Uses of Brodicef

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Brodicef is an antibiotic with the main ingredient Cefprozil. It is indicated for the treatment of mild to moderate infections of the respiratory tract, skin and soft tissues caused by bacterial strains.

1. What is Brodicef?

Brodicef is an antibiotic that is prepared in the form of film-coated tablets containing Cefprozil 250 mg or 500 mg. Cefprozil is a 2nd generation, semi-synthetic, oral antibiotic that kills growing and dividing bacteria by inhibiting bacterial cell wall synthesis.
2. Indications of Brodicef Brodicef is indicated in the treatment of mild to moderate infections caused by susceptible strains of bacteria such as:
Upper respiratory tract: Pharyngitis, tonsillitis caused by St. Pyogenes. Otitis media caused by St. Pneumoniae, H. Influenzae (including β-Lactamase-producing strains) and Moraxella Catarrhalis. Acute sinusitis caused by: St. Pneumoniae, H. Influenzae (β-Lactamase strain) and Moraxella Catarrhalis (including β-Lactamase strain). Lower respiratory tract: Secondary infection in acute bronchitis or exacerbation of chronic bronchitis caused by St Pneumoniae, H. Influenza (including β-Lactamase strains) and Moraxella Catarrhalis (including β- Lactamase). Skin and structures: Uncomplicated skin and structural infections caused by St. Aureus (including Penicillinase-producing strains) and St. Pyogenes. Surgery is required in cases of abscesses.

3. Contraindications of the drug Brodicef

Brodicef is contraindicated in the following cases:
Hypersensitivity to the components of the drug; Allergy to Cephalosporin antibiotics. 4. Side effects of Brodicef The side effects of Cefprozil are similar to those of oral Cephalosporin antibiotics. Cefprozil was generally tolerated in controlled clinical studies. Approximately 2% of patients discontinued treatment with cefprozil due to adverse events.
Common side effects when taking Cefprozil include:
Gastrointestinal tract: Diarrhea, nausea, vomiting and abdominal pain. Hepatobiliary: Increased AST, ALT, alkaline Phosphatase and Bilirubin. A few cases of jaundice. Hypersensitivity: Rash, urticaria. These reactions are more common in children. Symptoms appeared after a few days of taking the drug and subsided immediately after stopping. Nervous: Dizziness, hyperactivity, headache, insomnia and confusion. All heal on their own. Inform your doctor about any unwanted effects you may experience while using the drug.
Treatment instructions: Stop using the drug. With mild adverse reactions, usually only discontinuation of the drug is necessary. In case of severe hypersensitivity or allergic reaction, it is necessary to conduct supportive treatment (keep breathing and use Epinephrine, breathe oxygen, use antihistamines, corticosteroids...).

5. How to use Brodicef

Dosage is adjusted according to individual patient needs. This medicine is for use only as prescribed by your doctor.
How to use tablets : Take orally with a glass of water.
Dosage: For adults and children from 13 years old and above:
Pharyngitis, tonsillitis: Dose 500 mg/day 1 time, 10 days treatment. Acute sinusitis (moderate to severe severity may require higher doses): 500 mg twice daily for 10 days. Secondary infection in case of acute bronchitis or exacerbation of chronic bronchitis: Dose 500 mg, twice daily, 10 days treatment. Uncomplicated structural dermatitis: 250 mg/day 2 times or 500 mg x 1-2 times/day, treatment for 10 days. Patients with renal impairment: Brodicef can be prescribed for patients with renal impairment with the following dosage regimen: Creatinine clearance 30 ml/120 minutes dose and duration of treatment as normal people. Creatinine clearance 0 ml/29 min: 50% of standard dose, as normal. Give the patient Brodicef to drink after hemodialysis. Patients with hepatic impairment: No dose adjustment is required.

6. Be careful when using Brodicef

When using Brodicef, caution should be exercised in the following cases:
Before starting treatment with Brodicef, previous allergic reactions should be checked. If an allergic reaction to Cefprozil occurs, the drug should be discontinued. Acute or severe hypersensitivity reactions, if encountered, require emergency measures. Antibiotic treatment can cause mild to life-threatening pseudomembranous colitis. Patients should be treated appropriately if pseudomembranous colitis is diagnosed. In mild cases, just stopping the drug, the disease can go away. In patients with known or suspected renal insufficiency, clinical monitoring and appropriate laboratory tests should be performed before and after treatment. Reduce the total daily dose of Cefprozil in these cases. Caution should be exercised when cephalosporins, including cefprozil, are prescribed to patients receiving diuretics because of their effect on renal function. Caution should be exercised when prescribing Cefprozil to patients with a history of intestinal disease, especially colitis. Positive reactions to the direct Coombs test have been reported with cephalosporin antibiotics. Driving and operating machines: Patients may experience dizziness while taking the drug. Therefore, patients should be warned about this side effect if they drive or operate machinery during treatment with Brodicef. Pregnancy: Fetal toxicity tests in rats and rabbits with oral administration of Ccefprozil at doses equal to 0.8:8.5 and 18.5 times the maximum human dose revealed no harm to the fetus. . However, because there is no evidence in humans, the use of the drug in pregnant women should be done when absolutely necessary. Lactation: Small amounts (less than 0.3% of the dose) have been found in breast milk in a single dose of 1 gram. Mean 24-hour drug concentrations ranged from 0.25 to 3.3 g/mL. Therefore, caution should be exercised when administering the drug because the effect on the neonate is not fully known. In summary, the drug Brodicef has the effect of inhibiting the growth and development of bacteria, thereby treating diseases caused by infections. To ensure effective treatment and avoid side effects, patients need to take prescription drugs or consult a doctor or pharmacist.

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