Uses of the drug Cravit Tab 500

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Cravit Tab is made in the form of tablets with 2 strengths of 250 and 500mg. Levofloxacin is a drug that specializes in the treatment of mild - moderate - severe infections caused by susceptible strains.

1. What is Cravit Tab 500?


Cravit Tab 500 has the main ingredient Levofloxacin 500mg. This active ingredient is indicated for the treatment of infections caused by strains susceptible to Levofloxacin. Specifically:
Acute sinusitis ; Acute exacerbation of chronic bronchitis ; Community-acquired pneumonia ; Urinary tract infections with and without complications; Nephritis - acute pyelonephritis ; Skin and soft tissue infections.

2. Instructions on how to take Cravit Tab


Cravit Tab 500 is used to treat mild, moderate & severe infections in adults over 18 years of age. The recommended drug dosage is as follows:
Treatment of acute sinusitis: Take 500mg/day, maintain from 10-14 days; Treatment of exacerbations of chronic bronchitis: Take from 250-500mg/day; maintain from 7-10 days; Treatment of community-acquired pneumonia: 500mg/time x 1-2 times/day; maintain drug use from 7-14 days; Treatment of urinary tract infections with or without complications: Oral 250mg/day; maintain medication for 7-10 days; Treatment of skin & soft tissue infections: Take 500mg/time x 1-2 times/day; Maintain medication for 7-14 days. Note:
For patients with hepatic impairment and the elderly, no dose adjustment is required (except in cases where renal function should be considered); Patients with renal impairment (ClCr < 50mL/min): Consider dose reduction on medical advice; Cravit Tab is not affected by food, so it can be taken without regard to meals; Adequate hydration should be given to patients taking Cravit Tab tablets to prevent the formation of concentrated urine. Crystals in urine and casts have been reported with Quinolone administration.

3. Side effects of the drug Cravit Tab


During the treatment of infections with Cravit Tab, users may experience the following problems:
Possible reactions: Nausea, vomiting, taste changes, diarrhea, sleep disturbances (loss of appetite). sleep), dizziness headache; Rarely: Painful swelling of joints/muscles/tendons; abdominal pain, vision changes, allergic reactions, sensitivity to sunlight; Very rare reactions: Mental confusion, seizures, cardiac arrhythmias, chest pain, anxiety, change in urine output, yellow eyes, jaundice, signs of superinfection with prolonged use.

4. Notes when using Cravit Tab


Contraindications to taking Cravit Tab for the following cases:
Hypersensitivity to drug components (especially Levofloxacin, Ofloxacin), Quinolone group drugs; Children and adolescents (<18 years old); Pregnant & lactating women; Patients with epilepsy; People with a history of tendon disorders (pain) caused by fluoroquinolone antibiotics; At the same time, use Cravit Tab with caution in the following cases:
Patients with impaired renal function; Have or are suspected of having a neurological disorder that may cause seizures; Diabetics who are taking in combination with blood glucose-lowering drugs (especially with insulin or sulfonylurea drugs); Patients with severe heart disease such as: arrhythmia, myocardial ischemia (possibly with QT prolongation), patients with uncorrected electrolyte imbalance (such as hypomagnesemia, hypokalemia), patients taking class IA and III antiarrhythmic drugs; The patient has severe myasthenia gravis.

5. Drug interactions of Cravit Tab


Cravit Tab may interact with the following drugs:
Antacids containing Magnesium, Aluminum, Sucralfate, Iron and multi-vitamin preparations containing zinc. Therefore, it is necessary to take Cravit Tab 2 hours before; Theophyllin: It is necessary to monitor the Theophylline concentration closely and adjust the dose of Cravit Tab accordingly to avoid unwanted side effects due to increased plasma concentrations of Theophyllin; Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Levofloxacin in Cravit Tab with NSAIDs may increase the risk of CNS irritation and convulsions; Anti-diabetic drugs: Patients who combine quinolones with anti-diabetic drugs may have an increased risk of dysglycemia (hyperglycemia/hypoglycemia). To avoid this, it is necessary to monitor blood glucose levels carefully when using the combination of these two drugs; Anticoagulants (Wafarin): Co-administration with Cravit Tab may increase the inhibitory hepatic metabolism of Warfarin, thereby prolonging Prothrombin time; Class IA antiarrhythmic drugs (such as Procainamide Hydrochloride or Quinidine Sulfate) and class III antiarrhythmic drugs (such as Sotalol hydrochloride and Amiodarone Hydrochloride): If used in combination with Cravit Tab may cause prolongation of the QT interval; Didanosin: It has been reported that Didanosin may decrease the absorption of Levofloxacin. Therefore, it is necessary to take Cravit Tab at least 2 hours before or after taking Didanosin; Antidepressants: Levofloxacin used in combination with imipramine may increase the effect of prolonging the QT interval. In order to be safer for their own health and good for the treatment process, in addition to referring to the above information, patients should also actively consult their doctors and pharmacists before taking Cravit Tab.

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