What is Bihasal 2.5?

Bihasal 2.5 is a cardiovascular drug indicated in the treatment of mild to moderate hypertensive disease, supporting the treatment of stable chronic heart failure. So what is Bihasal 2.5?

What is Bihasal 2.5? Bihasal 2.5 contains the active ingredient bisoprolol fumarate 2.5mg, which belongs to the group of cardiovascular drugs. What diseases does Bihasal 2.5 treat? Bihasal can be used as monotherapy or in combination with other antihypertensive drugs, especially antihypertensive drugs.
In addition, some other effects of the drug are not listed on the approved drug label, but in some cases the doctor may prescribe the use of Bihasal 2.5. Therefore, before taking the medicine, consult your doctor.

Bihasal 2.5 is prepared in the form of film-coated tablets with a dosage of 2.5mg. Dosage will be based on the condition and age of the patient.
For hypertension or angina, the usual starting dose is 2.5mg-5mg/time/day, and the maximum recommended dose is 20mg/time/day. Stable chronic heart failure: Bihasal 2.5 is often used in combination with other drugs. The starting dose is 1.25mg/time/day. If well tolerated, the dose should be doubled after 1 week, then gradually increased after 1-4 weeks until the maximum tolerated dose is reached, but not exceeding 10 mg/day. The specific dosage is as follows: In a week if well tolerated, increase the dose by 1.25mg/time/day In the following week, if well tolerated, increase the dose by 2.5mg/day/time In the next week if tolerated If good, increase dose 3.75mg/day/time In the next 4 weeks if well tolerated, increase dose by 5mg/day/time In the next 4 weeks if well tolerated, increase dose by 7.5mg/time/day is 10mg/day Patients can use the drug with or without food, before or after eating. However, to reduce stomach irritation you can take it with food and need to swallow the tablet whole with a full glass of water, do not chew or break the tablet.
To use the drug safely, take Bihasal 2.5 exactly as directed by your doctor, do not use more than the recommended dose, smaller or longer than prescribed. Use Bihasal 2.5 regularly to get the most benefit from it and you can stop taking it if any new symptoms appear or the condition does not improve after 7 days. Patients absolutely do not abuse the drug for too long for a long time. This does not make the patient's condition better, but also increases the risk of unwanted effects.

Bihasal 2.5 medicine can cause some unwanted and common side effects that can be mentioned as:
Diarrhea Nausea, vomiting Rhinitis Asthenia Fatigue Feeling cold or numb hands and feet Digestive disorders When At the beginning of treatment, there is usually a feeling of dizziness, fatigue, headache, dizziness, etc. These symptoms are usually less severe and will go away within 1-2 weeks after starting treatment. Some less common side effects include: paresthesia, drowsiness, decreased tactile sensation, anxiety, restlessness, memory loss, energy, dry mouth, nervousness, bradycardia, loss of balance, cold head, inflammation bladder, rash. Before prescribing drugs, doctors always consider the benefits and effectiveness of Bihasal 2.5. When using Bihasal 2.5 can still occur unwanted effects. Therefore, when unusual symptoms are present, especially when a severe allergic reaction occurs with accompanying signs such as severe dizziness, difficulty breathing, rash, anxiety, cognitive impairment , respiratory failure and coma, the patient should immediately notify the doctor or nurse for immediate medical intervention.

