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Axumin drug containing the active ingredient Fluciclovine F18 is used in positron emission tomography (PET) and computed tomography (CT) scans to locate recurrences in patients who have been treated for prostate cancer. . Let's learn about the uses, dosage and notes when using Axumin through the article below.
1. Uses of Axumin
"What is Axumin medicine?". Accordingly, the drug Axumin prepared in the form of injection contains the active ingredient Fluciclovine F18 - a compound similar to a synthetic amino acid. Amino acids are structural components of proteins used by cells for growth and metabolism. In prostate cancer cells, the demand for amino acids is increased, leading to an increased uptake of Fluciclovine F18 in prostate cancer cells and low in normal cells. Based on this principle, Axumin is indicated in positron emission tomography (PET) and computed tomography (CT) scans to locate recurrences in patients who have been treated for prostate cancer. and is currently exhibiting increased prostate-specific antigenicity.
Active ingredient Fluciclovine F18 has the strong point of localizing small metastatic nodes. The drug's performance is significantly better than that of a traditional CT scan. Fluciclovine F18 assists clinicians in the selection of therapeutic management in patients with suspected recurrent disease. In some cases, detecting small metastatic lymph nodes can change the treatment plan including surgery or radiation therapy. Because of these uses, Axumin should only be used under the supervision of medical personnel.
2. Dosage of Axumin
The drug Axumin used to identify prostate cancer is administered by injection and performed by medical staff. The dose of the drug prescribed by the treating doctor depends on the patient's condition.
Patients need to avoid activities, heavy exercise at least 1 day before the PET scan. Do not eat or drink any food for at least 4 hours before taking Axumin.
3. Side effects of Axumin
Axumin can cause some of the following side effects:
Rarely: Shortness of breath, chest tightness, unusual tiredness or weakness; Frequency not known: Difficulty swallowing, cough, dizziness, heart palpitations, hives, itching or skin rash, swelling of eyes or eyelids, swelling of face, lips, tongue or throat. Undesirable effects may disappear after a period of drug treatment. In case of any unwanted effects, the patient should notify the treating doctor for timely treatment.
4. Note when using Axumin
Contraindicated to use Axumin in patients allergic to any ingredient of the drug.
Precautions for use: Axumin can cause serious allergic reactions, including anaphylaxis with symptoms of tachycardia, rapid breathing, change in facial color, swelling of the face, puffiness of the eyes and eyelids. eye. In this case, the patient should be taken to a medical facility as soon as possible.
It is not recommended to use Axumin in children because safety and effectiveness have not been determined.
Scientific studies show that the elderly do not affect or limit the effects of Fluciclovine F18. Therefore, no dose adjustment is required in these subjects.
Pregnant women, lactating women: It is not recommended to use Axumin in pregnant and lactating women.
5. Axumin drug interactions
Drug - drug and drug - food and drink interactions occur, increasing the risk of experiencing side effects, reducing the effects of treatment drugs. Therefore, patients need to inform their doctor of all medicines they are using before being treated with Axumin to ensure safety and effectiveness.
Axumin drug containing the active ingredient Fluciclovine F18 is used in positron emission tomography (PET) and computed tomography (CT) scans to locate recurrences in patients who have been treated for prostate cancer. .
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Reference source: drugs.com
