Latent autoimmune diabetes in adults (LADA) is a special form of diabetes also known as type 1.5 diabetes because of its late onset in adults with similar symptoms to type 2 diabetes but with autoimmune antibodies like type 1 diabetes. Autoimmune antibody tests are indispensable to diagnose type 1.5 diabetes.

Latent autoimmune diabetes in adults or LADA diabetes is a very special and rare form of diabetes that is not included in the usual diabetes classification groups such as type 1 diabetes, type 2 diabetes, gestational diabetes. Currently, very few people are diagnosed with this type of diabetes because the rate is low and diagnosis requires many immunological tests. The pathogenesis of this type of diabetes is due to the interweaving of clinical and biochemical manifestations as well as treatment methods, making LADA diabetes the metabolic disease that is currently receiving the most attention.

Autoantibodies are proteins produced by the body's immune system and are considered evidence of type 1 diabetes. Therefore, autoantibody tests are very valuable in diagnosing type of diabetes, one of which is the ICA test.

Type 1 diabetes is a form of diabetes with a distinct mechanism caused by an immune response, in which the presence of antibodies is evidence of type 1 diabetes. Therefore, the Anti-GAD test is one of the necessary paraclinical tests to diagnose diabetes.