hours, depending on the patient's condition and response. This dosage should only be used for reference, depending on the specific disease, the doctor will prescribe the appropriate drug.
4. Side effects when taking Celestene
Adverse effects of Celestene, as with other corticosteroids, are usually related to dose and duration of treatment.
Water and electrolyte disorders: When taking the drug, it will cause salt and water retention, congestive heart failure, potassium loss, increased blood pressure, decreased potassium. On the musculoskeletal system: Causes muscle weakness, corticosteroid myopathy, muscle mass loss, exacerbation of myasthenia gravis, osteoporosis, vertebral depression, aseptic necrosis of the femoral head and necrosis aseptic humeral head, pathological long bone fracture, ligament rupture. Gastrointestinal: Complicated peptic ulcer with gastric perforation or hemorrhage, pancreatitis, abdominal distention, esophagitis. Skin diseases: slow wound healing, thin skin; there are petechiae and ecchymosis; facial erythema; increased sweating; allergic conditions such as atopic dermatitis, urticaria; neurovascular edema. Neurological: convulsions, causing increased intracranial pressure with papilledema (causing pseudotumor in the brain) after treatment; dizzy; headache. Endocrine: menstrual disorders; pseudo-Cushing's syndrome; secondary adrenal and pituitary loss of response, particularly during times of stress; reduces carbohydrate tolerance; increase the need for insulin or other hypoglycemic agents in the treatment of diabetes. Eyes: Risk of subcapsular cataracts, glaucoma, glaucoma, bulging eyes. This risk should be taken into account in children with prolonged use. Psychiatric: causing a feeling of euphoria, a feeling of lightheadedness; manifestations of severe psychological impairment; personality changes; insomnia . Other effects: Anaphylaxis or hypersensitivity reactions may occur although very rarely. Side effects may vary from person to person. You need to inform your doctor about any unwanted effects that you experience while taking the drug.
5. Notes when using Celestene
You should note the following when taking the drug:
The lowest possible dose must be started to control the disease being treated; If you want to stop taking the drug, you must reduce the dose and gradually reduce it. Use exactly as prescribed by your doctor, do not suddenly stop using it. When using systemic corticosteroid therapy, caution must be exercised in cases of congestive heart failure, recent myocardial infarction, hypertension, epilepsy, glaucoma, hypothyroidism, patients with liver failure, osteoporosis, CKD. Patients on corticosteroid therapy are more susceptible to infections due to reduced resistance. On the other hand, the symptoms of these infections may be masked until late in the disease. Use with caution in pregnant and lactating women. It is generally not recommended to use it, only when absolutely necessary. Certain vaccines should not be given during corticosteroid treatment. Other immunosuppressive therapies should not be used in corticosteroid therapy, especially at high doses because of the potential for neurologic disturbances and loss of antibody response. However, in patients being treated with corticosteroids as an alternative therapy such as Addison's disease, immunotherapy can still be used. Patients taking corticosteroid doses cause a decrease in the immune response to pathogens, so it is necessary to pay attention to avoid contact with infectious disease sources, if exposed to these environments, need to consult a doctor immediately. This is especially important in children. Psychiatric disturbances may also occur during corticosteroid therapy, which may aggravate psychological instability and predisposition to psychosis. Because the complications of glucocorticoid therapy depend on the dose and duration of treatment, it is important to use the drug correctly and always consider its use. Drug Interactions: May occur when used with other drugs. So be very careful when using with some other drugs. Preservation of the drug: Should be stored at a temperature of 2-30 degrees Celsius in sealed packaging. Protect from light and do not allow the medicine to freeze. Keep out of reach of children. Celestene is a powerful steroid anti-inflammatory drug that can cause a lot of side effects if you take it wrong, abuse it, and prolong it. Therefore, you should only use it exactly as directed by your doctor.
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