Uses of Korantrec

Korantrec is prepared in the form of tablets with the main ingredient in each tablet is 5mg Enalapril maleate with Korantrec 5 and 10mg Enalapril maleate with Korantrec 10. So what does Korantrec do and how to use it?

Enalapril in Korantrec has an effect on the renin - angiotensin - aldosterone system, it inhibits the ACE of this system. Thereby reducing the resistance of peripheral arteries.
In heart failure, Enalapril maleate is effective in reducing preload and afterload, cardiac output can be increased without significantly affecting heart rate.
Long-term treatment with Enalapril reduces hypertrophy, reduces symptoms and severity of heart failure, and increases exercise tolerance.
Korantrec drug is indicated in the following cases:
Idiopathic hypertension of different degrees. Hypertension due to kidney disease. Hypertension with diabetes. Levels of heart failure: Helps improve survival, slow down the progression of heart failure, reduce the number of heart attacks. Treatment and prevention of congestive heart failure. Prevention of ventricular dilatation after myocardial infarction. Korantrec is contraindicated in the following cases:
People who are sensitive to enalapril. Aortic stenosis. Renal artery stenosis. Precautions while using Korantrec:
Korantrec contains lactose, so you must let your doctor know if you are intolerant to certain types of sugar. Do not take Korantrec during pregnancy. Enalapril in Korantrec passes into breast milk, but the effect of the drug on the nursing infant has not been determined, so Korantrec should not be used while breastfeeding. Sometimes Korantrec causes dizziness and fatigue, so you should be careful when driving and operating machines.

Korantrec is to be taken orally, taking it with a sufficient amount of water. Korantrec can be taken before or after meals, because food does not change the bioavailability of the drug.
Dosage of Korantrec drug should be according to the doctor's prescription, the reference dose in specific cases is as follows:
Primary hypertension: The usual starting dose is 5mg, the dose can be increased depending on the level of blood pressure. In hypertension, maintenance dose is determined after 2-4 weeks of treatment. The daily maintenance dose is usually 10-40mg, taken once a day or in two divided doses. The maximum dose of Korantrec is 40mg/day. Korantrec should be started at a low dose because it can cause symptoms of hypotension, and should not be used at the same time as diuretics. In case of renal failure: Creatinine clearance 30-80ml/min, use dose 5-10mg/day. Creatinine clearance 10-30ml/min, used dose 2.5-5mg/day. Heart failure: Often combined with Digitalis and diuretics, the dose of diuretics should be reduced and oral before taking Korantrec. Korantrec is used at a starting dose of 2.5 mg, which can be gradually increased to a therapeutic dose, but should be done under the careful supervision of a physician.

During the use of Korantrec, you may encounter some side effects of the drug, including:
Anemia; Aplastic anemia; Hemolytic anemia; Decrease in neutrophils; Decrease in hemoglobin; Reduce hematocrit; Thrombocytopenia; Agranulocytosis; Bone marrow suppression; Decreased total platelet count; Lymphatic disease; Autoimmune disease; Reduce blood glucose; Headache; Depression ; Confusion; Sleepy; Insomnia; Upset; Paresthesias; Dizzy; Unusual dreams; Sleep disorders ; Blurred vision; Dizzy; Hypotension including orthostatic hypotension; Faint; Heart attack ; Fast heart beat; Stroke; Chest tightness; Arrhythmia; Angina pain; Palpitations; Raynaud's phenomenon; A cough; Shortness of breath; Runny nose; Quinsy; Hoarseness ; Bronchospasm/asthma; Pulmonary infiltrates; Rhinitis; Allergic alveolitis/eosinophilic pneumonitis; Nausea, vomiting; Diarrhea ; Stomachache; Change in taste; Bowel obstruction; Pancreatitis; Undigested; Constipation ; Loss of appetite; Stomach irritation; Dry mouth; Stomach ulcers ; Mouth Sores; Abscess; laryngitis; Liver failure; Hepatitis ; Cholestasis; Rash; Hypersensitivity; Angioedema; Itchy; Hives; Hair loss; Erythema multiforme; Stevens-Johnson syndrome ; Scaly eczema; Epidermolysis due to toxicity; pemphigoid erythema; A complex of reported symptoms includes: Fever, vasculitis, serosa, myalgia/myalgia, arthralgia/arthritis, positive ANA, leukocytosis, eosinophilia; Liver failure; CKD; Proteinuria; Oliguria; Impotent; Gynecomastia in men ; Attenuate; Tired; Cramp ; flushing; Tinnitus; Dizzy; Fever; Hyperkalemia ; Increased plasma creatinine; Increased blood urea; Hypernatremia; Increase liver enzymes ; Increased serum bilirubin. If you notice any unusual symptoms while using Korantrec, you should immediately notify your doctor or go to a medical facility for timely treatment.

Korantrec can interact when used with the following drugs:
Diuretics; Potassium supplements; Other antihypertensive drugs; Lithium ; Tricyclic antidepressants ; Antipsychotics; anesthetics; Addictive drug; Non-steroidal anti-inflammatory drugs; Sympathomimetic drugs; Diabetes medications; Acetylsalicylic acid; Thrombolytic drugs; beta blockers ; Alcohol. The basic information about Korantrec in the above article is for reference only. Because this is a prescription drug, patients should not use it on their own, but need to contact a specialist directly to get an appropriate prescription to ensure safety for health.