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The drug Acerovax belongs to the group of cardiovascular drugs. So what is the use of Acerovax, and in what cases is it indicated for use?
1. What is Acerovax?
Acerovax medicine has the active ingredient Atorvastatin (in the form of Atorvastatin Calci) with a concentration of 20 mg, made in the form of film-coated tablets, presented in a box of 3 blisters, 1 blister has 10 tablets.
2. The effect of the drug Acerovax
The active ingredient Atorvastatin in Acerovax is a cholesterol-lowering substance. By inhibiting a cholesterol-producing enzyme called HMG - CoA reductase, the drug inhibits cholesterol production in the liver. The drug works to lower levels of total cholesterol as well as LDL cholesterol, which is considered a type of bad cholesterol that plays a major role in coronary heart disease. Lowering LDL cholesterol levels slows progression and may even reverse coronary heart disease in patients. In addition to LDL cholesterol, high blood triglyceride levels are also associated with coronary heart disease, unlike other drugs in the class, Atorvastatin can also lower blood levels of Triglycerides.Acerovax is indicated for use in the following cases:
Acerovax is indicated in reducing total cholesterol, LDL-cholesterol, triglycerides, apolipoprotein B and increasing HDL-cholesterol in patients with hypercholesterolemia. primary. Treatment of patients with betalipoproteinemia who have not responded adequately to the usual diet. In addition, Acerovax is also indicated to reduce LDL-cholesterol, total cholesterol in patients with homozygous familial hypercholesterolemia.
3. How to use and dose Acerovax
3.1. How to use Acerovax Drug Acerovax is prepared in the form of film-coated tablets, enteric-coated form, patients need to swallow the whole tablet without chewing, biting or crushing the tablet. Patients can use the drug at any time and the time to use the drug does not depend on the meal.
3.2. Dosage of the drug Acerovax In hypercholesterolemia (non- or heterozygous familial) and mixed dyslipidemia: the recommended starting dose of 10 - 20 mg once daily is recommended. In patients requiring significant reductions in LDL cholesterol levels (approximately more than 45%) may be initiated at a dose of 40 mg once daily. The therapeutic dose range of the drug that can be used is 10 to 80 mg, once a day.
Blood lipids should be checked and assessed 2 to 4 weeks after starting treatment or after increasing the dose of Acerovax so that the dose can be adjusted accordingly to meet the treatment needs of the patient. . In patients with homozygous familial hypercholesterolemia: 10 to 80 mg/day. In addition, it should be combined with other lipid-lowering measures.
Acerovax can be used in combination with Resin to increase the effectiveness of treatment.
In patients with renal impairment: no dose adjustment is required.
4. Undesirable effects of the drug Acerovax
Acerovax drug is well tolerated, so the side effects are usually only mild and transient, patients may experience unwanted effects when taking the drug such as: flatulence, constipation, indigestion, nausea, abdominal pain , vomiting, dizziness, headache.
Although the side effects will disappear when the patient stops using the drug, in order to achieve the best effect, it is recommended that patients experience any abnormal signs or symptoms immediately during treatment. doctor for prompt treatment.
5. Acerovax drug interactions
Must monitor prothrombin time in patients who are using Acerovax in combination with Indandione, anticoagulants because it will increase prothrombin time or bleeding time.
When taking Acerovax with drugs Erythromycin, Cyclosporine, Gemfibrozil, Niacin, immunosuppressive drugs cause an increased risk of myopathy in patients.
Digoxin concentrations may be slightly increased in serum when co-administered with Acerovax.
6. Note when using the drug Acerovax
6.1. Contraindications of the drug Acerovax Do not use Acerovax in the following subjects:
Patients with a history of hypersensitivity to Atorvastatin, HMG-CoA reductase inhibitors, or any of the excipients contained in Acerovax. Patients with persistently elevated serum transaminases or progressive liver disease of unknown etiology. Not for use by pregnant women and nursing mothers. 6.2. Precautions when using Acerovax It is necessary to exclude the causes of secondary dyslipidemia and measure the lipid indices before starting treatment with Acerovax. Quantification should be carried out periodically with an interval of not less than 4 weeks.
Patients must have a reasonable diet before starting treatment with Acerovax, need to maintain this diet during treatment and after treatment with the drug.
Caution should be exercised in patients who drink a lot of alcohol or have liver dysfunction.
During treatment with Acerovax or HMH-CoA inhibitors, if the patient has myositis, creatine kinase is increased, or the concentration of liver enzymes in the serum is 3 times higher than the sex. Within the normal range, it is necessary to reduce the dose or discontinue treatment with Acerovax.
7. Preservation of the drug Acerovax
Store Acerovax medicine in a cool, dry place, avoid direct exposure to sunlight or high temperature because these agents can cause the change of substances in the drug, storage temperature The appropriate level is below 30 degrees C.
The above is important information about Acerovax drug, before using, patients need to carefully read the instructions and follow the instructions of a specialist doctor to get the best treatment results.
