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Accretropin is used as a growth hormone, used for pediatric growth hormone deficiency. Here are some effects, usage and precautions when using Accretropin.
1. What is the effect of Accretropin?
Accretropin is a recombinant human growth hormone indicated for the treatment of pediatric patients with growth failure due to insufficient secretion of normal endogenous growth hormone. Accretropin is also indicated for the treatment of short stature associated with Turner syndrome in pediatric patients presenting with aphasia.Accretropin has a sequence of effects on the body identical to that of human growth hormone derived from the pituitary gland. Natural human growth hormone is a protein produced by the pituitary gland, which acts on the ends of the long bones of the body, until the onset of puberty, and promotes growth to normal stature. A deficiency of this hormone in childhood leads to an unusually small stature.
Turner syndrome is an X-linked genetic disorder (sex chromosome) in girls that leads to short stature and infertility. The main use of Accretropin is to provide a growth hormone deficiency in children, to help treat growth failure in children with natural growth hormone deficiency, and to treat short stature associated with Turner Syndrome. .
2. How to take Accretropin
Accretropin is administered by subcutaneous injection. Your doctor, nurse, or other healthcare provider will give you the injection. You may also be taught how to give injections at home. Note that this medicine should not be used at home if you do not fully understand how to inject and dispose of the used needle and syringe.
How to inject Accretropin as follows:
Your doctor or nurse will show you some areas of your body where Accretropin can be injected. Use a different injection site in each injection. Do not inject this medication into an area of skin that is red, sore, infected, or injured; Select the injection site, disinfect the area you need to inject; Next, take the vial and gently rotate the cap to remove the cap. Do not shake the Accretropin vial as vigorous shaking may damage the medication. Note do not use the medicine if it has changed color or it has become cloudy; Take the needle and the medicine, then inject it into the site you disinfected earlier. Note that each needle is used only once. Throw used needles in the puncture-proof container. During treatment to be sure that this medicine helps your condition and is not harmful to your body. Your blood tests and growth progress will need to be checked regularly.
Storage Notes: Accretropin should be stored in the refrigerator. Avoid freezing and shaking. Do not use after the expiration date indicated on the box and vial labels.
Once opened, Accretropin can be stored for up to 14 days in the refrigerator.
3. When is Accretropin contraindicated?
You must not use Accretropin in the following cases:
Do not use this medicine if you are allergic to Accretropin or to other ingredients of the drug; Diabetic retinopathy: This is a serious eye condition caused by diabetes; Prader-Willi syndrome, being overweight or obese, sleep apnea or severe breathing problems. Accretropin should be delayed if you have a serious medical condition such as:
Recent open heart surgery or gastric bypass surgery; Having an injury or other medical emergency; respiratory failure . 4. Side effects when taking Accretropin Side effects that may occur during treatment with Accretropin include:
Serious side effects: It is a severe allergic reaction including signs such as a rash; shortness of breath; swelling of the face, swelling of the lips, tongue or throat, fast heartbeat, loss of consciousness... you need emergency medical help; Some other serious side effects, if they occur, call your doctor right away. These serious side effects include: Pain that comes on suddenly and is severe, pain in the upper abdomen; nausea, vomiting, excessive sweating, fever, fast heartbeat, yellowing of the skin or eyes; increased thirst and increased urination; sudden and severe pain in the back of your eye, vision changes; swelling in the head, face, hands, or feet; numbness or tingling in the wrists, hands, or fingers; Less serious side effects that may be experienced include: Headache ; redness, soreness, rash on the skin, itching, pain, or bruising at the injection site; breast development; pain, swelling, or stiffness; mild nausea, stomach pain, flatulence.
5. Notes when using Accretropin
Before taking the medicine you need to tell your doctor about your history of liver disease, kidney disease, diabetes, scoliosis, high blood pressure, pancreatic disorder, cancer, carpal tunnel syndrome, thyroid disease, tumor brain, allergic condition. If you have any of these conditions, you may need a dose adjustment or special tests to use Accretropin; If you have Prader-Willi syndrome, call your doctor right away if you develop signs of lung or breathing problems such as difficulty breathing, coughing, or snoring. Rare cases of serious breathing problems have occurred in patients with Prader-Willi syndrome using Accretropin; Accretropin may harm an unborn baby. You should tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether Accretropin passes into breast milk or harms a nursing infant. So do not use Accretropin if you are breast-feeding; Use Accretropin exactly as directed by your doctor. Do not arbitrarily use Accretropin in larger amounts or for longer than recommended by your doctor; If I miss a dose: Use the medicine as soon as you remember. If it is almost time for your next dose, skip the missed dose and use the scheduled dose. Do not take a double dose, tell your doctor if you forget more than 3 doses in a row. Overdose may cause symptoms such as tremors, cold sweats, increased hunger, headache, excessive drowsiness, weakness, dizziness, heart palpitations and nausea. Long-term overdose symptoms may include excessive growth. You should notify your doctor as soon as you notice signs of an overdose. Drug interactions can happen, so before using Accretropin, tell your doctor if you use insulin or oral medications to treat diabetes. Accretropin affects blood sugar levels and may require an adjustment in the dose of your diabetes medication. Oral diabetes medications include Acetohexamide (Dymelor), Chlorpropamide (Diabinese), Glimepiride (Amaryl), Glipizide (Glucotrol), Tolazamide (Tolinase), and Tolbutamide (Orinase). Interactions with steroid medications such as Cortisone, Methylprednisolone (Medrol), Prednisone, and Dexamethasone (Decadron) can make Accretropin less effective. But absolutely do not arbitrarily stop taking steroids because it is dangerous to the body and do not change the dose yourself. It is necessary to follow the instructions of the doctor. Also, other over-the-counter medications can interact, so tell your doctor about all prescription and over-the-counter medications, including vitamins, minerals, and herbal products. and other prescription drugs. Above is some information you need to know about Accretropin drug. Accretropin is a growth hormone-like drug and should be taken with caution. Always consult your doctor before and while taking medication.
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Reference source: drugs.com
