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Cefixime 50mg belongs to the group of systemic antibiotics with the main ingredient being Cefixime and in the form of powder for oral solution. Cefixime 50mg is used in the treatment of certain infections of the respiratory tract, urinary tract and genitals.
1. Uses of Cefixime 50mg
Cefixime 50mg belongs to the group of systemic antibiotics, the main ingredient is Cefixime. Cefixime is a 3rd generation cephalosporin antibiotic with bactericidal action.
Cefixime 50mg is prepared in the form of powder mixed with oral solution, packed in packages and is indicated in the following cases:
Respiratory tract infections: Pharyngitis, tonsillitis, acute and chronic bronchitis pneumonia, otitis media, typhoid, urinary tract and genital tract infections: nephritis, pyelonephritis, gonorrhea Gastrointestinal tract infections: cholecystitis, dysentery.
2. Dosage and how to use Cefixim 50mg
How to use: Cefixim 50mg drug is in the form of powder for oral solution, so to ensure safety, it is best to read carefully the instructions for use before use and only use when prescribed by a doctor.
Dosage of Cefixime 50mg specifically as follows:
Children over 12 years old (or weighing over 50kg): 400mg/time/day or can also be divided into 2 doses during the day, taking 1 time every 12 hours. This is the adult dose. Children 6 months - 12 years old: 8mg/kg body weight/day, can be taken once or divided into 2 doses during the day, 12 hours apart. Depending on the infection and the type of bacteria, the duration of treatment with Cefixime 50mg may be extended from 48 to 72 hours after the disappearance of symptoms of infection. For uncomplicated upper respiratory tract infections and urinary tract infections, the duration of treatment is 5 to 10 days. For lower respiratory tract infections and otitis media, the duration of treatment is 10 to 14 days.
Dosage of Cefixime 50mg in patients with renal failure is as follows:
Creatinine clearance over 60m/min: No dose adjustment is required. Creatinine clearance from 21 to 60ml/min: 300mg/day. Creatinine clearance less than 20ml/min: 200mg/day. Overdose of Cefixime 50mg can cause convulsions. The patient should then be symptomatic by discontinuing the drug, gastric lavage, and anticonvulsant medication (if indicated).
3. Side effects of Cefixime 50mg
Cefixime 50mg can cause some unwanted side effects with the following frequency:
Common: Abdominal pain, diarrhea, broken stools, nausea, vomiting, dry mouth, loss of appetite , flatulence. Insomnia, headache, fatigue, restlessness, dizziness. Urticaria, erythema, drug fever. Uncommon: Pseudomembranous colitis, severe diarrhea. Angioedema, anaphylaxis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis. Cefixime 50mg rarely causes transient leukopenia, thrombocytopenia, eosinophilia, decreased hematocrit and hemoglobin levels. Jaundice, hepatitis, transient elevations of liver enzymes (AST, ALT, alkaline phosphate, bilirubin and LDH). Acute renal failure, transient increases in plasma creatinine and non-protein nitrogen concentrations. Candida infection in the vagina. Rare: Convulsions, long prothrombin time. If you see any unusual symptoms when using Cefixime 50mg, you should stop taking it and contact your doctor, pharmacist or go to a medical facility for advice and guidance on appropriate management, to limit the impact on health. and life.
4. Some notes when taking Cefixime 50mg
Do not use Cefixime 50mg in people with hypersensitivity or history of hypersensitivity to the components of the drug as well as other cephalosporin antibiotics, people with a history of penicillin-induced anaphylaxis. People with cross-sensitivity between groups of beta-lactam antibiotics should be cautious when using Cefixime 50mg. People with a history of colon disease, gastrointestinal inflammation and colitis should be cautious when taking Cefixime 50mg for a long time, because it can cause severe diarrhea. Cefixime 50mg should be used with caution in pregnant women, unless clearly needed because of incomplete data and possible cross-placental cross-section of the drug. Breastfeeding women also need to be careful when using Cefixime 50mg, because it is unlikely that the drug passes into breast milk. Or the mother may have to temporarily stop breastfeeding while taking the medication. Limit activities that require high concentration such as driving, operating machinery because Cefixime 50mg can cause drowsiness, dizziness, headache. Cefixime 50mg drug may interact with drugs: increase peak concentration and AUC of the drug, decrease renal clearance and volume of distribution of the drug when co-administered with Probenecid; increased prothrombin time, with or without bleeding when used with anticoagulants; increased plasma concentrations of carbamazepine when co-administered with carbamazepine; Increased peak concentration and AUC when co-administered with nifedipine. To limit and avoid the effects of drug interactions, before taking Cefixime 50mg, patients need to tell their doctor/pharmacist about their medical history as well as any drugs they have been using, including types. : prescription and non-prescription drugs, dietary supplements, herbs. Uses Cefixim 50mg is bactericidal against a number of bacteria causing pharyngitis, tonsillitis, bronchitis, pneumonia, otitis media, nephritis, typhoid, dysentery. To ensure safety, before using, patients should discuss with their doctor to get appropriate indications.
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