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Bicamed 150 is prepared in the form of film-coated tablets with the main ingredient in each tablet is 150mg of Bicalutamide. So what are the uses of Bicamed 150 and how to use it?
1. Uses of Bicamed 150mg
The main ingredient of Bicamed 150 is Bicalutamide, which is a non-steroidal anti-androgen, it has no other endocrine activity. Bicalutamide binds to androgen receptors but has no expression of gene activation, so it inhibits androgen stimulation. This inhibition induces regression of prostate tumors.
Clinically, discontinuation of Bicalutamide may cause an antiandrogen withdrawal syndrome in some patients. Bicalutamide has been studied in patients with localized prostate cancer (T1-T2, N0 or NX, M0) or locally advanced prostate cancer (T3-T4, for all N, M0). ; T1-T2, N+, M0) have not metastasized.
Bicalutamide is indicated as an immediate hormone therapy or as adjunctive therapy in prostatectomy or radiation therapy.
Bicamed 150mg is indicated in the following cases:
Treatment of advanced prostate cancer in combination with hypothalamic hormone analogues that stimulate the secretion of luteinizing hormone (LHRH) or surgery. testicle resection. Bicamed 150mg is contraindicated in the following cases:
Women. Children. Hypersensitivity to Bicalutamide or any of the ingredients of Bicamed 150mg. People who are taking terfenadine, astemizol or cisaprid.
2. Usage and dosage of Bicamed 150mg
Bicamed 150mg is used orally. Dosage of Bicamed 150mg should be according to the doctor's instructions, the reference dose is as follows:
Adult men including the elderly: Use 1 tablet/day/time. Bicamed 150 mg should be treated for at least 3 days before initiating LHRH analog therapy or bicamed 150 mg at the same time as performing orchiectomy. No dose adjustment of Bicamed 150mg is required for patients with renal impairment. No dose adjustment of Bicamed 150mg is required for patients with mild hepatic impairment. An increase in the accumulation of Bicamed 150 mg may occur in patients with moderate to severe hepatic impairment. There have been no cases of overdose of Bicamed 150mg in humans. There is no specific antidote for Bicamed 150mg, the treatment is symptomatic treatment. General supportive therapy should be indicated and vital signs are regularly monitored.
3. Side effects of Bicamed 150mg
Very common side effects of Bicamed 150mg include:
Rash; gynecomastia in men; Breast tightness; Attenuate. Common side effects of the drug Bicamed 150mg include:
Insomnia; Anorexic; Sexual impairment ; Depression; Dizzy; Drowsiness; Hot flashes; Stomachache; Constipation; Undigested; Flatulence ; Nausea; Hepatotoxicity; Jaundice; Transaminases are elevated; Hair loss; Hirsutism ; Dry skin; Itchy; Hematuria; Erectile dysfunction; Chest pain; Edema ; Weight gain. Rare side effects of Bicamed 150mg include:
Sensitization reactions; Angioedema; Urticaria; Interstitial lung disease. Rare side effects of Bicamed 150mg include:
Liver failure. In the process of using Bicamed 150mg, if you see any unusual symptoms, you need to immediately notify your doctor or go to a medical facility for timely medical support.
4. Interactions with other drugs
Contraindications to concurrent use of Bicamed 150mg with the following drugs:
Terfenadine; Astemizole; Cisapride. Be careful when using Bicamed 150mg at the same time with:
Ciclosporin; Calcium channel blockers ; Drugs that have the ability to inhibit oxidation such as cimetidine and Ketoconazole. In theory, these drugs could increase blood levels of Bicalutamide and possibly increase the side effects of this medicine; Coumarin Anticoagulants: In vitro studies have shown that Bicalutamide competes with oral Coumarin anticoagulants for plasma protein binding sites. Therefore, it is necessary to closely monitor the prothrombin time test index when starting Bicamed 150mg in patients taking coumarin anticoagulants. Bicamed 150mg is made in the form of film coated tablets with the main ingredient in each tablet is Bicalutamide 150mg. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Bicamed 150mg exactly as directed by your doctor.