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Ursobil 300 mg drug has the main ingredient ursodeoxycholic acid. This drug is used to treat primary biliary cirrhosis and dissolve gallstones. Ursobil 300mg is prepared in the form of tablets, packing: box of 3 blisters x 10 tablets.
1. What is Ursobil 300mg? Uses
Ursodeoxycholic Acid in Ursobil 300mg is a form of Chenodeoxycholic Acid (acid available in the body's bile). Ursobil 300 mg drug has the following effects:Helps increase the concentration of this substance according to the dose to become the main bile acid. Replace and displace toxic endogenous bile acids that tend to accumulate in liver and biliary diseases. Helps protect the epithelial cells of the bile ducts from damage and against the bad effects of bile acids. Helps prevent self-destruction of liver cells and alter or maintain immune function. It also stimulates bile secretion from liver cells and bile ducts. Helps enhance the solubility of cholesterol in bile to convert gallstones into gallstones by: Reducing cholesterol excretion into bile: Limiting cholesterol absorption in the intestine and synthesis in the liver. Increase total bile acids.
2. Indications and contraindications for taking Ursobil 300mg
2.1 Indications to use Ursobil 300mg drug Ursobil 300mg is indicated in the following cases:
Restore liver function for patients with primary biliary cirrhosis. Dissolve gallstones in the following cases: The stones are not calcified, have a diameter of less than 20mm, do not block X-rays; Stones are present when the gallbladder is still functioning well or crumbling or recurrent stones in the bile ducts after surgery or for people who cannot have their gallbladder removed or who tend to have an increased risk during surgery. 2.2 Contraindications to the drug Ursobil 300mg Ursobil 300mg is contraindicated in the following cases:
People with hypersensitivity to the components of the drug; People with complete bile duct obstruction; People with rapidly progressing hepatitis; People who often have pain in the upper abdomen; People with acute biliary tract disease or cholecystitis; People with calcified stones can be seen on X-ray; Children under 12 years old; Pregnant. 3. Dosage and how to use Ursobil 300mg How to use: Ursobil 300mg is used orally. Patients should take Ursobil 300mg after meals.
Dosage:
In the case of patients with primary biliary cirrhosis: Dosage is from 13-15 mg/kg/day, divided into 2-4 times. Note: Within 6 months from taking Ursobil 300mg, it is recommended to have liver function and Bilirubin tested once a month. After that, you should go for a checkup every 6 months. In case of dissolution of gallstones: Dosage is from 8-12 mg/kg/day, divided into 2-3 times. After taking the drug, but the stone has completely dissolved, it is still necessary to continue using the drug for another 3-4 months (the duration of use should not exceed 2 years). In case the gallstones do not decrease after 12 months of taking the drug, the drug must be changed. An overdose of Ursobil 300mg can lead to diarrhea. At this time, the patient needs to stop the drug immediately and go to the nearest medical facility for timely treatment.
In case you miss a dose of Ursobil 300mg, you should take it as soon as possible. However, if it is almost time for the next dose, skip the missed dose and take a new dose.
4. Undesirable effects when using Ursobil 300mg
The process of using Ursobil 300mg may encounter side effects such as:
Diarrhea, pasty stools (common). Change in toilet habits (rare). Severe right upper abdominal pain (very rare). Get angry. Calcified gallstones. Liver problems are severe, but should subside once the medication is stopped. If you experience the above symptoms, you need to stop using Ursobil 300mg and go to the nearest medical facility for timely examination and treatment.
5. Drug Interactions Ursobil 300mg Care should be taken when combining Ursobil 300 with:
Colestipol, Cholestyramine or antacids containing groups of Hydroxide and Aluminum Oxide: In case of combined use with these types, it is necessary to Drink at least 2 hours apart. Cyclosporin because it can increase the absorption of this substance in the intestine. In case of being treated with Cyclosporin, it is necessary to pay attention to adjust the dose appropriately. Ciprofloxacin because it can reduce its absorption in the body. Nitrendipine because it can reduce peak concentrations and AUCs of this substance. Drugs that increase cholesterol secretion in bile (Estrogen, hormonal contraceptives, some lipid-lowering drugs) because they can increase gallstones, have an antagonistic effect on drugs. You need to inform your doctor / pharmacist about the drugs / supplements you are using to avoid interactions.
Above is all information about Ursobil 300mg, you need to read carefully the instructions for use, consult your doctor / pharmacist before use. Absolutely do not arbitrarily buy drugs to treat at home because there may be unwanted side effects.
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