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Myderison is a muscle relaxant, used in the treatment of muscle hypertonia in certain medical conditions. Is Myderison medicine safe, what are the side effects of Myderison 50mg medicine?
1. The effect of the drug Myderison 50mg
Myderison drug belongs to the group of muscle relaxants, is made in the form of film-coated tablets, with the main ingredient in each tablet is Tolperisone Hydrochloride 50mg.
Tolperison is a centrally acting muscle relaxant. Thanks to its membrane stabilizing and local anesthetic properties, tolperison inhibits conduction in primary nerve fibers and motor neurons, thereby inhibiting polysynaptic and monosynaptic reflexes.
On the other hand, tolperison also inhibits Ca2+ influx into the synapse. Experts believe that this substance inhibits the release of neurotransmitters. In the brain stem, tolperison inhibits the reticular–spinal reflex. In various experimental animal models, Myderison was able to reduce increased muscle tone and spasticity that occurs after brain loss.
Tolperison also works to improve peripheral circulation. This effect is independent of the drug's CNS effects and may be related to tolperison's mild antispasmodic and anti-adrenergic effects.
Myderison drug is indicated in the following cases:
Pathological skeletal muscle hypertonia in organic neurological disorders such as: pyramidal damage, cerebrovascular accident, spinal cord disease, encephalitis, multiple atheroma,... Increased muscle tone, muscle spasms and spasms accompanied by movement diseases such as spondylosis, spondyloarthritis, lumbar and neck syndromes, joint diseases of the joints large joints. Rehabilitation after trauma surgery - orthopedic. Treatment of thromboembolic diseases such as atherosclerosis, diabetic vascular disease, thromboembolic vasculitis, Raynaud's disease, disseminated scleroderma. The syndromes appear due to impaired neuro-vascular distribution such as cyanosis of the extremities, dyskinesia due to neuro-vascular disorders. Myderison drug is contraindicated in the following cases:
People with hypersensitivity to tolperison or substances structurally similar to eperison or any component of the drug. Mechanical disadvantage.
2. Dosage and how to take Myderison
Myderison is used orally, it should be taken with a meal or right after eating. The dose of Myderison should be according to the doctor's prescription, the reference dose is as follows:
Adults use a dose of 150 - 450mg / day, divided into 3 equal parts depending on the needs and tolerability of each patient. . Children under 6 years of age can use a dose of 5 mg/kg body weight/day, the total dose is divided into 3 equal parts. Children from 6-14 years old, use a dose of 2-4 mg/kg body weight/day, this total dose is divided into 3 equal parts. Data on overdose with Myderison are rare. Tolperison has a wide therapeutic dose range. The highest daily dose of Myderison recorded in the literature was up to 600 mg without causing any serious symptoms of toxicity.
Irritation has been observed after giving children a dose of 300 - 600 mg a day. In acute preclinical toxicity studies, high doses of tolperisone have been associated with ataxia, tonic-clonic seizures, dyspnea, and respiratory paralysis. There is no specific antidote for Myderison, if overdose occurs, supportive and symptomatic treatment should be given.
3. Myderison 50mg side effects
The side effects encountered when using Myderison drugs are mainly manifestations on the skin, subcutaneous tissue, systemic disorders, disorders on the nervous system and digestive disorders.
Side effects of Myderison 50mg include:
Hypersensitivity reactions: Most of these reactions are not serious and are reversible on their own. Very rarely, hypersensitivity reactions to Myderison may be life-threatening. Confusion is very rare. Hyperhidrosis is rare. If you experience any side effects of Myderison, notify your doctor immediately or go to the nearest medical facility for timely treatment.
Hopefully, the above sharing will help you better understand how to use Myderison 50mg to have the most effectiveness in disease treatment and ensure health.
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