This is an automatically translated article.
Article written by Doctor Bui Thi Phuong Hoa - Vinmec High-Tech Center
NIPT (non-invasive prenatal test) – A non-invasive prenatal screening test is a test done from the 10th week of pregnancy to help assess the risk of the fetus with certain genetic syndromes with unique features. High accuracy and absolute safety for mother and fetus.
1. What syndromes does NIPT test for?
During pregnancy, from the 5-6th week of pregnancy, some amount of DNA (genetic material) of the fetus is released and moves freely in the maternal blood stream. Therefore, scientists based on this trait, through maternal peripheral blood draw, separate these free DNA and conduct genetic analysis to assess fetal risk with the aim of limiting tests. invasive testing harms mother and baby.
Trisomy 21 (Down syndrome), trisomy 18 (Edward syndrome), trisomy 13 (Patau syndrome), sex chromosome number abnormalities (eg Turner syndrome) (45,X), Klinefelter (47,XXY), 47,XXX, 47,XYY) and some microdeletion syndromes.
Tam nhiễm sắc thể 21
2. In which case should you choose NIPT?
You have prenatal screening tests : ultrasound, combined test gives high risk results You do not have the results of the first 3 months screening test due to time delay or where you live do not have this test You want know you are at high risk before having an invasive diagnostic test such as amniocentesis or chorionic villus sampling, which still carries a low risk of miscarriage You are at high risk (eg, an elderly woman or a baby previously diagnosed with Down or other chromosomal disorders)
Sinh thiết gai nhau qua cổ tử cung
3. What will you get when you screen for NIPT at Vinmec hospital?
Customers will be fully consulted and consulted about the principles, meanings, and possible results when performing NIPT with a genetic pathologist. Customers will not receive the results without consulting. genetic counseling Process of taking and transporting blood samples containing mother and child DNA according to ISO 15189/2012 standard and sending to BGI Gene Research Institute located in Hong Kong for analysis Ensure privacy and confidentiality of customer information Clean room system, modern equipment Supported by insurance when results are positive or false negative + For positive results: experts will explain in more detail, transfer to obstetrician for treatment for the next assignment. If it is necessary to carry out invasive testing measures (amniocentesis, chorionic villus sampling, ...) to re-evaluate the risk of disease, pregnant women will be supported with costs when performing at hospitals/facility health facility is certified and can issue a VAT invoice.
Chọc ối làm xét nghiệm
+ For false negative results: only <0.1% happens in case the test result is low risk but the child is still born with the disease (list of diseases according to the insurance policy), then the family will receive compensation according to the commitment of BGI
Customers can directly go to Vinmec Health system nationwide to visit or book an appointment on the website for service.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
