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Cefprozil is a second generation cephalosporin antibiotic. The drug has dosage forms as tablets (Cefprozil 250mg, 500mg), powder for oral suspension. The 500mg tablet form is the most commonly used.1. What are the effects of Cefprozil 500mg?
Cefprozil is a semi-synthetic, second-generation cephalosporin antibiotic. The drug kills bacteria by inhibiting bacterial cell wall synthesis. It is used to treat mild to moderate respiratory tract infections and skin infections caused by susceptible strains of bacteria. Specifically:
Diseases of the upper respiratory tract: pharyngitis, tonsillitis, acute sinusitis, otitis media; Diseases of the lower respiratory tract: Acute bronchitis due to secondary bacterial infection or exacerbation of chronic bronchitis due to acute bacterial infection; Skin and skin structure diseases: Uncomplicated skin and skin structure infections; Uncomplicated urinary tract infections: Acute cystitis. Cefprozil is contraindicated in people who are allergic to its ingredients or to cephalosporin antibiotics.
Thuốc Cefprozil 500 thuộc nhóm kháng sinh cephalosporin bán tổng hợp
2. How to use and dose of Cefprozil
After knowing what Cefprozil 500mg does, the patient needs to consult about the way to use and the dose of the drug.
2.1 How to use
Drugs for oral administration. The patient should take the tablet whole with plenty of water, not with meals.
2.2 Dosage
Dosage and duration of medication depend on each specific case as prescribed by the doctor. Usual dose is:
For children from 13 years old:
Pharyngitis or tonsillitis: 500mg/time/day for 10 days; Skin and skin tissue infections, uncomplicated: Use 250mg or 500mg every 12 hours for 10 days; Respiratory tract infections: Acute sinusitis: 250mg every 12 hours for 10 days. If the patient has moderate to severe infections, the recommended dose is 500mg every 12 hours for 10 days; Secondary bacterial infection of acute bronchitis: 500mg every 12 hours for 10 days. For adults:
Acute otitis media: 500mg every 12 hours for 10 days; Pharyngitis or tonsillitis: 500mg/time/day for 10 days; Respiratory tract infections: Acute sinusitis: 250mg every 12 hours for 10 days. If the patient has moderate to severe infections, the recommended dose is 500mg every 12 hours for 10 days; Secondary bacterial infection of acute bronchitis: 500mg every 12 hours for 10 days; Acute exacerbation of chronic bronchitis: 500mg every 12 hours for 10 days; Skin and skin tissue infections, uncomplicated: 250mg or 500mg every 12 hours for 10 days. For other subjects: For patients with hepatic impairment, no dose adjustment is required. For patients with renal impairment, no dose adjustment is required if the creatinine clearance is 30 mL/min; Adjust dose to 50% if creatinine clearance < 30 mL/min. In the elderly, no dose adjustment is necessary, unless liver and kidney function are severely impaired.
3. Cefprozil side effects
In addition to learning what Cefprozil 500mg does, patients need to know the side effects of this drug in order to take appropriate prevention and treatment measures. Common side effects when treated with Cefprozil include:
Digestion: Nausea, vomiting, abdominal pain, diarrhea; Liver: Increased AST, ALT, alkaline phosphatase and bilirubin values, rarely causing jaundice and cholestasis; Hypersensitivity: Urticaria, rash (common in children), occurring a few days after starting treatment and decreasing within a few days after stopping treatment; Nervous: Dizziness, headache, insomnia, nervousness, confusion, somnolence. These disorders are all reversible; Renal: Increased BUN and serum creatinine; Hematology: Leukopenia, eosinophilia; Other side effects: Skin rash, superinfection, vaginitis, genital itching, ... When there are abnormal signs mentioned above, the patient should stop taking the drug and notify the doctor immediately. It is possible that patients need to be treated for symptoms when experiencing side effects of Cefprozil.
Thuốc Cefprozil 500mg có thể gây ra một số tác dụng phụ cho người dùng
4. Precautions when using Cefprozil
Through the above content, readers have understood what Cefprozil 500mg does. In addition to effects, patients also need to pay attention to some issues that need to be cautious before using Cefprozil:
Need to confirm a history of hypersensitivity to Cefprozil, cephalosporins, other penicillins; If an allergic reaction to Cefprozil occurs, the patient must discontinue the drug. If the brain has a severe hypersensitivity reaction, take the patient to the nearest medical center; Cefprozil can cause diarrhea caused by Clostridium difficile, ranging from mild diarrhea to colitis, which can be fatal. If this complication occurs, the patient should discontinue the drug and receive appropriate treatment (especially in pseudomembranous colitis); Cefprozil should be used with caution in patients with a personal or family history of allergies (urticaria, rash, bronchial asthma), elderly, severe renal impairment, cachexia; Safety and efficacy have not been established in pediatric patients under 6 months of age (when treating acute sinusitis, otitis media) or children under 2 years of age (when treating skin infections, pharyngitis, tonsillitis). should consult a doctor before taking the drug; When using the drug in the elderly, care should be taken when choosing a dose. Renal function may need to be monitored because the elderly are prone to renal failure; When using Cefprozil should not drive or operate machinery because the drug can cause dizziness; There are no studies showing the effects of Cefprozil on pregnant women. In nursing women, the drug may pass into breast milk. Therefore, it is best to exercise caution when using Cefprozil in pregnant and lactating women.
5. Cefprozil drug interactions
Some drug interactions and laboratory interactions with Cefprozil include:
Aminoglycoside antibiotics: Concomitant use with Cefprozil may cause nephrotoxicity; Probenecid: Concomitant use with Cefprozil increases the bioavailability of Cefprozil; Cefprozil and other cephalosporin antibiotics cause false-positive reactions in urine sugar testing with Benedict or Fehling's reagent; Cefprozil may cause a false-negative reaction to the ferricyanide test to check blood sugar. Before the risk of drug interactions that can affect the effectiveness of treatment or increase side effects, patients should inform their doctor about the medicines they are taking. If you notice any unusual symptoms while taking Cefprozil, you should immediately notify your doctor. What are the uses of Cefprozil 500mg? This medication is used to treat certain respiratory and skin infections. When taking drugs, patients should strictly follow the doctor's instructions to ensure the best treatment effect, avoiding the risk of unpredictable complications.
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