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Amnol drug belongs to the group of cardiovascular drugs, made in the form of film-coated tablets. With the main ingredient being Cilnidipine, Amnol will have specific uses and doses, please refer to the article below.
1. What are the effects of Amnol?
Amnol medicine contains the main ingredient is Cilnidipine combined with excipients just enough. The drug is prepared in the form of white, glossy tablets and stored in sealed film bags. This drug is indicated for the treatment of high blood pressure.2. Usage and recommended dosage
Amnol is absorbed through the oral route. Drink 1 time a day after each breakfast.
For adults: Take dose 5-10mg/time. Dosage will be adjusted according to the age and symptoms of the disease, can increase the dose to 20mg, taken once a day based on the doctor's prescription. For people with severe high blood pressure need to take a daily dose of 10-20 mg / time.
3. Cases in which Amnol should not be used
Do not use Amnol in the following cases:
The patient has a hypersensitivity reaction to any ingredient of the drug; Women who are pregnant or planning to become pregnant.
4. Possible side effects after using the drug
Amnol can cause some unwanted effects, but these are only rare cases encountered. If you unfortunately experience these side effects, stop taking the medicine and contact your doctor or go to the nearest medical center. Possible side effects such as:
Liver function disorder, jaundice; Thrombocytopenia (frequency < 0.1%). Some rare cases:
Increased AST (GOT), ALT (GPT), LDH....in the liver; Increased creatinine or urea nitrogen, positive renal proteinuria; Dull headache, dizziness when standing up, stiff shoulder muscles; Palpitations, feeling hot, abnormal electrocardiogram, low blood pressure; Digestive disorders, nausea, vomiting, abdominal pain; Increased or decreased white blood cells. neutrophils and hemoglobin ; Other adverse reactions: Edema of face, lower extremities, general malaise, diarrhea, increase in serum cholesterol, increase or decrease in CK (CPK), uric acid, potassium and phosphorus in serum, rash. Some rare cases:
Presence of sediment in the urine; Drowsiness, insomnia, tremors, forgetfulness; Chest pain, tachycardia, atrioventricular block, cold feeling; Constipation, abdominal distension, enlarged gums, heartburn, diarrhea; Changes in blood counts, which may increase or decrease red blood cells (RBC), hematocrit, eosinophils and lymphocytes; Fatigue, twin leg cramps, dry eyes, eye congestion and irritation, taste disturbances, positive urinary tract, total protein, serum calcium and CRP, fasting hyperglycemia or hypoglycemia , a cough.
5. Notes on drug interactions and incompatibilities
Before using the drug, you should tell your doctor or pharmacist if you are taking one of the following drugs, because they may interact with Amnol:
Should not be used with other antihypertensive drugs, because the additive effect can cause excessive lowering of blood pressure; Some calcium antagonists will increase plasma digoxin concentrations. If any sign of digoxin toxicity is detected, the digoxin dose should be adjusted or Amnol discontinued, depending on the patient's condition; Co-administration with Cimetidine will increase the absorption of calcium antagonists, because cimetidine reduces blood flow through the liver, prevents the metabolism of calcium antagonists by enzymes in the liver microsomes; Rifampicin will reduce the effect of calcium antagonists, because the drug metabolizing enzyme in the liver (cytochrome P450) by rifampIcin, promotes the metabolism of these drugs; Antifungal azole group such as itraconazole, miconazole,...: will increase Amnol plasma concentration, because antifungal azole group inhibits CYP3A4 drug-metabolizing enzyme for Amnol.
6. What to do in case of missed dose or overdose?
If you forget to take your medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue as scheduled.
Inform your doctor or pharmacist in case of overdose. If a marked drop in blood pressure occurs, first aid measures such as elevating the lower extremities or administering fluids and antihypertensive agents should be performed.
7. Be careful when using drugs
During the use of Amnol, patients should note:
For people with severe liver dysfunction, the drug concentration in the blood plasma may increase; In case of dose reduction, close monitoring is required. Do not arbitrarily stop taking the drug suddenly because it will aggravate some symptoms, if stopped, there should be other drugs instead; When the elderly use Amnol, the patient's condition should be carefully monitored and a low starting dose should be used to avoid excessive hypotension; There are no clinical studies demonstrating the use of Cilnidipine in children, so safety has not been established; Amnol can cause dizziness, lightheadedness due to low blood pressure, so care should be taken when driving and operating machinery. Amnol drug belongs to the group of cardiovascular drugs, prepared in the form of film-coated tablets. With the main ingredient is Cilnidipine, the drug is indicated for the treatment of hypertension.
To ensure effective treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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