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Bicalutamide fct 150mg is made in the form of film coated tablets with the main ingredient in each tablet is Bicalutamide 150mg. So what is Bicalutamide, what does this drug do and how is it used?
1. What is Bicalutamide?
What is Bicalutamide? The main ingredient of Bicalutamide fct 150mg is Bicalutamide, which is a non-steroidal agent that works to reduce male sex hormone levels in the treatment of prostate cancer.
Bicalutamide binds to receptor proteins located on the surface of cancer cells. This makes it impossible for testosterone to get into cancer cells. Bicalutamide fct 150mg has anti-androgens effect.
Bicalutamide fct 150mg is indicated in the following cases:
Use alone or for adjuvant purposes in radical prostate surgery or radiation therapy for patients with locally advanced prostate cancer , have a high risk of disease progression. Bicalutamide fct 150mg is contraindicated in the following cases:
People with hypersensitivity to bicalutamide or any of the ingredients of Bicalutamide fct 150mg. Concomitant use with terfenadine, astemizol or cisapride. Women. Children and teenagers. Precautions when using Bicalutamide fct 150mg:
Patients should start using Bicalutamide fct 150mg under the close supervision of a specialist. Bicalutamide is metabolized mainly in the liver. Collected data indicate that the drug is eliminated more slowly in patients with severe hepatic impairment, which may lead to increased accumulation of bicalutamide in the body. Therefore, caution should be exercised when Bicalutamide fct 150mg is used in patients with moderate to severe hepatic impairment. It is recommended to periodically check liver function, because changes in liver function may occur when Bicalutamide fct 150mg is used. Most of these changes occurred within the first 6 months of drug use. In patients with progressive disease with elevated PSA, the physician should consider discontinuing treatment with Bicalutamide fct 150mg. Patients with heart disease, using Bicalutamide fct 150mg, should regularly monitor heart function. Bicalutamide inhibits cytochrome P450 (CYP3A4), so caution should be taken when co-administered with drugs metabolised primarily through CYP3A4. Bicalutamide fct 150mg contains lactose monohydrate, so patients with hereditary disorders of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption should not use this medicine. Bicalutamide fct 150mg may cause reversible impairment of fertility in men. This should be considered before using the drug.
2. Dosage and how to use Bicalutamide fct 150mg
Bicalutamide fct 150mg is used orally, patients can take the drug with or without food.
The dose of Bicalutamide fct 150mg should be according to the prescription of a specialist, the recommended dose is as follows:
The usual dose is 1 tablet once a day. The drug should be used continuously for at least 2 years or until disease progression. Patients with impaired renal function do not require dose adjustment. Patients with mild hepatic impairment do not require dose adjustment. At present, there is no experience with overdosage of Bicalutamide fct 150 mg in humans. Accordingly, there is also no specific antidote for Bicalutamide fct 150mg, treatment of overdose is mainly symptomatic treatment. Hemodialysis may not be effective because Bicalutamide is strongly protein bound.
3. Side effects of Bicalutamide fct 150mg
Common side effects of Bicalutamide fct 150mg include:
Anemia Anorexia Decreased libido Depression Dizziness Drowsiness Flushing Abdominal pain Constipation Indigestion Flatulence Nausea Liver toxicity Jaundice Increased transaminases Serum Erythema Hair loss Hirsutism / hair regrowth Dry skin Itching Hematuria Gynecomastia in men Erectile dysfunction Weakness Chest pain Edema Weight gain Uncommon side effects of Bicalutamide fct 150mg includes:
Hypersensitivity Angioedema Urticaria Interstitial lung disease Rare side effects of the drug Bicalutamide fct 150mg include:
Liver failure During the use of Bicalutamide fct 150mg, if you notice any unusual symptoms Usually, you need to immediately notify your doctor or go to a medical facility for timely medical assistance.
4. Interaction of Bicalutamide fct 150mg with other drugs
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Contraindicated concurrent use of Bicalutamide fct 150mg with the following drugs:
Terfenadine Astemizole Cisapride Caution should be taken when using Bicalutamide fct 150mg concomitantly with:
Ciclosporin Calcium channel blockers Drugs capable of inhibiting oxygenation chemicals such as cimetidine and ketoconazole. In theory, these drugs could increase blood levels of bicalutamide and possibly increase the side effects of this drug. Coumarin Anticoagulants: In vitro studies have shown that Bicalutamide competes with oral coumarin anticoagulants for plasma protein binding sites. Therefore, the prothrombin time test index should be closely monitored when initiating Bicalutamide fct 150 mg in patients taking coumarin anticoagulants. Bicalutamide fct 150mg is prepared in the form of film coated tablets with the main ingredient in each tablet is Bicalutamide 150mg. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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