Obeticholic Acid is used in the treatment of certain liver diseases such as diabetic cholangitis-PBC. Obeticholic Acid works by causing the liver to make less bile and helping bile leave the liver, slowing the progression of the disease.

Uforgan's main ingredient is Ursodeoxycholic Acid, which is effective in treating gallstones by reducing cholesterol levels in bile. Uforgan is indicated for the treatment of gallstones, primary cirrhosis, primary biliary cholangitis, cholestatic liver disease or prevention of gallstone formation.

Primary cholangitis is a serious autoimmune disease that usually occurs in people aged 40 years and older. This disease can damage the liver, leading to primary cirrhosis. If not treated early, the disease will cause dangerous complications such as osteoporosis, cholangiocarcinoma, and even death.

Autoantibodies play an important role in the diagnosis and classification of autoimmune liver disease. Panel test qualitatively 14 autoantibodies in autoimmune liver disease including: AMA-M2, M2-3E, Sp100, PML, gp210, LKM-1, LC-1, SLA/LP, SS-A, Ro-52 , Scl-70,CENP A, CENP B, PGDH are currently being performed at DKQT Vinmec Times City hospital with high accuracy.

The interaction between bile acids and the gut microbiota is implicated in the pathophysiology of many intestinal and gastrointestinal diseases, especially cholestatic liver disease. In particular, the progression of autoimmune cholestatic liver diseases also affects the composition of the gut microbiota, exacerbating the development of cholestasis in this interactive cycle.