What is Zentel?

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1. Uses of the drug Zentel

What is Zentel drug? Zentel medicine has the main ingredient Albendazole 200mg (also known as Zentel 200mg drug). Albendazole has anthelmintic and protozoan activity, against intestinal and tissue parasites. Albendazole's activity against worms, eggs and larvae comes from its ability to inhibit tubulin polymerization, which disrupts the worm's metabolism, causing the worm to be depleted of energy, immobilized and destroyed.
Zentel drug has a broad spectrum of activity on intestinal worms: Pinworms, roundworms, hookworms, strongyloides, helminths, whipworms, muscle and skin larvae, tapeworms and tapeworm larvae in tissue.
Indications for the use of Zentel:
Treatment of infections with roundworms, hookworms, roundworms, pinworms; Treatment of strongyloidiasis and tapeworm infections if sensitive to the ingredient Albendazole; Treatment of parenchymal neurotrophic larval diseases (due to lesions caused by larvae of pork tapeworms, beef tapeworms); Treatment of cysts in the liver and peritoneal cavity caused by larvae of the dog tapeworm Echinococcus granulosus. Contraindications to using Zentel:
Patients with a history of allergy to the drug's ingredients/excipients; People who are suffering from an acute illness, having a fever over 38.5°C; People who are suffering from a number of chronic diseases including: liver failure, heart failure, kidney failure, bronchial asthma; Pregnant person.

2. How to use and dose Zentel

How to use: When should Zentel be taken? Users should take the drug with food at the main meal of the day. Some people, especially children, may have difficulty swallowing the tablet whole. At this point, the patient can chew the medicine with a little water or crush the tablet. If the patient does not recover after 3 weeks, a second course of treatment can be used. There is no need to fast or enema when taking Zentel.
Dosage:
Adults and children over 2 years old: Use Zentel 400mg or 2 Zentel 200mg tablets; Children from 1 - 2 years old: Use Zentel 200mg dose; Elderly: There is limited experience in using Zentel in people over 65 years of age. Reports do not require dose adjustment but should be used with caution in the elderly with hepatic dysfunction; Patients with renal impairment: No dose adjustment of Zentel is required but close monitoring is required in patients with impaired renal function; Patients with hepatic impairment: Patients with abnormal liver function test results should be closely monitored before using Zentel. In order to have a complete cure in case of pinworm infection, it is necessary to take measures to keep strict hygiene, and to treat relatives with Zentel medicine, who live in the same house.
Overdose: When Zentel overdose, the patient should be taken to the hospital immediately for timely treatment.

3. Side effects of the drug Zentel

Some side effects patients may experience when using Zentel:
Upper gastrointestinal symptoms: Epigastric pain, abdominal pain, nausea, vomiting, diarrhea; Neurological symptoms: Headache, dizziness; Hepatobiliary symptoms: Increased liver enzymes; Skin and subcutaneous tissue symptoms: Erythema multiforme, Stevens-Johnson syndrome; Immune system symptoms: Rash, itching, hives. In general, the side effects of Zentel are very rare. When experiencing side effects due to drugs, patients should consult their doctor for appropriate advice.

4. Be careful when using Zentel

Some notes users need to remember before and while using Zentel:
Be careful when using Zentel in the elderly, children, people with liver and kidney disease,...; Zentel may not be able to treat pre-existing CNS larval cysts (especially in areas of high fluke infection). The patient may have some neurological symptoms (convulsions, increased intracranial pressure, focal signs caused by an inflammatory response if the brain parasites die). The above symptoms may appear soon after treatment with Zentel, when appropriate steroid and anticonvulsant therapy should be initiated immediately; In order to avoid using Zentel in early pregnancy without knowing it, women of reproductive age should take the drug during the first week of their menstrual cycle or after a negative pregnancy test; Zentel should not be used while breastfeeding, unless authorized by your doctor.

5. Zentel drug interactions

Some drug interactions of Zentel include:
Co-administration of Zentel with the following drugs may affect the effectiveness of the drug: Ritonavir, carbamazepine, phenobarbital, phenytoin, theophyllin; The antiparasitic drug Praziquantel, when co-administered with Zentel, increases plasma concentrations of the active metabolite of Albendazole (the main ingredient of Zentel). When using Zentel, patients should strictly follow the doctor's instructions. At the same time, patients need to inform the doctor about their health history, drugs / supplements they are using to receive appropriate advice, avoid the risk of drug interactions or the occurrence of difficult side effects. measure.
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