Diagnosis of lower limb arterial disease can be based on 2D ultrasound and color Doppler ultrasound to determine the location and morphology of the lesion and assess the hemodynamics of the flow at and after the lesion.

Digital subtraction angiography (DSA) with catheter aspiration of thrombus is performed by inserting a catheter of appropriate diameter to the location of the thrombus, then applying negative pressure suction to remove the thrombus.