The ceruloplasmin test measures the amount of ceruloplasmin, a copper-binding substance, in the body. It is often ordered for people with symptoms of copper deficiency, Wilson's disease, Menkes syndrome, and for early screening of Wilson's disease in people who do not have symptoms.

Copper is an essential substance in the human body, ceruloplasmin is a protein that contains copper, participating in the body's copper metabolism. In the liver, copper binds to ceruloplasmin to form ceruloplasmin and then releases it into the blood. To diagnose Wilson's disease or evaluate copper metabolism, the doctor will order a ceruloplasmin test.

In the liver, copper binds to ceruloplasmin to form ceruloplasmin, which is then released into the blood. Up to 95% of copper in the blood is bound to ceruloplasmin. Therefore, to diagnose Wilson's disease or evaluate copper metabolism, your doctor will order a ceruloplasmin test.