Pathological diagnosis of multiple myeloma on biopsy tissue is very difficult and complicated because the lesions are very diverse. It is necessary to combine histopathological images and sufficient immunohistochemical markers to diagnose the morphology of the lesions, the ratio and morphology of plasma cells, the ratio of plasma cells in the bone marrow as well as determine malignant plasma cells or activated plasma cells.

If you have been diagnosed with multiple myeloma, your cancer care team will discuss your treatment options with you. It is important that you think carefully about each of your options. Consider the benefits of each treatment option to limit the possible side effects and risks.

Multiple myeloma usually affects areas where the bone marrow is still active in adults, such as the skull, spine, ribs, pelvis, and shoulder blades. Other areas, such as the bones of the hands, feet, forearms, and legs, are less commonly affected.