Some notes when using Bihasal 2.5 include:
Report a history of allergy to Bihasal 2.5 or other drugs that block hypersensitivity reactions with any other allergies. Bihasal 2.5 may contain ingredients that are inactive and could cause allergic reactions or other serious problems. Report any medications you are taking including prescription and nonprescription drugs, herbal and dietary supplements, foods, dyes or preservatives. Bihasal 2.5 is contraindicated in patients with acute heart failure and decompensated heart failure who require intravenous infusion of drugs that cause myocardial contractility, cardiac conduction disturbances, cardiogenic shock, bradycardia less than 69 beats/min before treatment. Starting treatment, ... Bihasal 2.5 should be used with caution in patients with chest pain at rest, asthma or other lung diseases, diabetes, untreated heart failure, psoriasis, peripheral arterial occlusive disease. border,... When starting treatment with Bihasal 2.5 drug should be under regular medical supervision within 3 months. For pregnant women, when taking Bihasal 2.5, there is a risk of harm to the fetus, so it is necessary to consult a doctor before use to weigh the benefits and risks. During lactation, the use of Bihasal 2.5 is not recommended. If you forget to take a dose of Bihasal 2.5, take it as soon as possible. However, if it is close to the time of your next dose, skip the missed dose and continue taking or injecting the medicine as scheduled. Do not use more drug than the treatment regimen. Overdose of Bihasal 2.5 or swallowed can cause serious symptoms such as bradycardia, heart block, hypotension, congestive heart failure, bronchospasm, and hypoglycemia, etc. Bihasal 2.5 should be stopped immediately.
If the heart rate is slow, atropine should be given intravenously, if the patient does not respond, it may be prudent to use isoproterenol or some other drug that increases heart rate. In some cases, a temporary pacemaker must be placed to stimulate an increase in heart rate. Hypotension: intravenous fluids and antihypertensive drugs. Glucagon can be given intravenously. Cardiac block (grade II or III): carefully monitor the patient and administer isoproterenol or pacemaker implantation. Congestive heart failure: carry out the usual measures (using digitalis, inotropes, diuretics, vasodilators). Bronchospasm: use bronchodilators such as isoproterenol and/or aminophyline. Hypoglycaemia: Intravenous glucose.

Drug interactions can reduce the effect of Bihasal 2.5, or increase the effect of unwanted effects. Some drugs that may interact with Bihasal 2.5 include:
Cardiovascular drugs may enhance the antihypertensive effect of Bihasal 2.5 or may affect heart rate, muscle tone, conduction, and conduction. Cardiac infusion such as: calcium channel blockers diltiazem, verapamil, nifedipine Medicines for Parkinson's disease and depression may enhance the blood pressure lowering effect of Bihasal 2.5, but there is also a risk of a sudden rise in blood pressure such as monoamine oxidase inhibitors. except MAO-B Drugs containing clonidine: hypertension may occur as well as excessive reduction of heart rate and cardiac conduction Antiarrhythmic drugs acting on cardiac conduction and increasing heart rate: disopyramide, amiodarone, quinidine Some Drugs containing parasympathomimetic agents including tacrine: cardiac conduction system may be affected. Beta-blockers including eye drops Diabetic medications that can mask signs of low blood sugar such as a rapid pulse: insulin or oral antidiabetic drugs. Anesthesia used in surgery: because cardiac activity can be reduced during anesthesia. Drugs containing digitalis glycosides: heart rate and cardiac conduction system may be affected. Analgesic or anti-inflammatory drugs: due to the hypotensive effect may be reduced Ergotamine derivatives: peripheral blood supply may be reduced Sympathomimetics such as eye drops, cough drops, nasal drops may decrease The effect of the drug Bihasal 2.5 . Other antihypertensive drugs Drugs to treat epilepsy such as barbiturates, psychotropic drugs such as tricyclic antidepressants, phenothiazines increase the antihypertensive effect of Bihasal 2.5. Rifampicin interferes with the duration of action of Bihasal 2.5 but usually does not require dose adjustment of Metloquin: increased effect on heart rate of bisoprolol.

Store Bihasal 2.5 with film-coated tablets at room temperature below 30 degrees Celsius, protect from light and avoid humid places. Do not store Bihasal 2.5 in a humid place or in the freezer and keep away from heat and open flames. Different medicines will have different storage methods, so read carefully the storage instructions for Bihasal 2.5 on the package, or ask your pharmacist. Keep Bihasal 2.5 out of the reach of children and family pets. When the medicine has expired or is damaged and cannot be used anymore, dispose of it and dispose of it properly. Do not arbitrarily dispose of Bihasal 2.5 in the environment such as plumbing or toilet unless requested. Please consult your waste management company or pharmacist on how to safely dispose of Bihasal 2.5 to help protect the environment.
In summary, Bihasal 2.5 is effective in the treatment of many cardiovascular diseases. However, Bihasal 2.5 can cause some unwanted effects and drug interactions, so tell your doctor what medicines you are taking to reduce the risk of unwanted effects and at the same time increase the effectiveness of the treatment.