This is an automatically translated article.
The article was professionally consulted by Dr. Nguyen Anh Tu - Doctor of Obstetric Ultrasound - Prenatal Diagnosis - Obstetrics Department - Vinmec Hai Phong International General Hospital.Turner syndrome is the most common chromosomal disorder in women, causing a high rate of miscarriage, and babies born with many incurable developmental disorders. To prevent having a baby with Turner syndrome, high-risk women are advised to undergo prenatal screening.
1. What is Turner syndrome?
Turner syndrome occurs when part or all of an X chromosome in the human genome is lost.
According to research to date, Turner syndrome is the most common sex chromosome disorder in women, causing many developmental disorders both mentally and physically.
Normally, more than 90% of fetuses with Turner syndrome will have a spontaneous abortion, but still about 1 in 4000 girls are born with this syndrome. Currently, Turner syndrome can be detected early through prenatal screening in the fetus to prevent the birth of children with the disease.
2. Who should be screened for Turner syndrome in the fetus?
Subjects that need to be tested to detect Turner syndrome in the fetus are those suspected of having Turner syndrome or having high-risk pregnant women, such as being pregnant at an advanced age, having had a baby with Turner syndrome, or having a baby. There are abnormalities detected by ultrasound.
Not only screening for early detection of Turner syndrome, modern tests such as NIPT also help screen and detect early fetal malformations, other chromosomal abnormal syndromes such as Patau syndrome, Down syndrome ..
Doctors recommend pregnant women to perform prenatal screening, especially pregnant women in the following cases:
Pregnant women over 35 years old Married inbreeding Pregnant women with a family history of birth defects childbirth, Patau syndrome, Down... Pregnant women with a history of premature birth, miscarriage, unexplained stillbirth Pregnant women infected in the first 3 months of pregnancy: colds, rubella, medical diseases... Dad or mothers often have to work and live in toxic and chemical-laden environments.
3. Tests to detect Turner syndrome in the fetus
There are many test methods to help detect Turner syndrome in the fetus, in which the most commonly used tests are:
Karyotype test – Chromosome set up. QF-PCR test FISH test NIPT test: This is a modern method, newly applied but effective and safe. The fetal DNA test in maternal blood (NIPT) is a safe, non-invasive prenatal screening method with high accuracy in detecting Turner syndrome. NIPT test can be performed from the 10th week of pregnancy, only need to take 10-20 ml of mother's blood, without amniocentesis, placenta biopsy, so it is very safe. Therefore, the NIPT test is now widely used for early detection of Turner syndrome as well as many other chromosomal abnormalities and fetal malformations.
4. Where should I get the NIPT prenatal screening test?
The advanced NIPT prenatal screening test technique is currently being implemented at Vinmec International General Hospital, which has brought remarkable improvements in prenatal screening, helping to early and effectively intervene in fetuses with congenital abnormalities. Turner syndrome and other fetal malformations.
Vinmec gathers a team of experienced, well-trained experts in the country and in countries with the world's leading developed medicine such as Germany, UK, France. Doctors will give advice on genetic testing to customers before making a decision to do fetal NIPT.
Besides, Vinmec Gen Technology Center is also equipped with modern machinery system, giving outstanding fast, accurate and safe test results such as:
Automatic stem cell separation and storage system AXP – Thermogenesis and Bio-Archive Cleanroom systems meet standards Eppendorf centrifuges, Adiplus flowcytometer analyzers and cells Navios – Beckman Coulkter At the same time, Vinmec is also committed to providing customers with: Get a complete consultation about NIPT testing with a genetic pathologist. Customers will not receive results without genetic counseling. The process of taking and transporting blood samples containing mother and child DNA is guaranteed according to ISO 15189/2012 standard. Ensure privacy and confidentiality of customer information Clean laboratory system, modern equipment. Coverage assistance in case of false positive or negative results. Doctor Nguyen Anh Tu has 6 years of experience in obstetrics and gynecology ultrasound, specially researched and trained in fetal ultrasound - prenatal diagnosis. Dr. Tu has completed courses on ultrasound - prenatal diagnosis of the FMF International Fetal Medicine Association; trained in consulting and implementing diagnostic intervention techniques in fetal medicine and participated in many specialized conferences and seminars on Fetal Medicine. Currently a doctor at the Department of Obstetrics and Gynecology, Vinmec Hai Phong International General Hospital
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