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Aphabefex is manufactured and registered by 120 Armephaco Company Limited, Vietnam. With the main ingredients being iron fumarate and folic acid, Aphabefex is often used for the purpose of iron supplementation for the body.
1. What is Aphabefex?
Aphabefex drug belongs to the group of minerals and vitamins, with the main active ingredients being iron fumarate and folic acid.
Dosage form: Capsules, each containing 200mg of iron fumarate + 1mg of folic acid and excipients just enough.
Packing form: Currently, there are 3 forms: box of 3 blisters x 10 tablets, a bottle of 50 tablets or a bottle of 100 tablets with instructions for use inside.
2. Information about the ingredients in Aphabefex 200mg
2.1. Information about iron composition
Effect: Iron is an important micronutrient for the body. Iron plays an important role in the formation of hemoglobin in red blood cells, myoglobin in muscle and the respiratory enzyme cytochrome C. Therefore, iron products are often used in the treatment and prevention of iron-deficiency anemia.
2.2. Folic acid ingredient information
Pharmacodynamics: Folic acid, also known as vitamin B9.Pharmacokinetics:
Absorption and metabolism: In nature, folic acid exists in the form of polyglutamate. Once in the body, folic acid is hydrolyzed by the enzyme carboxypeptidase, reduced by DHR reductase and methylated to MDHR, and then absorbed into the bloodstream. Distribution: Folic acid is distributed in most body tissues, entering the cerebrospinal fluid, placenta and breast milk. Vitamin B9 is accumulated mainly in the liver and is highest in the cerebrospinal fluid. Elimination: Folic acid is excreted in the urine. Effects:
After oral administration, folic acid is converted to Tetrahydrofolate, which is an important coenzyme in many metabolic reactions. In it, there is a fusion of nucleoproteins and normal red blood cell formation. Therefore, folic acid deficiency causes megaloblastic anemia (similar to anemia caused by vitamin B12 deficiency). Convert Serin to Glycin, Deoxyuridylat to Thymidylate to form Thymin. In addition, folic acid also participates in a number of amino acid metabolism processes, format.
3. Indications of the drug Aphabefex
Aphabefex drug is used in the following cases:
Prophylaxis and treatment of iron deficiency anemia, iron supplementation; Used for subjects with high iron requirements such as pregnant women, breastfeeding, malnourished, after surgery, recovering from serious illness. Absolutely contraindicated in the following cases:
Allergy to any of the ingredients contained in Aphabefex; Hemolytic anemia ; Polycythemia vera ; Iron-infected liver disease.
4. Dosage and how to take Aphabefex
Always carefully read the information on the instruction leaflet for Aphabefex medicine attached in the box/vial. Absolutely follow the instructions of the doctor / pharmacist and do not arbitrarily increase, decrease the dose as well as change the route of administration to avoid harmful effects to health. You should not give A phabefex to other people even if they have the same symptoms as you.
Dosage:
For adults: 1-2 tablets/day x 1-2 times; For children: 1 tablet/day; Pregnant women: Take 1 tablet / day as soon as possible as soon as pregnancy is detected. How to handle when taking an overdose or forgetting a dose:
In case of an overdose: If you accidentally take an overdose, monitor your own health. If you notice any unusual symptoms, contact an emergency center immediately for assistance. You need to bring all the medicines and supplements you are taking, including prescription and over-the-counter medicines, vitamins, herbs, etc. If you miss a dose: Take another dose as soon as possible. when you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose as directed. Be careful not to take a double dose to make up for the missed dose.
5. Side effects of Aphabefex 200mg
During the treatment with Aphabefex 200mg, you may experience unwanted effects such as digestive disorders, change in stool color (black or dark gray),... In addition, you may experience the following: Other undesirable effects not listed. Tell your doctor or pharmacist right away if you experience any of these symptoms during your treatment with Aphabefex.
6. Drug interactions Drug interactions can reduce the effect or increase the toxicity of the drug. Therefore, tell your doctor if you are being treated with other medicines.
Drugs that may interact with Aphabefex include:
Cotrimoxazol : Reduces the effect of aphabefex in the treatment of megaloblastic anemia; Sulfasalazine and oral contraceptives: Decreased absorption of folic acid; Folic acid reduces blood levels of anticonvulsants; Concurrent use of antacids and oral iron may decrease iron absorption.
7. Some notes when using Aphabefex drug
People with normal blood iron levels should not take Aphabefex for a long time; Please discontinue use if intolerant to this product; Aphabefex 200mg is not a medicine, does not work to replace medicine; The effectiveness of Aphabefex 200mg may vary depending on the location of each subject; Storage: Aphabefex should be stored in a dry place, away from direct sunlight, out of reach of children and pets.
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