Several diagnostic scores have been developed for the diagnosis and prognosis of AFB-negative tuberculosis. Each score has its own advantages and disadvantages as well as different sensitivities and specificities.

Diagnosis of negative AFB tuberculosis will be based on history of exposure, clinical and X-ray suspicion. Thus, the diagnosis of tuberculosis or not will depend largely on the experience of the clinician. Tuberculosis in children is a serious and complicated disease with long-term and complicated treatment, so tuberculosis vaccination is the safest and most effective method of disease prevention.