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Utrogestan 200 mg is a drug used to supplement female hormones in cases of deficiency or other problems due to hormonal disorders. To learn more about the effects of the drug, please refer to the article below.
1. What is the effect of Utrogestan 200mg?
Utrogestan medicine 200mg has the main ingredient is progesterone 200mg. Utrogestan contains the hormone progesterone in the form of fine granules, which can be administered orally and vaginally, both of which significantly increase plasma progesterone concentrations. Therefore, the drug helps to effectively supplement in cases of progesterone deficiency.
Utrogestan 200mg drug is used in the following cases:
Treatment in gynecological diseases: Disorders related to progesterone deficiency such as premenstrual syndrome, menstrual irregularities due to ovulation disorders or due to progesterone deficiency. anovulation, benign mammary gland disease, perimenopause. Menopause: Complementary to estrogen therapy. Infertility: Used in cases of primary or secondary infertility due to partial or complete failure of the corpus luteum, especially in cases of ovulation disorders, supplementing the luteal phase in egg donation. Treatment in obstetrics: Used to treat cases of threatened miscarriage, to prevent the risk of recurrent miscarriage due to luteal insufficiency, threatened preterm birth.
2. Usage and dosage of the drug Utrogestan 200Mg
How to use: The drug can be taken orally or through vaginal application. Depending on the intended use in any case, different routes can be used.
Dosage:
For oral administration: The usual dose is 200-300 mg of progesterone per day, usually in 1 to 2 divided doses. You take about 200 mg in the evening before going to bed and take another 100 mg in the morning if needed.
In case of luteal insufficiency (premenstrual syndrome, benign breast disease, irregular menstruation, perimenopause): Treatment with the usual dose of about 10 days per cycle is usually administered from day 17 to Day 26. In hormone replacement therapy: If estrogen alone is not appropriate, progesterone is used in combination for the last 2 weeks of treatment, followed by discontinuation of all hormone replacement therapy for approximately 1 week. . Note that during that time there may be bleeding when stopping the drug. In case of threatened preterm birth: 400mg progesterone (2 Utrogestan tablets) every 6-8 hours depending on the clinical results of the pregnant woman in the acute phase, followed by a maintenance dose of 200mg/times and 3 times a day. up to the 36th week of pregnancy. Vaginal: The usual dose is 200 mg of progesterone per day (1 Utrogestan 200 mg tablet) inserted deep into the vagina. This dose may be increased according to individual patient response.
In case of partial deficiency of the luteal phase due to ovulatory disorders, irregular menstruation: 200 mg of progesterone per day, taken for 10 days for each cycle, usually starting from day 17 to day 26. Infertility due to complete luteal phase deficiency: Initial dose of 100mg progesterone on days 13 and 14 of the embryo transfer cycle, followed by 100mg of progesterone in the morning and evening from day 15 until the end of the day 25th of the cycle. From day 26 onwards and in the case of pregnancy, increase the dose to 100 mg of progesterone/day every week to a maximum dose of 600 mg of progesterone/day given in 3 divided doses. Maintain this high dose until day 60. Luteal phase supplementation in IVF: Initiate the evening of embryo transfer with a high dose of 600 mg of progesterone per day in 3 divided doses. Threatened miscarriage or prevention of recurrent miscarriage: Take a fatal dose of 200mg to 400mg of progesterone per day in 2 divided doses until the 12th week of pregnancy.
3. Side effects when taking Utrogestan 200mg
When using the drug Utrogestan 200mg may experience side effects, including:
Common: Causes menstrual cycle changes, amenorrhea, bleeding between menstrual cycles; Headaches may also occur. Uncommon side effects: Drowsiness, dizziness; cholestatic jaundice, itching, digestive disorders. When experiencing side effects when taking the drug, you need to stop using it and notify your doctor for advice and timely treatment.
4. Note when using Utrogestan 200mg
Utrogestan 200mg drug is contraindicated in cases of severe liver failure, allergy or hypersensitivity reaction to the active substance or to any of its ingredients. Note that this medicine is used but does not prevent pregnancy. The drug can also be given to pregnant women. Overdose: Normally, when you take it vaginally, no cases of overdose have been recorded. Oral overdose can cause effects similar to side effects. In case of dose reduction, the symptoms will almost automatically disappear. In some patients, taking the drug at the usual dose may also be too high, manifested by increased hypersensitivity to the drug or accompanied by low blood levels of oestradiol. In these patients, the dose should be reduced or progesterone administered at bedtime. In the case of light bleeding or a shortened menstrual cycle, treatment should be started later than in the normal cycle, for example it should be started on day 19 instead of day 17. When you forget a dose, or add a dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue as usual. Do not take a double dose to make up for a missed dose. In the case of women with uterine bleeding, Utrogestan should not be used until the cause of the bleeding has been determined, as by endometrial examination. Because the risks of thromboembolism and metabolism cannot be completely excluded, treatment should be discontinued in the following cases: Eye disorders such as loss of vision, diplopia, damage to retinal blood vessels. Venous embolism or thromboembolism, regardless of location. The patient had a severe headache while taking it. Closer examination is recommended in patients with a history of thrombophlebitis. Note: More than half of spontaneous early miscarriages due to genetic complications, infectious phenomena or mechanical disorders can cause miscarriage, premature delivery. In these cases, if you take progesterone, it only slows down the discharge of dead eggs. Therefore, progesterone alone should be reserved for cases of insufficient luteal secretion. For operating machinery, driving: May be affected by when taking this drug can cause drowsiness, dizziness if taken orally, should pay attention to driving or using machines. To avoid side effects of the drug, you should take the drug in the evening. There are no specific studies on whether progesterone is excreted in human milk, so it is best to avoid using the drug in women who are breastfeeding. Drug Interactions: Concomitant use of this drug with other drugs may affect the metabolism of progesterone, possibly altering the effectiveness of some drugs. In addition, progestins can decrease the uptake of glucose into the cells, so that in patients with diabetes there will be an increased need for insulin and other antidiabetic agents. Do not use the medicine after the expiry date, show signs of damage, store the medicine at a temperature below 30°C and keep it out of the reach of children. The above are the effects of the drug Utrogestan and the notes when using the drug. The drug is used under the prescription of an obstetrician, you do not arbitrarily use the drug without being prescribed. To avoid harm to the body.
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