Progynova is utilized in hormone replacement therapy for the treatment of menstrual irregularities and the prevention of postmenopausal osteoporosis. Therefore, the questions arise: How long after commencing Progynova treatment does menstruation occur? Does the use of Progynova induce ovulation? And is pregnancy possible while taking Progynova?
1. How long after taking Progynova to menstruate?
The main component of Progynova is Estradiol valerate, a precursor of the naturally occurring 17β-estradiol in the human body. Some tablets also contain norgestrel, a progestogen.
With its specific composition and regular usage regimen, Progynova involves using estrogen alone for 11 days and a combination of estrogen and progesterone for 10 days, followed by a 7-day break from taking the medication. You will experience a normal menstrual cycle in this case, provided your uterus is intact.
2. Does the use of Progynova induce ovulation?
While ovulation is typically not inhibited during the administration of Progynova, the production of endogenous hormones is substantially influenced. Progynova may be prescribed for younger women to induce and regulate menstrual cycles. Furthermore, it is employed in the management of dysfunctional uterine bleeding in the perimenopausal period.
3. Can I get pregnant by taking Progynova?
Progynova is contraindicated in pregnant women. In the event of pregnancy occurring during Progynova use, the medication should be discontinued immediately. Progynova is not indicated for contraception.
4. Indications and contraindications of Progynova
Progynova is one of the medications used in hormone replacement therapy (HRT) for:
- Treating patients with signs and symptoms of estrogen deficiency due to natural menopause or hypogonadism.
- Preventing postmenopausal osteoporosis.
- Progynova is contraindicated for the following cases:
- Pregnant and lactating women.
- Undiagnosed vaginal bleeding
- Known or suspected breast cancer
- Presence or suspicion of uterine tumor whether benign or malignant, due to the influence of sex hormones.
- Current or past history of liver tumors
- Severe liver disease/impairment
- Active arterial thromboembolic disease such as myocardial infarction (heart attack) or stroke
- Active deep vein thrombosis (DVT) with thromboembolism or a history of these conditions
- High risk of arterial or venous thromboembolism
- Severe hypertriglyceridemia.
- History of hypersensitivity to any of the ingredients of the medication
5. Progynova usage
For patients who have had a hysterectomy, the drug can be taken at any time.
If the patient still has an intact uterus and is still menstruating, treatment with a combination of Progynova and progesterone should begin within the first 5 days of the menstrual cycle.
Patients with amenorrhea or irregular menstrual cycles and after menopause can initiate combination therapy at any time, but the possibility of pregnancy must be excluded during treatment.
Women changing from another HRT regimen should use the full therapeutic dose before starting Progynova.
Each pack of Progynova contains 28 tablets for 28 days of treatment. Treatment is continuous, meaning that after you finish one pack, you should start the next pack immediately without any break.
Progynova should be swallowed whole with a little water. The medicine should be taken at a fixed time every day.
In case of a missed dose, you should take the missed tablet as soon as possible. If you have missed the dose by more than 24 hours, do not take the missed tablet. If you miss several tablets, irregular bleeding may occur.
During the use of Progynova, you may encounter some side effects including:
- Weight gain or loss;
- Headache;
- Abdominal pain;
- Nausea;
- Rash;
- Itching;
- Hypersensitivity;
- Depression ;
- Dizzy;
- Vision disturbances;
- Rapid heartbeat;
- Diarrhea;
- Hives
- Breast pain or tenderness ;
- Unusual vaginal bleeding.
These are not all the possible side effects of Progynova. If you have any unusual symptoms while using Progynova, please notify your doctor immediately for timely treatment.
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